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Edited By
Andres Kriete, Drexel University, Philadelphia, PA and Coriell Institute for Medical Research, Camden, NJ, USA
Roland Eils, Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, and Bioinformatics and Functional Genomics, Institute of
Pharmacy and Molecular Biotechnology, University of Heidelberg, Germany
Audience
Graduate students and researchers in Bioinformatics, Biocomputing, Theoretical Biology, Biochemistry/Biophysics, and Cell Biology.
Contents
CONTENT
1. Introducing Computational Systems Biology. A Kriete and R Eils
I. Enabling Information and Integration Technologies for Systems
Biology:
2. Databases for Systems Biology. J Eils, C Lawerenz, K Astrahantseff, M Ginkel, and R Eils
Natural Language Processing and
Ontology-enhanced Biomedical Literature Mining for Systems Biology. X Hu
Integrated Imaging Informatics. B Parvin, G Fontenay, Q Yang,
and MH Barcellos-Hoff
Simpathica: A Computational Systems Biology Tool within the Valis Bioinformatics Environment.
B Mishra, M Antoniotti,
S Paxia and N Ugel
Standards, Platforms and Applications. HM Sauro
II. Foundations of Biochemical Network Analysis and Modeling
7. Introduction
to Computational Models of Biochemical Reaction Networks.
FJ Bruggeman, BM Bakker, JJ Hornberg, and HV Westerhoff
8. Biological Foundations
of Signal Transduction and the Systems Biology Perspective. U Klingm ller
9. Reconstruction of Metabolic Network from Genome Information
and Its Structural and Functional Analysis.
H-W Ma and A-P Zeng
10. Integrated Regulatory and Metabolic Models. M.W. Covert
III. Computer
Simulations of Dynamic Networks
11. A Discrete Approach to Network Modeling. R Laubenbacher and P Mendes
12. Gene Networks: Estimation,
Modeling and Simulation. S Imoto, H Matsuno, and S Miyano
13. Computational models for circadian rhythms: Deterministic versus stochastic
approaches.
J-C Leloup, D Gonze, and A Goldbeter
IV. Multi-Scale Representations of Cells and Emerging Phenotypes
14. Multistability
and Multicellularity: Cell Fates as High-dimensional Attractors of Gene Regulatory Networks. S Huang
15. Spatio-Temporal Systems Biology.
A Ghosh, D Miller, R Zou, B Sokhansanj,and A Kriete
16. Cytomics?from cell states to predictive medicine. G Valet, RF Murphy, JP Robinson,
A T rnok, A Kriete
17. The IUPS Physiome Project: Progress and Plans. P Hunter, K Burrowes, J Fernandez, P Nielsen,
N Smith, and M Tawhai
Subject Index
| Bibliographic details |
Hardbound, 424 pages, publication date: OCT-2005
ISBN-13: 978-0-12-088786-6
ISBN-10: 0-12-088786-X
Imprint: ACADEMIC PRESS
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Last update: 30 Nov 2009
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