BBA - Gene Regulatory Mechanisms - The 26S Proteasome: When degradation is just not enough!

BBA - Gene Regulatory Mechanisms

BBA - Gene Regulatory Mechanisms
External linkThe 26S Proteasome: When degradation is just not enough!
Edited by T.K. Archer
Volume 1809, Issue 2, Pages 65-156 (February 2011)

The focus of this short special edition is the emerging evidence that while playing a crucial role in protein degradation we are beginning to see an expansion in the repertoire of this important biochemical complex External link[11]. The edition consists of seven reviews and one original article that are grouped into three sections but as is evident upon reading the manuscripts, they are all highly interrelated.
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Yuval Shaked

Trevor K Archer Ph.D. is a Senior Investigator and Chief of the Laboratory of Molecular Carcinogenesis at the National Institute of Environmental Health Sciences, NIH. He received his Ph.D. from Queen's University in Kingston Ontario Canada, where he studied the hormonal regulation of apolipoprotein biosynthesis in human cells. Following a postdoctoral fellowship at the National Cancer Institute in Bethesda, he took a joint appointment at the department of Biochemistry and department of Obstetrics & Gynecology at the University of Western Ontario where he made significant contributions to the role of chromatin remodeling proteins in nuclear receptor mediated transcription. The focus of his current research is directed to understand the contributions that chromatin remodeling proteins, 26S proteasome, pluripotency factors, mirRNAs and nuclear receptors make to regulate the transcriptional response to endogenous and environmental signals.


  
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