Biochemistry

Win an iPad with Elsevier Mobile Application Competition
Submit your app idea by 31 May 2012
External link  http://elsevierauthormobileapp.com


 

Pavel Pevzner holds the Ronald R. Taylor Chair in Computer Science at UCSD. He received his PhD in 1988 from Moscow Institute of Physics and Technology. Pevzner is the author of the textbooks "Computational Molecular Biology: An Algorithmic Approach" (2000) and "Introduction to Bioinformatics Algorithms" (2004). He is an executive editor of the "Journal of Computational Biology," and co-founder of the International Conference on Research in Computational Biology (RECOMB). In 2006 he was named HHMI Professor. In 2010 he was elected to the Board of Directors of the Human Proteome Organization. He directs the Interdisciplinary Graduate Program in Bioinformatics and Systems Biology and the Center for Algorithmic and Systems Biology at UCSD. Since 2008 he directs the NIH Center for Computational Mass Spectrometry at UCSD. In 2010 he was elected Fellow of the Association for Computing Machinery (ACM).

Evaluating Advanced LC/MS/MS tools and applications for targeted and untargeted molecular lipidomics: From molecular lipidomics to biomarker assays

Date: Thursday 26 April 2012
Time: 09:30 BST / 10:30 CEST / 14:00 IST (India). Check your local time zone External linkhere
Where: External linkRegistration is FREE. Simply, follow this link to reserve your place now

Who should attend:
Job roles:
Healthcare Scientists, Life Science Researchers, Laboratory Medicine Researchers, Laboratory Technicians and Managers, Clinical Biochemists, Analytical Chemists

Research areas: Lipidomics, lipid biology, metabolomics, biochemistry, molecular biology, biomedical research, proteomics, drug development, biomarker development, mass spectrometry, imaging

Why you should attend:
This webinar will illustrate how recent technology advancements now provide new opportunities, facilitating identification and quantification of over 400 molecular lipids in human plasma in less than 12 minutes, covering positive and negative polarities.

The presentation will be followed by an interactive Q&A session. This webinar will be available as a recording on-demand, soon after the live session.

Speakers:
Dr. Kim Ekroos
Head of Bioanalytics
Zora Biosciences Oy, Finland

Dr. Axel Besa
Manager Applications, EMEA
Pharmaceuticals & CRO and Metabolomics/Lipidomics
AB SCIEX

External linkRegistration is Free and only takes a few minutes of your time to fill in your details.


The 2nd Edition of the Proteomics Photo&Graphic Art Contest External linkis Open for Applications!

The application deadline is May 1 2012

Scientists and non-scientists can participate see External linkRegulation.

The 2012- Proteomics Photo & Graphic Art Contest and Exhibition seeks to explore the aesthetic qualities and potential artistic merit of images associated with Proteomics concept/research. The aim is to capture the general public attention to Proteomics as an important tool for understanding of the biological processes of organisms (from microorganisms to plants and man), including the physiological and pathological mechanisms that underlie health and disease.

An international Jury composed of members from the scientific and artistic communities will pre-select the best Top 20 works in competition. The best Top 20 images will be available for online voting from May 16 to July 11 2012. The images will be exhibited during the 2012-EuPA Meeting 2012, hosted by the British Society for Proteome Research (BSPR), at the Glasgow Royal Concert Hall, Glasgow, Scotland from Monday July 9 - Thursday July 12 2012, where participants will have the last opportunity to vote for their favorite image. The winner of the competition will be announced during the congress gala dinner, with media coverage.

The winner image will be awarded 1000€ and published as the cover of the special issue of the External linkJournal of Proteomics-Elsevier, dedicated to the External linkEuPA Scientific Meeting 2012

The 2nd edition of this Contest is promoted by External linkThe European Proteomics Association  (EuPA) and the External linkBritish Society for Proteome Research (BSPR) in collaboration with the Portuguese Proteomics Association (External linkREDE-PROCURA) and 'Associação Viver a Ciência' (External linkVAC).


Otto Warburg Medal for Alexander Varshavsky

Otto Warburg Medal for Alexander VarshavskyBiochemist and geneticist Alexander Varshavsky (California Institute of Technology, USA), who was born in Moscow and has lived in the USA since 1977, has been awarded the Otto Warburg Medal of the German Society for Biochemistry and Molecular Biology (GBM). That medal is considered to be the highest German award for biochemists and molecular biologists. Check the External link  BBA journals website for more details.


External linkAllosteric Regulation. Special Issue Edited by Gregory Grant

This volume will hopefully provide the reader with an appreciation of how far we have come since the term "allosteric" was first used in 1961 to describe the regulation of enzyme activity by conformational modulation. Also, this volume will likely provide a sense of how far we still have to go to truly understand the process at the molecular level in all of its facets.


BBA General Subjects Poster award at SASBMB/FASBMB meeting in South Africa

BBA General Subjects Poster award at SASBMB/FASBMB meeting in South AfricaAt a well attended South African Society for Biochemistry and Molecular Biology conference organized by Drs. Theresa Coetzer, Marco Weinberg, Alexio Capovilla and coworkers from the University of the Witwatersrand, three poster prizes were awarded in a grand finale - the first prize being the Elsevier/BBA General Subjects prize, with two second and third prizes being awarded by the organizers themselves.  The BBA General Subjects prize went to Reyna Deeya Ballim, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, South Africa, for the following poster:
"The Ulnar-Mammary Syndrome Gene, TBX3, is a Direct Target of the Retinoic Acid Signalling Pathway, which Regulates its Expression During Mouse Limb Development" by Reyna Deeya Ballim, Cathy Mendelsohn, Virginia E. Papaioannou and Sharon Prince.

Congratulations!


Irene Lee - new executive editor BBA Proteins and ProteomicsNew Executive Editor BBA Proteins and Proteomics:

The Publisher gratefully acknowledges the excellent role and support provided by Paul Cook as Executive Editor of BBA Proteins and Proteomics for so many years. We are happy to announce we found an enthusiastic successor, Irene Lee, who started January 1st in her new role. Her research interests include enzymology of proteases, kinases, ATPases, amine oxidases and polymerases.

Irene Lee:
Irene Lee received her undergraduate degrees in Chemistry and Biology at the University of Toledo, Ohio. She then conducted her graduate work with Stephen J Benkovic at the Pennsylvania State University, University Park, PA on screening and developing antibodies that catalyze amide bond hydrolysis; she received her Ph.D. in 1995. She was then employed as a postdoctoral research associate in the Benkovic lab to study the mechanism of a cell-cycle regulated DNA methyltransferase (CcrM) that has been implicated by genetic studies to be an endogenous substrate of Lon protease. She joined the Department of Chemistry at Case Western Reserve University in 1998 and is currently an Associate Professor in the department. Her research interests entail enzymology of proteases, kinases, ATPases, amine oxidases and polymerases.  Additionally structure-activity studies of synthetic molecules that are designed as modulators or activity probes of the aforementioned enzymes also constitute a major research focus.  It is anticipated that information generated from these studies will be used to advance our understanding of enzyme catalysis in the context of their physiological functions in cells.


LIPID MAPS and Elsevier Launch Lipid Structures App on SciVerse Applications

Click here to see the recent press release. The application can be downloaded by all ScienceDirect subscribers  – see the External link  app web site and click on Add application buttons.Lipid Maps

This application identifies lipid names or synonyms in an online article and provides the user with supporting information on that particular lipid in a popup which displays the structure and other key information for that molecule as represented on the External link  LIPID MAPS™ website. Information includes common and systematic names, formula, exact mass, InChIKey, classification hierarchy and links to other public databases. A panel in the side-bar also provides a convenient listing of lipid molecules in the article along with snippits from the text where the structure occurs.

The app developer, Eoin Fahy, and colleagues recently wrote an informative External link  article on Lipid Maps in a BBA special titled " External link  Lipidomics and Imaging Mass Spectrometry ".




17th European Bioenergetics Conference (EBEC 2012) – Freiburg, Sept 15 – 20, 2012

The 17th European Bioenergetics Conference (EBEC 2012) will be held September 15 to 20, 2012 in Freiburg. Approximately 500 participants will attend, present their work and discuss their scientific achievements in the area of bioenergetics. The conference will cover topics such as: Electron transport and proton pumps, Photosynthesis, ATP synthase, Membrane transporters, Uncoupling proteins, Ion channels, Bacterial membrane proteins, Mitochondrial medicine, Mitochondria and neurodegeneration, Cell physiology and mitochondrial signalling, Mitochondrial structure and dynamics, Reactive oxygen species and ageing, Mitochondrial proteomics and some more.

Details of the meeting, speakers and arrangements are posted on our website External link  http://www.ebec2012.uni-freiburg.de/. All lectures and poster abstracts will be published in a Special Issue of Biochimica et Biophysica Acta (Bioenergetics) as in previous EBECs.


BBRC Mini-reviews on Autophagy
Two recently published mini-reviews in BBRC, our ultra-rapid publication journal, focus on the important topic of autophagy and cell death mechanisms in relation to therapeutics:

For more details on BBRC External link  editors, visit the journal External link  website.



Bacteria are 'cool'
This year, the External link  universities of Amsterdam, VU Amsterdam and UvA University, join forces to participate as a team in the External link  iGEM (international Genetically Engineered Machine) competition. Seven motivated students of both Amsterdam Universities get the unique opportunity to participate in the synthetic biology competition organized by MIT.

IGEM is an international synthetic biology competition for undergraduate students. The participating students should be as creative to design a feasible project, in which the project is performed during the summer. The designed "BioBricks" - pieces of DNA with a particular function - in the project will enrich the open source database of iGEM. The project of the Amsterdam iGEM team concerns developing IcE. Coli, which are E. coli bacteria that are more resistant to low temperatures. Potential applications of IcE coli are the production of biofuels and cleaning oil spills.


Progress in Lipid Research editor presents a PLR Young Speaker Award at External link52nd International Conference on the Bioscience of Lipids

Progress in Lipid Research editor and ICBL President Guenther Daum (right on photo; left George Carman) recently presented a PLR Young Speaker Award, to Malgorzata Gutkowska-Stronkowska from Warsaw whose excellent contribution was selected from the many outstanding contributions submitted for the conference.

The special issue of Chemistry and Physics of Lipids (editor-in-chief Richard Epand), vol 164 supplement 1 containing abstracts from the External link  52nd International Conference on the Bioscience of Lipids is now available External link  online


EuPA 2012 – Glasgow - New Horizons and Applications of Proteomics

CHANGE OF DATES – NOW TAKING PLACE Monday 9th – Thursday 12th July 2012.

2012 will also be the Diamond Jubilee of the accession to the throne by H. M. Queen Elizabeth II. Earlier this year we learned that the celebration of this event will be held on the first week-end in June, and that the May public holiday will be moved to Monday 4th June. This will be followed by an additional public holiday on Tuesday 5th June.

To avoid impact, we are pleased to be able to announce that the meeting will now take place from Monday 9th – Thursday 12th July 2012. All other aspects of the meeting, including the venue, scientific topics and social programme are unchanged.

The local organising committee regret that we had no alternative but to make this decision.

On behalf of the organizers,
Josie Beeley (Convener, Local Organising Committee.)
David O'Connor (President BSPR).
External link  www.eupa2012.org
eupa2012@mci-group.com


BBA Lipids Lectureship – awarded to Jean Vance

Elsevier and the External linkMolecular and Cell Biology of Lipids section of BBA sponsored the travel and registration costs of an invited lecturer to the 2011 Gordon Research Conference on the Molecular and Cellular Biology of Lipids held in Waterville Valley, NH USA from July 17-22. The lecturer this year was Jean Vance, Ph.D., Professor of Medicine at the University of Alberta, Edmonton, Canada. Dr. Vance was honored for her contributions to phospholipid and cholesterol metabolism in mammalian cells. The title of her presentation was "Cholesterol trafficking in the brain and in Niemann-Pick C disease". Pictured with Dr. Vance (center) are William Dowhan, Ph.D., outgoing executive editor, and Suzanne Jackowski, Ph.D., incoming executive editor of the Journal. Rudi Zechner, Ph.D. is the continuing executive editor. Judy Storch, Ph.D., Professor of Nutritional Sciences at Rutgers University, was the organizing chair of this year's meeting.

External linkIn vitro fertilization: Four decades of reflections and promises

This article outlines the development and progression of IVF from its infancy to the refined and broadly utilized technology offered to patients today. The authors describe the evolution of the field and the current state of IVF, including its current technological and social challenges. The article is a tribute to Robert Edwards who was awarded the Nobel Prize in Medicine for his exceptional accomplishments in this specific and rewarding field of modern medicine.

Published in External linkBBA General Subjects – publishing papers of general significance.

BBA sets new records – impressive increase in Impact Factors

BBA would like thank all authors, reviewers, and (guest) editors who contributed to the increase in impact factors of all BBA's sections publishing original research, resulting in a record high average score of 5.125 for the nine sections.
For the full list of our External linkBiochemistry titles, click to this informative overview.


ISMB / BioDBCore workshop on External linkUnifying Bio-Resource Descriptors, Vienna, July 18th, 2:30 PM.

Organisers: Dawn Field, NERC, NEBC, UK; Pascale Gaudet, Swiss Institute of Bioinformatics, Switzerland; Susanna-Assunta Sansone, University of Oxford, UK.

The workshop will bring together developers, curators, journal editors and researchers to discuss the growing number of (closely related) efforts emerging around catalogues of tools, databases, related data and publications. The focus of the workshop is a straw-man uniform system for describing bio-resources, in particular, indicating in a consistent manner which community-defined standards, such as minimal information checklists, terminologies and exchange formats, they implement. Such a uniform system will i) assist the research and bioinformatics communities to locate and access information distributed in bio-resources, and ii) inform journal editors and funding agencies implementing data preservation, management and sharing policies, when they recommend or require that certain standards are met and that data are deposited in public databases. If you are going to ECCB/ISMB in Vienna, please join us: External linkhttp://www.iscb.org/ismbeccb2011-program/workshops#w4.

Authoritative Review (25 printed pages)

External linkEther lipids  - by Carlos D. Magnusson and Gudmundur G. Haraldsson

Highlights

  • This review article provides a comprehensive and up to date review on the naturally occurring 1-O-alkyl-sn-glycerol ether lipids and their methoxylated congeners, 1-O-(2′-methoxyalkyl)-sn-glycerols.
  • These are biologically active compounds, ubiquitously found in nature as diacyl glyceryl ether lipids and phosphoether lipids.
  • The occurrence and distribution of these compounds in nature are extensively reviewed, their chemical structure and molecular variety, their biosynthesis and chemical synthesis and, finally, their various biological effects are described and discussed.

Ref. External link  Chemistry and Physics of Lipids External linkVolume 164, Issue 5, July 2011, Pages 315-340 (Editor-in-Chief Richard Epand)


Editor Helmut Meyer presents BBA Young Investigator Award to Juli-Maria Burkhart

During the recent 18. External linkArbeitstagung "Mikromethoden in der Proteinchemie" the BBA Young Investigator Award was presented to Juli-Maria Burkhart from the ISAS-Institute in Dortmund. All in all, the organizers presented 6 prizes which were sponsored from participating companies. 16 young scientist applied for one of these prizes and 8 of them were chosen for an 12 min oral presentation. The auditorium voted then who gave the best presentation with the best performance. All of the young scientist were quite nervous but likewise very excellent when they presented their work and can be congratulated on their performance.

The 19. Arbeitstagung "Mikromethoden in der Proteinchemie" will be held in Bochum in 2012, organized by Prof. Dr. Helmut E. Meyer, Executive Editor BBA Proteins and Proteomics, and Direktor External linkMedizinisches Proteom-Center, Bochum

BBA Proteins and Proteomics – for submissions in proteomics and protein bioinformatics, use our External linke-submission site.


New organization in plant proteomics – join now!

INPPO is a global plant proteomics organization to properly organize, preserve and disseminate collected information on plant proteomics.
The broad goals of INPPO are to i) achieve the establishment of complete proteomes from plants, ii) exploit them to address critical biological questions (such as plant, seed and crop improvement), iii) achieve better basic understanding of plant systems in interaction with their biotic and abiotic environments, and iv) develop applications aimed toward sustainable agriculture, environmental biotechnologies, healthier and safer plants, new plant materials, nutraceuticals and more. Ten initiatives of INPPO are outlined in a recent External link  paper in PROTEOMICS along with how to address them in multiple phases. As our vision is global, we sincerely hope the scientific communities around the world will come together to support and join INPPO.

To join, fill in your External linkdetails.

BBRC welcomes new Bioinformatics Editor

BBRC – the most rapid journal in the Life Sciences – is pleased to welcome Professor Anna Tramontano from Italy as an Editor handling Bioinformatics papers. A quick glance at her curriculum shows we could not have wished for a more suitable candidate. The journal looks forward to many more high quality submissions in the areas of computational biology and bioinformatics that merit rapid publication. To submit your next paper to Anna Tramontano, please visit our External link  submission website.

Prof. Anna TRAMONTANO (IT) - Current position: Chair Professor of Biochemistry in the "Sapienza" University in Rome.

Anna Tramontano was trained as a physicist but she soon became fascinated by the complexity of biology and by the promises of computational biology. After working at the Biocomputing Programme of the European Molecular Biology Laboratory in Heidelberg, Germany, she moved back to Italy to work in the Merck Research Laboratories. Later she returned to the academic world as a Chair Professor of Biochemistry in the "Sapienza" University in Rome where she continues to pursue her scientific interests on protein structure prediction and analysis. She is a member of the European Molecular Biology Organization (EMBO) and of the Scientific Council of Institute Pasteur - Fondazione Cenci Bolognetti. She is a member of the Scientific Advisory Boards of several prestigious Institutions including the Institute Pasteur - Fondazione Cenci Bolognetti, the European Bioinformatics Institute (EBI), the MPI for Molecular Genetics in Berlin, the Swiss Institute for Bioinformatics, the Centro Nacional de Biotecnología in Madrid and the International Institute of Molecular and Cell Biology in Warsaw. Anna is currently a Member of the Scientific Council of the European Research Council (ERC). She has been vice President of the International Society for Computational Biology (about 1500 members) and part of the steering committee of the European networks, BioSapiens and Elixir. She has received, among others, the Tartufari Prize of the Accademia dei Lincei, the KAUST Global Research Partnership award, the special Government Prize for Natural Sciences and the Marotta Prize of the National Academy of Science.


Highlighted article on MALDI protein profiling in Journal of Proteomics

The first decade of MALDI protein profiling: A lesson in translational biomarker research (External link  review)

MALDI protein profiling has identified several important challenges in omics-based biomarker research. First, research into the analytical performance of a novel omics-platform of potential diagnostic impact must be carried out in a critical manner and according to common guidelines. Evaluation studies should be performed at an early time and preferably before massive advancement into explorative biomarker research. In particular, MALDI profiling underscores the need for an adequate understanding of the causal relationship between molecular abundance and the quantitative measure in multivariate biomarker research. Secondly, MALDI profiling has raised awareness of the significant risk of false-discovery in biomarker research due to several confounding factors, including sample processing and unspecific host-response to disease. Here, the experience from MALDI profiling supports that a central challenge in unbiased molecular profiling is to pinpoint the aberrations of clinical interest among potentially massive unspecific changes that can accompany disease. The lessons from the first decade of MALDI protein profiling are relevant for future efforts in advancing omics-based biomarker research beyond the laboratory setting and into clinical verification.


2nd Sir Michael Berridge Lecture – by Katsuhiko Mikoshiba

The Sir Michael Berrigde lectureship was inaugurated in 2008 at the 10th Symposium of the ECS Society in Leuven, Belgium, to celebrate the 25th anniversary of the seminal paper of Berridge and his colleagues published in Nature to demonstrate the IP3-dependent calcium release from a nonmitochondrial intracellular store which later turned out to be the endoplasmic reticulum. The first lecture was delivered by Chakashi Toyoshima in Leuven who solved the structural principles of the activation cycle of the Ca2+ pump of the sarcoplasmic reticulum. Katsuhiko Mikoshiba (RIKEN Brain Research Institute, Hirosawa, Japan) who discovered the IP3 receptor gave the second Berridge lecture to close the symposium in Warsaw. He summarized the breath-taking amount of data he and his Lab collected over the years on the structure-function relationship of the IP3 receptor and its role in cell function and disease, only a few of them can be mentioned External link  here.

We are looking forward to the 3rd External link  ECS workshop 2011 in Seix, France, followed by the 12th ECS Calcium Meeting which is going to be organized by Marc Moreau and his colleagues in 2nd week of September 2012 in Toulouse, France.

A special issue containing papers from this conference can now be found online:

BBA Molecular Cell Research External linkVolume 1813, Issue 5 (May 2011)
11th European Symposium on Calcium
Edited by J. Haiech, C.W. Heizmann and J. Krebs

BBRC introducing Graphical Abstracts

BBRC – the number 1 journal in the field of Biophysics in the EigenFactor ™ score ranking, number of articles published and total cites – is now introducing optional  Graphical Abstracts to help the journal stay in its premier spot and optimally serve authors and readers.

A Graphical abstract is optional and should summarize the contents of the paper in a concise, pictorial form designed to capture the attention of a wide readership online. Authors must provide images that clearly represent the work described in the paper. Graphical Abstracts should be submitted as a separate file in the online submission system. Image size: Please provide an image with a minimum of 531 × 1328 pixels (h × w) or proportionally more. Preferred file types: TIFF, EPS, PDF or MS Office files. See www.elsevier.com/graphicalabstracts for examples.


BBA Proteins and Proteomics adds strength in Proteomics field with 3 new board members

BBA Proteins and Proteomics is pleased to announce the appointment of three additional
Editorial board members to strengthen expertise in this area:

Christian Stephan
Medizinisches Proteom Center, Ruhr-Universität Bochum, Bochum
Keywords:  Proteomics, Bioinformatics, Biostatistics, Software development, quantitative Proteomics

Albert Sickmann
Leibniz-Institut für Analytische Wissenschaften, Dortmund
Key Words: Bioanalytics, Protein Chemistry, System Biology, Mass Spectrometry, Posttranslational Modifications

Kai Stühler
Medizinisches Proteom Center, Ruhr-Universität Bochum, Bochum
Key Words:  Tissue Proteomics, Neurooncology, Mass Spectrometry, 2D-DIGE, PAGE, Neuroproteomics

The editors look forward to more External link  submissions in this area of growing importance.


Did you know... your submission may be checked! You can also check yourself now.

CrossCheck is an initiative started by CrossRef to help Publishers actively engage in efforts to prevent plagiarism. Although there are several plagiarism screening tools already available, they are not well-suited to filtering academic content simply because they haven't had access to the relevant full-text literature to screen against. CrossCheck changes this by creating and continuously growing a database of current and archival scholarly literature. Plagiarism prevention software provider iParadigms has announced a new service that provides individual authors, researchers and freelance writers access to the company's iThenticate solution. The new service, currently available at External link  http://research.ithenticate.com, allows individuals to cross-reference their manuscripts against a massive database of scholarly material in the STM fields with the goal of vetting their material, ensuring that any non-original content is accurately and comprehensively cited before submission.

Our Executive Editors now use this tool to help identify cases of scientific misconduct.


External link  Archives of Biochemistry and Biophysics – Latest Special Issue now online!

P450 Catalysis Mechanisms
Edited by F. Peter Guengerich
External link  Volume 507, Issue 1,  Pages 1-204 (1 March 2011)

This special issue of Archives of Biochemistry and Biophysics on catalytic mechanisms is dedicated to Professor Minor J. Coon, of the University of Michigan Medical School, on the occasion of his 90th birthday (July 29, 2011). His seminal contributions in the cytochrome P450 (P450) field over a period of three decades have been truly remarkable

Journal of Proteomics

Journal of Proteomics adds strength in Bioinformatics

The Journal of Proteomics is pleased to announce the appointment of External link  Akhilesh Pandey as new Executive Editor covering Bioinformatics, replacing Peter Hojrup whose term has come to an end. We are grateful for Peter's contributions in the past few years.

The editorial board has also be strengthened with expertise in this area with the addition of several new board members:

External link  Michael McCoss - University of Washington, Dept of Genome Sciences, Seattle, USA
External link  Pavel Pevzner  -  Dept of Computer Science & Engineering, UCSD, La Jolla, USA
External link  Harsha Gowda - Institute of Bioinformatics, Bangalore, India
External link  Hanno Steen, Children's Hospital Boston, USA

 

The editors look forward to more External link  submissions in this area of growing importance.


Markus Wenk

Progress in Lipid Research announces new Executive Editor: Dr. Markus R. Wenk

The prestigious, high impact review journal Progress in Lipid Research is pleased to announce the appointment of Markus Wenk as Executive Editor of the journal. Markus Wenk will replace two editors, Dennis Voelker and Gerrit van Meer, who just retired at year end and whose major contribution to the success of the journal is greatly acknowledged. We are pleased to welcome such a distinguished expert in the growing field of lipidomics to the board of the journal and look forward to many interesting and authoritative review articles in the years to come. Your suggestions for new topics to be covered are welcome at any time. Please feel free to contact one of the editors: John Harwood (Cardiff), Masahiro Nishijima (Tokyo) or Markus Wenk (Singapore).
Contact details: Markus R. WENK Associate Professor, National University of Singapore, website: External link  http://www.lipidprofiles.com
MAJOR RESEARCH INTEREST: Application of lipid profiling ("lipidomics") as a novel and independent approach for the systems level scale analysis of biological systems.


External link  Developments for a Growing Japanese Patient Population: Facilitating New Technologies for Future Health Care

The next generation of personalized drugs for targeted and stratified patient treatment will soon be available in major disease areas such as, lifestyle-related cancers, especially lung cancers with the highest mortality including a predisposing disorder chronic obstructive pulmonary disease, cardiovascular disease, and other diseases. Mass spectrometric technologies can provide the "phenotypic fingerprint" required for the concept of Personalized Medicine.


Structured Digital Abstacts

FEBS Letters is the first journal to link novel protein-protein interactions that are described in the manuscript directly to a molecular interaction database. Find out more about External link  Structured Digital Abstacts.

Nature Biotechnology also published an article this year related to structured digital abstracts representations titled External link  'The FEBS Lettters / BioCreative II.5 experiment: making biological information accessible'.



Highlighted Review

External link  Biopersistent fiber-induced inflammation and carcinogenesis: Lessons learned from asbestos toward safety of fibrous nanomaterials

Nano-sized durable fibrous materials such as carbon nanotubes have raised safety concerns similar to those raised by asbestos. However, the mechanism by which particulates with ultrafine structure cause inflammation and ultimately cancer (e.g. malignant mesothelioma and lung cancer) is largely unknown. This is partially because the particulates are not uniform and they vary in a plethora of factors. Such variances include length, diameter, surface area, density, shape, contaminant metals (including iron) and crystallinity. Various kinds of fibers were evaluated with different cells, animals and methods. The aim of this review is to concisely summarize previous reports from the standpoint that activation of macrophages and mesothelial injury are the two major mechanisms of inflammation and possibly cancer.


External link  BBRC EDITOR WINS THE NENCKI AWARD 2010

Professor Ernesto Carafoli (Italy/Switzerland) was awarded the second edition of the Nencki Prize 2010.

Professor Carafoli is a world-renowned specialist in the role of calcium as signalling molecule in cell metabolism as well as in Ca2+ transport across biological membranes. He is also expert in calcium homeostasis in the cell and the role of Ca2+ in the regulation of cellular metabolism. Carafoli was one of the first to discover energy-dependent accumulation of calcium within mitochondria. Then, he studied the calcium pump of the plasma membrane and contributed to its isolation, purification and characterization as an enzyme (“Ca2+-pumping ATPase”). More recently, Ernesto Carafoli became involved in studying various aspects Ca2+ function as signalling molecule, in particular in the nucleus.

External link  Read the full announcement


External linkFEBS Telomeres Special Issue
The Special Issue features in-depth reviews of telomere biology and DNA repair.
Edited by Jan Karlseder and Wilhelm Just
Volume 584, Issue 17, Pages 3673-3838 (10 September 2010)


BBA Reviews on Cancer

BBA Reviews on Cancer expands in the field of BIOINFORMATICS – Jill Mesirov joins as Editor

BBA Reviews on Cancer is pleased to announce the appointment of Jill Mesirov on the Board of Editors, to reinforce the journal’s expertise in this important growing area.

Jill Mesirov is associate director and chief informatics officer at the Broad Institute of MIT and Harvard, where she directs Computational Biology and Bioinformatics. Jill is also a member of the David H. Koch Institute for Integrative Cancer Research at MIT and adjunct professor of bioinformatics at Boston University. Her current research interest is computational biology with a focus on algorithms and analytic methodologies for pattern recognition and discovery with applications to cancer genomics, genome analysis and interpretation, and comparative genomics. In addition, Jill is committed to the development of practical, accessible software tools to bring these methods to the general biomedical research community.

The External link  journal welcomes reviews on cancer bioinformatics.


Archives of Biochemistry and Biophysics

Structural data - Revised Guide to Authors for ABB:
 

Archives in Biochemistry and Biophysics has revised its External link  Instructions to Authors to include the following requirement:

For papers describing structures of biological macromolecules, the atomic coordinates and the related experimental data (structure factor amplitudes/intensities and/or NMR restraints) must be deposited at a member site of the Worldwide External link  Protein Data BankExternal link  RCSB PDB,External link  MSD-EBI,External link  PDBj, or External link  BMRB. External link  READ COMPLETE REVISED INSTRUCTIONS

All authors publishing structural data are requested to strictly adhere to these guidelines, to support interactive structures as a future enhancement of the online journal.

 

Journal of Proteomics Graphical Abstracts in Journal of ProteomicsExternal linkrevised instructions to authors

 

BBA Proteins and Proteomics

External link  Protein Bioinformatics - submissions are welcome

BBA - Proteins and Proteomics has revised its Aims & Scope statement to more explicitly welcome manuscript submissions in the growing area of PROTEIN BIOINFORMATICS. Please find the revised scope statement below:

BBA's Proteins and Proteomics section covers protein structure conformation and dynamics, protein folding, protein-ligand interactions, enzyme mechanisms, models and kinetics, protein physical properties and spectroscopy, proteomics, and bioinformatics analyses of protein structure, protein function, or protein regulation.

Concise and comprehensive reviews of recent developments are considered for publication. However, authors are strongly advised to consult one of the Executive Editors before starting a review.

Journal e-submission site: External link  http://ees.elsevier.com/bbapro/

 

BBA Gene Regulatory Mechanisms

BBA Gene Regulatory Mechanisms - title change and call for submissions:

Given the changing landscape of the field, the emphasis of BBA Gene Structure and Expression has been redirected to BBA Gene Regulatory Mechanisms. This section now includes reports that describe novel insights into mechanisms of transcriptional, post-transcriptional and translational gene regulation. Special emphasis will be placed on papers that identify epigenetic mechanisms of gene regulation, including chromatin structure and its modification or remodeling. This section will also encompass mechanistic studies of regulatory proteins and protein complexes; regulatory or mechanistic aspects of RNA processing; regulation of expression by small RNAs; genomic analysis of gene expression patterns; and modeling of gene regulatory networks. Papers describing gene promoters, enhancers, silencers or other regulatory DNA regions will be accepted only if they present significant functional studies that illuminate novel features of gene regulatory mechanisms. We encourage scientists exploring the many facets of gene regulatory mechanisms to consider this refocused and revitalized section of BBA. We wholeheartedly welcome you to submit your latest research articles to BBA Gene Regulatory Mechanisms as an appropriate outlet for publication of exciting, innovative and significant advances. To submit, visit:   External link  http://ees.elsevier.com/bbagrm/

  • Charting a Course for a Successful Research Career

        External linkA Guide for Early Career Researchers - 120-page booklet for free!
        Click the link to get this 120-page booklet for free!

  • Figure Manipulation:

    BBA has added new text to its Guide to Authors to deal with figure manipulation. See also External linkORI's Forensic Tools for Quick Examination of Scientific Images and Plagiarism for more on this subject.




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