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| ANTIVIRAL NUCLEOSIDES
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Chiral Synthesis and Chemotherapy
To order this title, and for more information, click here
Edited By
C.K. Chu, College of Pharmacy, University of Georgia, Athens, GA, USA
Description
• Up-to-date review on the chemistry and biology of nucleosides
• Modern synthetic methodology
• Comprehensive
coverage of antiviral nucleosides
This book summarizes the recent advances in nucleosides chemistry and chemotherapy over the past
10-15 years. It covers recently discovered nucleoside antiviral agents, their therapeutic aspects and biochemistry, and also extensive
reviews on their chiral synthesis.
Contents
1. Recent Advances in Antiviral Nucleosides.
(G. Gumina, Y. Choi, C.K. Chu). Introduction. Structural features of nucleosides
as antiviral agents. 2'-Deoxy nucleosides and related analogs. 2',3'-Dideoxy nucleosides and related analogues. 2',3'-Unsaturated nucleosides
and related analogues. Nucleosides with a heterocyclic sugar ring moiety. 3- or 4-Membered ring nucleosides. Acyclonucleosides. Ribofuranosyl
nucleosides. References.
2. Chiral synthesis of antiviral nucleosides from carbohydrate templates.
(G. Gumina, S. Olgen,
C.K. Chu). Introduction. 4'-Thiofuranose nucleosides. Iso- and apio nucleosides. Oxathiolane and dioxolane nucleosides. Cyclopentyl carbocyclic
nucleosides. Cyclopropyl carbocyclic nucleosides. C-Nucleosides. Fluorinated nucleosides. Acyclonucleosides. Miscellaneous nucleosides.
References.
3. Oxathiolane and dioxolane nucleosides: Synthesis and antiviral activity.
(G. Gumina, J.S. Cooperwood,
C.K. Chu). Introduction. Oxathiolane nucleosides. Synthesis. Antiviral activity. Combination therapy. Dioxolane nucleosides. Synthesis.
Antiviral activity. References.
| Bibliographic details |
Hardbound, 268 pages, publication date: OCT-2003
ISBN-13: 978-0-444-51319-9
ISBN-10: 0-444-51319-1
Imprint: ELSEVIER
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| Price and Ordering |
Price:
USD 200
GBP 121
EUR 142.95
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092/943
Last update: 4 Sep 2009
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