Gold Standard Re-launches ToxED Clinical Toxicology Poisoning and Drug Overdose Reference

New ToxED Meets Clinicians’ Need for Detailed, Life-Saving Overdose Information at the Point-of-Care

TAMPA, Fla., October 30, 2008 -- Setting a new standard for clinical toxicology poisoning and overdose references, Gold Standard Inc. has re-launched ToxED. The newly updated and revised electronic clinical toxicology reference addresses clinicians’ need for quick access to concise and comprehensive information at the point-of-care for the diagnosis and treatment of poisonings, drug overdoses, and exposure to chemicals and hazardous waste.

For the month of November, Gold Standard is offering a free electronic “Open House” to showcase the new version of ToxED. Just visit www.ToxED.com to register.

“ToxED is a crisp, concise, detailed, current and clinically relevant online resource designed to help clinicians get the information they need to support clinical care,” said Michael W. Shannon, M.D., MPH, the Medical Editor-in-Chief of ToxED and co-chair of the ToxED Board. Dr. Shannon is also Chief Emeritus, Division of Emergency Medicine at Children’s Hospital, Boston, and a Professor of Pediatrics at Harvard Medical School. “No other source in toxicology delivers information and insight of comparable timeliness and quality delivered in an easy-to-navigate and access format.”

More than 2.4 million poisonings were reported to the American Association of Poison Control Centers in 2005, and approximately 23 percent of those cases required treatment in a healthcare facility. Nearly 1,300 were fatal. On average, poison control centers handle one poison exposure every 14 seconds, and 53 percent of poison exposures occur in children under the age of six.

The first version of ToxED, introduced in 2006, offered clinicians limited insight into the basis of a treatment recommendation or how patients were responding on a physiological or molecular level. In contrast, this new version of ToxED is based on the highly authoritative toxicology manual by Haddad and Winchester, Clinical Management of Poisoning and Drug Overdose, published by Elsevier, the leading publisher of medical and scientific literature.

Clear, Concise, Efficient
Transformed into an efficient online tool with easy drop-down navigation and quick summaries, ToxED now offers clinicians enough information to save patients’ lives at the point-of-care, along with detailed but accessible and actionable treatment recommendations, sources and rationales.

ToxED bests several of its online and print toxicology competitors, which often required clinicians to wade through highly dense information to find a specific answer to a poisoning or exposure case. For example, a search on aspirin done within a competitor’s resource might yield 35-50 fairly atypical case examples of individuals who suffered from aspirin overdoses.

“These interesting but atypical cases tend not to meet clinicians’ needs and require an extensive amount of time to search and review.” said Dr. Shannon. “A clinician attempting to treat a 70-year-old man with as aspirin level of 85 wants reasonable step-by-step guidance on what to do, not a unwieldy treatise on everything that could possibly happen to a patient.”

Unique Plant, Mushroom Database
Among the most unique features of ToxED is its plant and mushrooms database. Often burdened with having to search for case reports on people who may have eaten poisonous berries, for example, clinicians can now consult ToxED to retrieve specific, actionable advice, including a picture of the berry, a description of the toxin and its effects and easy-to-follow treatment recommendations.

Divided into three sections focused on emergency management principles, specific agents and treatments, and environmental and occupational toxicology, ToxED includes the following features:

§ Material Safety Data Sheets and information from the Centers for Disease Control and Prevention (CDC), Environmental Protection Agency (EPA), Occupational Safety and Health Administration (OSHA) and the National Library of Medicine (NLM)
§ Drug IDentifier tool that identifies tablets and capsules based on marking/imprint, color and shape with full-color digital images of drug products for visual verification
§ Links to MD Consult, First Consult and Gold Standard's Clinical Pharmacology electronic drug information and medication management reference
§ Guidance on how to treat poisonings and drug overdoses, with discussions of decontamination, enhanced elimination, patient disposition, and pediatric patients
§ Explorations of drug overdoses and poisons, including toxic dose, clinical presentation, diagnosis and treatment
§ Descriptions of therapeutic drugs and antidotes, including pharmacology, indications, adverse reactions, drug interactions, recommended dosage and formulation information
§ Approaches to hazardous materials incidents, evaluation of occupational exposures, and the toxic effects, physical properties and workplace exposure limits of more than 500 common industrial chemicals

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About Gold Standard
Based in Tampa, Gold Standard is a leading developer of drug information databases, software and clinical information solutions. The Company's products are developed by a staff of highly trained professionals with extensive experience in pharmacy practice, electronic publishing and software development. Customers include more than 1,000 hospitals, the nation's largest retail pharmacy chains and consultant pharmacy organizations, state and federal agencies, the country's top pharmacy and medical schools, leading health information websites, and hundreds of thousands of healthcare professionals and consumers worldwide. Gold Standard's parent company, Elsevier, is a world-leading publisher of scientific, technical and medical information products and services with more than 7,000 employees in over 70 offices across 24 countries. To learn more about Gold Standard, visit www.goldstandard.com or call +1`(800) 375-0943.

About Elsevier

Elsevier is a world-leading provider of information solutions that enhance the performance of science, health, and technology professionals, empowering them to make better decisions, deliver better care, and sometimes make groundbreaking discoveries that advance the boundaries of knowledge and human progress. Elsevier provides web-based, digital solutions — among them ScienceDirect, Scopus, Elsevier Research Intelligence,and ClinicalKey—and publishes over 2,200 journals, including The Lancet and Cell, and over 25,000 book titles, including a number of iconic reference works.

The company is part of Reed Elsevier Group PLC, a world leading provider of professional information solutions in the Science, Medical, Legal and Risk and Business sectors, which is jointly owned by Reed Elsevier PLC and Reed Elsevier NV. The ticker symbols are REN (Euronext Amsterdam), REL (London Stock Exchange), RUK and ENL (New York Stock Exchange).

Media Contact:
Tom Reller
Elsevier
+1 212 462 1912
t.reller@elsevier.com