By
John Cavanagh, North Carolina State University,
Raleigh, NC 27695
Wayne J. Fairbrother, Genentech, Inc.,
San Francisco, CA 94080-4990
Arthur G. Palmer, III, Columbia University,
New York, NY 10032-3702
Nicholas J. Skelton, Genentech, Inc.,
San Francisco, CA 94080-4990
Mark Rance, University of Cincinnati,
Cincinnati, OH 45267-0524
Description
Protein NMR Spectroscopy combines a comprehensive theoretical treatment of NMR spectroscopy with an extensive exposition
of the experimental techniques applicable to proteins and other biological macromolecules in solution. Beginning with simple theoretical
models and experimental techniques,
Protein NMR Spectroscopy develops the complete repertoire of theoretical principles
and experimental techniques necessary for understanding and implementing the most sophisticated NMR experiments.
Important new techniques
and applications of NMR spectroscopy have emerged since the first edition of this extremely successful book was published in 1996. The
second edition includes new sections describing measurement and use of residual dipolar coupling constants for structure determination,
TROSY and deuterium labeling for application to large macromolecules, and experimental techniques for characterizing conformational dynamics.
In addition, the treatments of instrumentation and signal acquisition, field gradients, multidimensional spectroscopy, and structure
calculation are updated and enhanced.
Protein NMR Spectroscopy is written as a graduate-level textbook and will
be of interest to biochemists, chemists, biophysicists, and structural biologists who utilize NMR spectroscopy or who wish to understand
the latest developments in this field.
Audience:
Graduate students, postdoctoral fellows, established researchers interested in structural biology
