2011 Nobel Prize Medicine Articles

Professor Ralph M. Steinman, Professor Jules A. Hoffmann and Professor Bruce A. Beutler


Most Cited Articles Professor Ralph M. Steinman has published with Elsevier

Ralph Steinman

Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
Cell, 2010, 143 (3) pp 416-429, Cheong, C., Matos, I., Choi, J-H., Dandamudi, D.B., Shrestha, E., Longhi, M.P., Jeffrey, K.L., Anthony, R.M., Kluger, C., Nchinda, G., Koh, H., Rodriguez, A., Idoyaga, J., Pack, M., Velinzon, K., Park, C. G., Steinman, R.M.

Dendritic Cells In Vivo: A Key Target for a New Vaccine Science
Immunity
, 2008, 29 (3), pp.319-324, Steinman, R.M

Dendritic cells in transplantation - Friend or foe?
Immunity, 2001, 14 (4), pp. 357-368, Lechler, R., Ng, W.F., Steinman, R.M.

Dendritic cells: Specialized and regulated antigen processing machines
Cell
, 2001, 106 (3), pp. 255-258, Mellman, I., Steinman, R.M.

Antigen capture, processing, and presentation by dendritic cells: Recent cell biological studies
Human Immunology, 1999, 60 (7), pp. 562-567, Steinman, R.M., Inaba, K., Turley, S., Pierre, P., Mellman, I.

Virus replication begins in dendritic cells during the transmission of HIV-1 from mature dendritic cells to T cells
Current Biology, 1999, 9 (1) pp.21-29, Granelli-Piperno, A., Finkel, V., Delgado, E., Steinman, R.M.

Antigen processing for amateurs and professionals
Trends in Cell Biology, 1998, 8 (6), pp. 231-237, Mellman, I., Turley, S.J., Steinman, R.M.

Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood
Journal of Immunological Methods, 1996, Volume 196, pp. 121-135 
Bender, A., Sapp, M., Schuler, G., Steinman, R.M., Bhardwaj, N.

The cell surface of mouse dendritic cells: FACS analyses of dendritic cells from different tissues including thymus
Cellular Immunology
, 1989, 118 (1), pp. 108-125, Crowley, M., Inaba, K., Witmer-Pack, M., Steinman, R.M.


Most Cited Articles Professor Jules A. Hoffmann has published with Elsevier

Jules Hoffmann

The Drosophila Peptidoglycan Recognition Protein PGRP-LF Blocks PGRP-LC and IMD/JNK Pathway Activation
Cell Host and Microbe
, 2008, 3 (5) pp. 293-303, Maillet, F., Bischoff, V., Vignal, C., Hoffmann, J., Royet, J.

Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
Cell
, 2006 Volume 127 Issue 7 pp. 1425-1437, Marie Gottar, Vanessa Gobert, Alexey A. Matskevich, Jean-Marc Reichhart, Chengshu Wang, Tariq M. Butt, Marcia Belvin, Jules A. Hoffmann, Dominique Ferrandon

Sensing infection in Drosophila: Toll and beyond
Seminars in Immunology
, 2004, 16 (1), pp. 43-53, Ferrandon, D., Imler, J.-L., Hoffmann, J.A.

Notch signaling controls lineage specification during Drosophila larval hematopoiesis
Current Biology
, 2002. 12 (22), pp. 1923-1927, uvic, B., Hoffmann, J.A., Meister, M., Royet, J.

The Drosophila immune defense against Gram-negative infection requires the
Immunity
, 2002, 17 (5), pp. 575-581, Naitza, S., Rossé, C., Kappler, C., Georgel, P., Belvin, M., Gubb, D., Camonis, J., Hoffmann, J.A., Reichhart, J.-M.

Drosophila Immune Deficiency (IMD) Is a Death Domain Protein that Activates Antibacterial Defense and Can Promote Apoptosis
Developmental Cell
, 2001, Volume 1 Issue 4 pp.503-514, Philippe Georgel, Silvia Naitza, Christine Kappler, Dominique Ferrandon, Daniel Zachary, Candace Swimmer, Casey Kopczynski, Geoffrey Duyk, Jean-Marc Reichhart, Jules A. Hoffmann

Tissue-Specific Inducible Expression of Antimicrobial Peptide Genes in Drosophila Surface Epithelia
Immunity, 2000 Volume 13 Issue 5 pp 737-748, Phoebe Tzou, Serge Ohresser, Dominique Ferrandon, Maria Capovilla, Jean-Marc Reichhart, Bruno Lemaitre, Jules A. Hoffmann, Jean-Luc Imler

Signaling mechanisms in the antimicrobial host defense of Drosophila
Current Opinion in Microbiology, 2000, 3 (1), pp. 16-22, Imler, J.-L., Hoffmann, J.A.

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults
Cell, 1996, Vol 86 Issue 6 pp973-983, Bruno Lemaitre, Emmanuelle Nicolas, Lydia Michaut, Jean-Marc Reichhart, Jules A Hoffmann

Innate immunity of insects
Current Opinion in Immunology, 1995, 7 (1), pp. 4-10., Hoffmann, J.A.

Most Cited Articles Professor Bruce A. Beutler has published with Elsevier

Bruce Beutler

Toll-like receptors
Current Biology
, 2011, 21 (13), ppR488-R493, Eva Marie Y. Moresco, Diantha LaVine, Bruce Beutler

Hypomorphic Mutation in the Site-1 Protease Mbtps1 Endows Resistance to Persistent Viral Infection in a Cell-Specific Manner
Cell Host & Mircobe, 2011, 9 (3) pp 212-222, Daniel L. Popkin, D. L., Teijaro, J.R., Sullivan, B.M., Urata, S., Rutschmann, S., Torre, J.C. de la, Kunz, S., Beutler, B., Oldstone, M.

Intracellular Toll-like Receptors
Immunity
, 2010, 32 (3), pp305-315, Amanda L. Blasius, Bruce Beutler

Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway
Virology
, 2007, 362 (2), pp. 304-313, Georgel, P., Jiang, Z., Kunz, S., Janssen, E., Mols, J., Hoebe, K., Bahram, S., Oldstone, M.B.A., Beutler, B.

TRAF3: a new component of the TLR-signaling apparatus
Trends in Molecular Medicine
, 2006, 12 (5), pp 187-189, Kasper Hoebe, Bruce Beutler

Innate immunity: An overview
Molecular Immunology, 2004, 40 (12), pp. 845-859, Beutler, B.

Tlr4: Central component of the sole mammalian LPS sensor
Current Opinion in Immunology
, 2000, 12 (1), pp. 20-26, Beutler, B.

Analysis of Tlr4-mediated LPS signal transduction in macrophages by mutational modification of the receptor
Blood Cells, Molecules, and Diseases, 1999, 25 (5-6), pp. 328-338. Du, X., Poltorak, A., Silva, M., Beutler, B.

Special Delivery: Granulin Brings CpG DNA to Toll-like Receptor 9
Immunity
, 31 (4), pp 453-455, Moresco, EM. Y., Beutler, B.

Efficient T Cell Activation via a Toll-Interleukin 1 Receptor-Independent Pathway
Immunity, 24 (6), pp. 787-799, Janssen, E., Tabeta, K., Barnes, M.J., Rutschmann, S., McBride