(BBA) - Gene Regulatory Mechanisms Chromatin in viral Gene Expression Volume 1799, Issues 3-4, (March-April 2010) Edited by P.M. Lieberman
This special focus edition of BBA hopes to highlight some of the most recent findings on how viruses interact with cellular chromatin. The aim is to provide a review and survey of the different virus systems and how each of these provides new insights into understanding chromatin regulation. One major goal is to highlight unique and specific mechanisms tailored for the special needs of particular viruses. This will provide virologists and non-virologists with a fresh perspective on how chromatin can be manipulated to promote gene expression, DNA replication, genome stability, and genetic transmission. A second and equally important goal is to identify the common mechanisms and strategies used by family of viruses to achieve efficient propagation of their genomes. And a third aim is to identify aspects of cellular chromatin that may function as anti-viral defense mechanisms, and how viruses subvert this process.
Paul M. Lieberman
Paul M. Lieberman, Ph.D., Professor of Gene Expression and Regulation Program at the Wistar Institute in Philadelphia and Adjunct Professor in the Department of Microbiology at the University of Pennsylvania, School of Medicine. Dr. Lieberman received his Ph.D. in 1989 at the Johns Hopkins University, School of Medicine. He received a post-doctoral Fellowship with the American Cancer Society and a Leukemia-Lymphoma Society Special Fellow Award in the laboratory of Dr. Arnold Berk at University of California, Los Angeles. Dr. Lieberman’s research focuses on the gene regulatory mechanisms controlling gammaherpesvirus latency and the role of chromatin in viral and cellular genome maintenance. Dr. Lieberman has recently been named the Director of the Center for Chemical Biology and Therapeutic Medicine at the Wistar Institute where his team is developing small molecule inhibitors of gammaherpesvirus latency. Dr. Lieberman also teaches graduate level courses on Fundamental Virology and Eukaryotic Gene Expression.
Paul M. Lieberman
