Books in Pharmacology

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Traditional Medicines and Natural Products as Preventive and Therapeutic Agents Against COVID-19

1st Edition
November 1, 2024
Nabeelah Bibi Sadeer + 1 more
English
Paperback
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eBook
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Traditional Medicines and Natural Products as Preventive and Therapeutic Agents Against COVID-19: A Promising Response to the Global Unprecedented Pandemic presents comprehensive coverage of the pharmacological effects of natural products on the prevention and treatment of COVID-19. Sections provide traditional medicine approaches and their potential to prevent and treat COVID-19 infection, including traditional Chinese, Ayurvedic, Persian, and Kampo medicine, alongside an overview of nutritional regimens and their therapeutic potential. Other sections cover natural molecules such as flavonoids, saponins, coumarins, alkaloids, terpenes, polysaccharides, and several microbial natural products of relevant action against viruses. Final chapters cover nanotherapeutic approaches.This is a valuable resource for researchers and academics in the fields of herbal medicine, pharmacology, pharmacognosy and for professionals in the pharmaceutical industries and anyone interested in natural products and their application for therapeutic purposes.

Progress in Medicinal Chemistry

1st Edition
Volume 63
November 1, 2024
Jonathan Bentley + 1 more
English
Hardback
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eBook
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Progress in Medicinal Chemistry, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Annual Reports on Medicinal Chemistry

1st Edition
Volume 62
October 1, 2024
Katherine Seley-Radtke
English
Hardback
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eBook
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Annual Reports in Medicinal Chemistry: STING, Volume 62 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. This release provides a compendium of information on newly approved drugs and compounds entering late-stage clinical trials, making it a valuable resource for graduate students pursuing research in medicinal chemistry

mRNA Therapeutics

1st Edition
September 1, 2024
Anya Hillery
English
Paperback
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eBook
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mRNA Therapeutics: Foundations, Innovations, and Clinical Applications summarizes the scientific development of mRNA vaccines that have revolutionized the way we treat disease. This approach has the potential to treat a wide range of diseases, including COVID-19, cancer, and infectious diseases. The first section of the book introduces mRNA vaccines, including their history, mechanism of action, and potential applications. The second section delves into the science of mRNA vaccines, covering topics such as the structure of mRNA, the delivery of mRNA to cells, and the immune response to mRNA vaccines.The third section discusses the future of mRNA technology, exploring potential applications such as cancer therapy, prevention of infectious diseases, and replacement of missing or damaged proteins. This is a valuable resource for scientists, researchers, and clinicians who are interested in the latest developments in mRNA technology. It is also a useful reference for students and professionals who are working in the fields of biotechnology, pharmaceutical science, and vaccine development.

The Discovery of New Medicines in Academia

1st Edition
Volume 100
August 1, 2024
Diane Peters + 1 more
English
Hardback
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eBook
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The Discovery of New Medicines in Academia, Volume 100 highlight examples of discoveries originating in academia that have been successfully translated into promising therapeutics that have advanced into clinical trials. Chapters in this release cover Design and Discovery of Itaconate prodrugs for Alopecia Areata, Hydroxyl-Dendrimer Delivery System for Neurological Disease, Development of allosteric modulators of G protein-coupled receptors for Psychiatric Disease, Targeting the constitutively active ERK1/2 signaling kinase for cancer, mRNA reprogramming of myeloid cells for tumor immunotherapy, Development of novel drugs targeting protein-protein interactions, and much more.Additional sections cover Neuro-steroids and analogs for the treatment of epilepsy, Development of inhibitors of eukaryotic translation, Discovery/development of antiviral, anticancer and/or anti-inflammatory agents, Discovery of novel anti-infective agents, Targeting proliferating cell nuclear antigen (PCNA) for cancer, and Implementation and Evolution of Quantitative Systems Pharmacology to Patient Digital Twins and Biomimetic Twins.

TRP Channels as Therapeutic Targets

2nd Edition
July 1, 2024
Arpad Szallasi
English
Hardback
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eBook
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TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use, Second Edition is a comprehensive reference on the roles of TRP Channels in health and disease states. Chapters are completely updated, withe new topics on TRP channels biology, the crystalline structure of TRP channels, targeting TRP channels for pain relief, the relationship with migraine, emerging pain targets, a comprehensive view of the role of TRP channels in respiratory diseases and COVID complications, anxiety relief, renal disease, arthritis, and therapeutic opportunities for thermal regulation. This is a great reference for broad segments of the scientific and medical community. Researchers working on TRP channel drug discovery will benefit from the overview of applications to conditions in specific organ systems. Clinicians interested in new drugs in the pipeline will also find this book helpful for biologic principles of action.

Quality Assurance Management

1st Edition
June 1, 2024
Gayathri De Lanerolle + 3 more
English
Paperback
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eBook
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Quality Assurance Management: A Comprehensive Overview of Real-World Applications for High Risk Specialties demonstrates how to best design and implement standard operating procedures (SOPs) to ensure protocol and regulation adherence. The book showcases similarities and differences between healthcare and academic quality assurance systems, resulting in counter-productivity and performance issues, in addition to regulatory inspection preparedness. It uses the processes and standards of the UK to demonstrate how to combine QA and research building into ‘building blocks’ that share a common pathway for effective project design, analysis and unbiased interpretation of collated data.This book fills a gap, providing original research in QA that especially focuses on specialist areas. It will be of use to research and clinical staff working in clinical research within healthcare, academia and industry.

Essentials of Translational Pediatric Drug Development

1st Edition
June 1, 2024
Elke Gasthuys + 3 more
English
Paperback
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eBook
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Essentials of Translational Pediatric Drug Development: From Past Needs to Future Opportunities provides integrated and up-to-date insights relevant for both translational researchers and clinicians active in the field of pediatric drug development. The book covers all key aspects from different stakeholder perspectives, providing a literature overview and careful reflection on state-of-the-art approaches. It will be an ideal guide for researchers in the field who are designing and performing high quality, innovative pediatric-adapted drug development by helping them define needs/challenges and possible solutions that advance and harmonize pediatric drug development.Despite the broad consensus that children merit the same quality of drug treatment as any other age group, children remain frequently neglected during drug research and development. Even with the adoption of multiple legislations addressing this problem, the lack of efficacy and safety data of marketed as well as newly developed drugs still remain in the pediatric population.

Advancement of Phenolic Acids in Drug Discovery

1st Edition
June 1, 2024
Naresh Kumar + 2 more
English
Paperback
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eBook
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Advancement of Phenolic Acids in Drug Discovery: Fundamental and Applications offers comprehensive coverage of the ADMET profiles of phenolic acids, their extraction method and prospects for drug design and development. Chapters overview phenolic acids and their characterization, discuss the role of phenolic acids in plant systems, present sources and detailed extraction methods of phenolic acids, and cover phenolic acid mechanisms of action as it relates to several key diseases and health conditions, including their role as antioxidant agents, anti-inflammatory and analgesic drugs, anti-microbial drugs, anti-viral drugs, anti-cancer drugs, diabetes and metabolic dysfunctions, neurological disorders, cardiovascular diseases. The book’s final chapters cover nanoscience aspects of phenolic acids, biomedical applications, and concludes with challenges and opportunities presented by phenolic acids. This is the ideal reference for researchers in the fields of drug development, both in academia and corporate settings. Researchers of related areas like food science and medicinal chemistry will also benefit from this in-depth profiling of therapeutical properties of phenolic acids.

The Diagnosis and Treatment of Protozoan Diseases

1st Edition
June 1, 2024
Tarun Kumar Bhatt
English
Paperback
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eBook
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The Diagnosis and Treatment of Protozoan Diseases discusses major protozoan diseases such as Malaria, Leishmaniasis, etc., including other clinically minor protozoan diseases. This book provides all essential information to professional researchers and medical personnel about the disease, causative organism, and their lifecycle, diagnostics, and treatments, including drugs and vaccine, resistance, and key points of future research. Infectious diseases are accountable for millions of deaths every year throughout the globe. Among them, significant contributors are protozoan parasites.Despite the many research group working on the various protozoan diseases, there are still major gaps to fill. The authors of this book have critically reviewed all the aspects of major protozoan diseases, their diagnostics, and treatments, including resistance.