 |
|
| ACETYLCHOLINE IN THE CEREBRAL CORTEX, 145
| |
| | |
|
|
To order this title, and for more information, click here
Edited By
L. Descarries, Departments of Pathology and Cellular Biology and of Physiology, Centre de Recherche en Science Neurologiques, Université de Montréal, QC, Canada
K. Krnjevic, Anaesthesia Research Unit and Department of Physiology, McGill University, Montreal, QC, Canada
M. Steriade, Laboratory of Neurophysiology, Department of Anatomy and Physiology, Faculty of Medicine, Université Laval, Quebec, QC, Canada
Included in series
Progress in Brain Research, 145
Description
Comprehensive exposé, by leading neuroscientists, of current knowledge on the neurotransmitter acetylcholine in the cerebral cortex.
All aspects of the subject are covered, from its most elementary, at the molecular and cellular levels, to its systemic and holistic
implications, including its role in cognition and involvement in human diseases and therapeutics.
The twenty-two chapters are grouped
under four main headings : I. Functional Morphology of the Acetylcholine Innervation in Cerebral Cortex (Including Hippocampus); II.
Modes of Action of Acetylcholine in the Cerebral Cortex; III. Cortical Properties and Functions Modulated by Acetylcholine, and IV. Clinical,
Pathological and Therapeutic Implications. This broad perspective updates the reader on recent advances and future trends in the study
of a major neuromodulatory system in brain.
Contents
List of contributors. Preface. Acknowledgements.
I. The Acetylcholine Innervation of Cerebral Cortex.
1. Phylogenetic
and ontogenetic aspects of the basal forebrain cholinergic neurons and their innervation of the cerebral cortex
(K. Semba). 2. Structural
determinants of the roles of acetylcholine in cerebral cortex (L. Descarries, N. Mechawar et al.). 3. Muscarinic acetylcholine
receptor subtypes in cerebral cortex and hippocampus (L.A. Volpicelli, A.I. Levey). 4. The cholinergic innervation of the human cerebral
cortex
(M.-M. Mesulam).
II. Modes of Action of Acetylcholine in the Cerebral Cortex.
5. Synaptic mechanisms modulated
by acetylcholine in cerebral cortex (K. Krnjević). 6. Functional and molecular characterization of neuronal nicotinic ACh receptors
in rat hippocampal interneurons (J.L. Yakel, Z. Shao). 7. The nicotinic acetylcholine receptor subtypes and their function in the hippocampus
and cerebral cortex
(M. Alkondon, E.X. Albuquerque). 8. Studies of muscarinic neurotransmission with antimuscarinic toxins (L.T. Potter,
D.D. Flynn et al.).
III. Cortical Properties and Functions Modulated by Acetylcholine.
9. Hyperactivation of
developing cortical circuits by acetylcholine and the ontogeny of abnormal cognition and emotion: findings and hypothesis (A. Peinado,
D.P. Calderon). 10. Synaptic mechanisms and cholinergic regulation in auditory cortex (R. Metherate, C. Hsieh). 11. Activity, modulation
and role of basal forebrain cholinergic neurons innervating the cerebral cortex (B.E. Jones). 12. Cholinergic modulation of the cortical
microvascular bed
(E. Hamel). 13. Acetylcholine systems and rhythmic activities during the waking-sleep cycle (M. Steriade). 14. Cholinergic
mechanisms mediating anaesthetic induced altered states of consciousness (S.B. Backman, P. Fiset, G. Plourde). 15. High acetylcholine
sets circuit dynamics for attention and encoding; Low acetylcholine sets dynamics for consolidation
(M.E. Hasselmo, J. McGaughy).
IV.
Clinical, Pathological and Therapeutic Implications.
16. Knock-out and knock-in mice to investigate the role of nicotinic receptors
in the central nervous system (N. Champtiaux, J.-P. Changeux). 17. Nicotinic modulation of thalamocortical neurotransmission (P.B.S.
Clarke). 18. Amyloid β peptides and central cholinergic neurons: functional interrelationship and relevance to Alzheimer's disease
pathology (S. Kar, R. Quirion). 19. Nicotinic receptor mutations in human epilepsy (O.K. Steinlein). 20. Neurochemistry of consciousness:
cholinergic pathologies in the human brain
(E.K. Perry, R.H. Perry). 21. Functional studies of cholinergic activity in normal and Alzheimer
disease states by imaging technique (A. Nordberg). 22. Paying attention to acetylcholine: the key to wisdom and quality of life? (P.J.
Whitehouse). Subject Index.
| Bibliographic details |
Hardbound, 344 pages, publication date: OCT-2003
ISBN-13: 978-0-444-51125-6
ISBN-10: 0-444-51125-3
Imprint: ELSEVIER
|
| Price and Ordering |
Price:
USD 250
GBP 125
EUR 185
|  |
Books and book related electronic products are priced in US dollars (USD), euro (EUR), and Great Britain Pounds (GBP). USD prices apply to the Americas and Asia Pacific. EUR prices apply in Europe and the Middle East. GBP prices apply to the UK and all other countries.
|
See also information about conditions of sale & ordering procedures, and links to our regional sales offices.
|
095/945
Last update: 4 Sep 2009
|
|
| |
| | |
|
|
| |
Home | Elsevier Sites | Privacy Policy | Terms and Conditions | Feedback | Site Map | A Reed Elsevier Company