 |
|
| THE MANY FACES OF RNA
| |
| | |
|
|
To order this title, and for more information, click here
Edited By
D. Eggleston, Smithkline Beecham Parmaceuticals, Harlow, Essex, U.K.
Catherine Prescott, SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania, U.S.A.
Neil Pearson, SmithKline Beecham Pharmaceuticals, Harlow, Esses, U.K.
Description
The Many Faces of RNA is the subject for the eighth SmithKline Beecham Pharmaceuticals Research Symposia. It highlights
a rapidly developing area of scientific investigation. The style and format are deliberately designed to promote in-depth presentations
and discussions and to facilitate the forging of collaborations between academic and industrial partners.
This symposium focuses on several
of the many fundamental, advancing strategies for exploring RNA and its functions. It emphasizes the interplay between biology, chemistry,
genomics, and molecular biology which is leading to exciting new insights and avenues of investigation. The book explores RNA as a therapeutic
target, RNA as a tool, RNA and its interactions, along with chemical, computational, and structural investigations.
Contents
Introduction.
Overview:
RNA as a Therapeutic Target for Bleomycin, S.M. Hecht.
RNA: Chemistry, Structure
and Interactions:
Synthetic RNA Modification and Cross-linking Approaches towards the Structure of the Hairpin Ribozyme and
the HIV-1 Tat Protein Interaction with TAR RNA, M.J. Gait, D.J. Earnshaw, M.A. Farrow, and N.A. Naryshkin.
The Ribosome - The
Universal Protein-synthesizing Machine, R. Brimacombe.
tRNA Recognition by Aminoacyl-tRNA Synthetases, S. Cusack, A. Yaremchuk,
and M. Tukalo. RNA-Protein Recognition During RNA Processing and Maturation, G. Varani.
RNA as a Target/RNA as
a Tool:
Exploiting RNA: Potential Targets, Screens and Drug Development, C.D. Prescott, L. Hegg, K. Nurse, R. Gontarek,
H. Li, V. Emerick, T. Sterner, M. Gress, G. Thom, S. Guth, and D. Rispoli.
Structural Basis for Aminoglycoside Antibiotic Action, J.D. Puglisi.
Protein-RNA Recognition in a Highly Conserved Ribosomal Domain Targeted by Thiazole Antibiotics, D.E. Draper.
Rnase P and Its Substrate, L.A. Kirsebom.
Interfering with Gene Function at the RNA Level with Oligoymes - the Development of
New Tools and Therapeutics, B.S. Sproat, S.T. George, M. Ma, and A.R. Goldberg.
Progress towards Therapeutic Application of
SELEX-derived Aptamers, B. Polisky.
Catalysis of Organic Reactions by RNA - Strategies for the Selection of Catalytic RNAs, A. Jaschke.
Conclusions and Opportunities, B.W. Metcalf.
Appendix: Abstracts of Posters.
Index.
| Bibliographic details |
Hardbound, 228 pages, publication date: DEC-1997
ISBN-13: 978-0-12-233210-4
ISBN-10: 0-12-233210-5
Imprint: ACADEMIC PRESS
|
| Price and Ordering |
Price:
GBP 115
USD 185
EUR 135.95
|  |
Books and book related electronic products are priced in US dollars (USD), euro (EUR), and Great Britain Pounds (GBP). USD prices apply to the Americas and Asia Pacific. EUR prices apply in Europe and the Middle East. GBP prices apply to the UK and all other countries.
|
See also information about conditions of sale & ordering procedures, and links to our regional sales offices.
|
092/900
Last update: 7 Sep 2009
|
|
| |
| | |
|
|
| |
Home | Elsevier Sites | Privacy Policy | Terms and Conditions | Feedback | Site Map | A Reed Elsevier Company