2010 Nobel Prize Chemistry Articles
This year the Nobel Prize in Chemistry was divided between Richard F. Heck, Ei-ichi Negishi and Akira Suzuki "for palladium-catalyzed cross couplings in organic synthesis"
The Carbon atom forms the backbone of molecules in living organisms. However due to its stable structure, (carbon atoms do not easily react with one another), it has proved to be a challenge in the laboratory chemically to synthesize large molecules containing carbon.
According to a statement released by the Nobel Prize Committee, Palladium-catalyzed cross coupling solved that problem and provided chemists with a more precise and efficient tool to work with.
In recognition of the importance of their work, we are pleased to make the laureates’ key articles published with Elsevier freely available.
Richard F. Heck
Palladium catalyzed synthesis of aryl, heterocyclic and vinylic acetylene derivatives
Journal of Organometallic Chemistry, 1975, 93 (2), pp. 259-263; Dieck, H.A., Heck, F.R.
Palladium-catalysed cross-coupling reaction of alkynylzincs with benzylic electrophiles
Tetrahedron Letters, 2005, 46 (16), pp. 2927-2930. Qian, M., Negishi, E.-I.
Journal of Organometallic Chemistry, 1987, 334 (1-2), pp. 181-194; Negishi, E.-i., Takahashi, T., Akiyoshi, K.
A convenient synthesis of unsymmetrical bibenzyls homoallylarenes, and homopropargylarenes via palladium-catalyzed cross coupling
Tetrahedron Letters, 1983, 24 (36), pp. 3823-3824; Ei-ichi Negishi, Hajime Matsushita, Makoto Kobayashi, Cynthia L. Rand.
Highly selective synthesis of allylated arenes and diarylmethanes via palladium-catalyzed cross coupling involving benzylic derivatives
Tetrahedron Letters,1981, 22 (29), pp. 2715-2718; Ei-ichi Negishi, Hajime Matsushita, Nobuhisa Okukado
A new stereospecific cross-coupling by the palladium-catalyzed reaction of 1-alkenylboranes with 1-alkenyl or 1-alkynyl halides
Tetrahedron Letters, 1979, 20 (36), pp. 3437-3440; Miyaura, N., Yamada, K., Suzuki, A.
Journal of Organometallic Chemistry, 1982, 233 (2), pp. C13-C16; Miyaura N, Tanabe Y, Suginome H, et al.
A stereospecific synthesis of conjugated (E , Z)- and (Z , Z)-alikadienes by a palladium-catalyzed cross-coupling reaction of 1-alkenylboranes with 1-alkenyl bromides
Tetrahedron Letters, 1981, 22 (2), pp. 127-130; Miyaura, N., Suginome, H., Suzuki, A.