2009 Nobel Prize Physiology or Medicine Articles

This year the Nobel Prize in Physiology or Medicine was divided between three individuals

Elizabeth Blackburn, Jack Szostak and Carol Greider

"for the discovery of how chromosomes are protected by the enzyme telomerase"

 In recognition of the importance of their work,
we are pleased to make the laureates’ key articles published with Elsevier freely available.

Elizabeth H. Blackburn


Telomeres and telomerase: their mechanisms of action and the effects of altering their functions
FEBS Letters, Volume 579, Issue 4, Pages 859-862, 7 February 2005
E. Blackburn

Telomerase: Dr Jekyll or Mr Hyde?
Current Opinion in Genetics and Development, Volume 9, Issue 3, June 1999, pp. 368-373
Prescott, J.C., Blackburn, E.H

Two types of telomeric chromatin in Tetrahymena thermophila
Journal of Molecular Biology, Volume 280, Issue 3, Pages 327-344, July 1998
Cohen, P., Blackburn, E.H.

Increased telomerase activity and comprehensive lifestyle changes: a pilot study
The Lancet Oncology, Volume 9, Issue 11, November 2008, Pages 1048-1057
Dean Ornish, Jue Lin, Jennifer Daubenmier, Gerdi Weidner, Elissa Epel, Colleen Kemp, Mark Jesus M Magbanua, Ruth Marlin, Loren Yglecias, Peter R Carroll, Elizabeth H Blackburn

Cell aging in relation to stress arousal and cardiovascular disease risk factors
Psychoneuroendocrinology, Volume 31, Issue 3, April 2006, Pages 277-287
Elissa S. Epel, Jue Lin, Frank H. Wilhelm, Owen M. Wolkowitz, Richard Cawthon, Nancy E. Adler, Christyn Dolbier, Wendy B. Mendes, Elizabeth H. Blackburn

Carol W. Greider


Mammalian telomere dynamics: Healing, fragmentation shortening and stabilization
Current Opinion in Genetics and Development, Volume 4, Issue 2, April 1994, Pages 203-211
Greider, C.W.

Regulation of Telomere Elongation by the Cyclin-Dependent Kinase CDK1
Molecular Cell, Volume 24, Issue 3, 3 November 2006, Pages 423-432
Frank, C.J., Hyde, M., Greider, C.W.

Telomere end-replication problem and cell aging
Journal of Molecular Biology, Volume 225, Issue 4, 20 June 1992, Pages 951-960
Levy, M.Z., Allsopp, R.C., Futcher, A.B., Greider, C.W., Harley, C.B.

Current Opinion in Cell Biology, Volume 3, Issue 3, June 1991, Pages 444-451
Greider, C.W



Jack W. Szostak


Structure and Evolutionary Analysis of a Non-biological ATP-binding Protein
Journal of Molecular Biology, Volume 371, Issue 2, 10 August 2007, Pages 501-513
Mansy, S.S., Zhang, J., Kümmerle, R., Nilsson, M., Chou, J.J., Szostak, J.W., Chaput, J.C.

Constructing high complexity synthetic libraries of long ORFs using in vitro selection
Journal of Molecular Biology, Volume 297, Issue 2, 24 March 2000, Pages 309-319
Cho, G., Keefe, A.D., Liu, R., Wilson, D.S., Szostak, J.W.


Read more freely available groundbreaking research published in Cell