Editor-in-Chief

  • Peter Wright

    The Scripps Department of Molecular Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92037, U.S.A.

    Email Peter Wright

Scientific Editor

Founding Editor

  • Sir John Kendrew †

Consulting Editor

  • Sydney Brenner

Associate Editors

  • Sheena E. Radford

    University of Leeds, Leeds, UK

    Protein folding and misfolding mechanisms

  • Michael J.E. Sternberg

    Imperial College London, London, UK

    Bioinformatics, systems biology, computational biology, webservers

  • Michael F. Summers

    University of Maryland, Baltimore County (UMBC), Baltimore, Maryland, USA

    Structural biology, RNA, proteins, structure, retroviruses, HIV

  • Moshe Yaniv

    Institut Pasteur, Paris, France

    Chromatin, epigenetic and gene expression; oncogenic viruses and cancer; cell growth control

Editorial Board Members

  • James M. Berger

    University of California at Berkeley, Berkeley, California, USA

    DNA replication, nucleic acid-dependent motors, chromosome organization and topology

  • Philip C. Bevilacqua

    Penn State University, University Park, Pennsylvania, USA

    RNA enzymology and structural genomics

  • James U. (Jim) Bowie

    University of California at Los Angeles (UCLA), Los Angeles, California, USA

    Membrane protein folding, function and design

  • Johannes Buchner

    Technische Universität München, Garching, Germany

    Molecular chaperones and protein quality control

  • Eric O. Freed

    National Cancer Institute (NCI), Frederick, Maryland, USA

    Virology, assembly and release of HIV-1/retroviruses

  • Judith Frydman

    Stanford University, Stanford, California, USA

    Molecular chaperones, chaperone networks, protein folding in cancer and neurodegenerative diseases, ribosome biogenesis

  • Mónika Fuxreiter

    University of Debrecen, Hungary

    Computational biology, intrinsically disordered proteins, protein dynamics, structure-function relationship

  • Ruben L. Gonzalez

    Columbia University, New York, New York, USA

    Ribosome structure and function, mechanism of protein synthesis, single-molecule biophysics

  • Max Gottesman

    Columbia University, New York, New York, USA

    Transcription elongation regulation in E. coli

  • Patrick R. Griffin

    The Scripps Research Institute, Jupiter, Florida, USA

    Metabolic control of inflammation and immunity, structural and chemical biology of enzymes and receptors, H/D exchange mass spectrometry

  • Mitchell Guss

    The University of Sydney, Sydney, New South Wales, Australia

    Structural biology, metalloproteins

  • Ian B. Holland

    Université Paris-Sud (Paris XI), Orsay, France

    Microbiology, ABC transporters, bacterial protein translocation, microbial communities, signal transduction

  • Barry Honig

    Columbia University, New York, New York, USA

    Computational and theoretical methods to study the structure and function of proteins, nucleic acids and membranes, software tools

  • Gerhard Hummer

    Max Planck Institut (MPI) für Biophysik, Frankfurt am Main, Germany

    Theory and molecular simulation, protein dynamics

  • James H. Hurley

    University of California at Berkeley, Berkeley, California, USA

    Autophagy, mechanisms of coated vesicle formation, structural membrane biology

  • Urs Jenal

    Universität Basel, Basel, Switzerland

    Molecular basis of chronic bacterial signaling and infections in humans, cGMP

  • John E. Johnson

    The Scripps Research Institute, La Jolla, California, USA

    Virus structure and assembly, cryo-EM

  • Charalampos G. Kalodimos

    St. Jude Children's Research Hospital, Memphis, Tennessee, USA

    Molecular chaperones, protein kinases, protein allostery, type III Secretion in bacteria

  • Achillefs Kapanidis

    University of Oxford, Oxford, UK

    Transcription, DNA repair, protein-DNA interactions, single-molecule fluorescence spectroscopy

  • Amy Keating

    Massachusetts Institute of Technology, Cambridge, Massachusetts, USA

    Protein-protein interactions, protein engineering and design, computational structural biology

  • Sepideh Khorasanizadeh

    Sanford-Burnham Medical Research Institute, Orlando, Florida, USA

    Epigenetic mechanisms, transcriptional regulation, therapeutics discovery with small molecules

  • Shohei Koide

    NYU Langone Medical Center, New York, New York, USA

    Protein design and engineering, drug discovery, protein-protein interactions, cellular signaling, structural biology, synthetic biology

  • Steve Kowalczykowski

    University of California, Davis, Davis, California, USA

    Genetic recombination, DNA helicases, protein-nucleic acid interactions

  • Richard Kriwacki

    St. Jude Children's Research Hospital, Memphis, Tennessee, USA

    Cell division and apoptosis, Intrinsically disordered proteins, signal transduction

  • Karolin Luger

    Colorado State University, Fort Collins, Colorado, USA

    Chromatin structure and dynamics, molecular biophysics, proteins and enzymology, structural biology

  • Anthony Maxwell

    John Innes Centre, Norwich, UK

    Structure and function of DNA topoisomerases, antibiotic and herbicide development

  • Daniel L. Minor

    University of California San Francisco, San Francisco, California, USA

    Structure, chemistry, mechanisms and function of ion channels

  • Eva Nogales

    University of California at Berkeley, Berkeley, California, USA

    Cryo-EM visualization of macromolecular complexes, microtubule dynamics and regulation, eukaryotic transcriptional machinery, microtubule-kinetochore interactions, gene silencing

  • Anna Panchenko

    National Center for Biotechnology Information (NCBI), Bethesda, Maryland, USA

    Protein-protein and protein-DNA interactions, cancer driver mutations, epigenetics and nucleosome dynamics, statistical and molecular modeling, molecular dynamics simulations, machine learning

  • Bert Poolman

    Rijksuniversiteit Groningen, Haren, Netherlands

    Synthetic biology, enzymology, membrane biology, transport, signal transduction

  • Anna M. Pyle

    Yale University, New Haven, Connecticut, USA

    Structure, folding and function of long noncoding RNAs, molecular mechanism of RNA helicase proteins and RNA-triggered mechanical devices

  • Georg E. Schulz

    Albert-Ludwigs-Universität Freiburg, Freiburg, Germany

    Membrane protein x-ray crystallography; structure, function and mechanism of enzymes and other proteins; protein engineering

  • James R. Sellers

    National Heart, Lung and Blood Institute (NHLBI), Bethesda, Maryland, USA

    Structure, function, and regulation of myosins; single molecule microscopy

  • Louise Serpell

    University of Sussex, Brighton, UK

    Structure and function of amyloidogenic proteins; neurodegenerative diseases

  • Konstantin Severinov

    Rutgers University, Piscataway, New Jersey, USA

    Transcription initiation and regulation in bacteria, RNA polymerases, bacteriophage development, temporal regulation of gene expression

  • Feng Shao

    National Institute of Biological Sciences, Beijing (NIBS), Beijing, China

    Inflammasome, innate immunity and cell death

  • Yigong Shi

    Tsinghua University, Beijing, China

    apoptosis structural biology.Structural mechanisms of macromolecular machineries, apoptotic pathways, proteasome

  • Ichio Shimada

    University of Tokyo, Tokyo, Japan

    Structural biology of membrane receptors and ion channels, NMR

  • Sachev Sidhu

    University of Toronto, Toronto, Ontario, Canada

    Antibody engineering, protein engineering, phage display technology, protein-protein interactions

  • Titia Sixma

    Nederlands Kanker Instituut (NKI), Amsterdam, Netherlands

    Structural biology of DNA repair, ubiquitin and SUMO modification, chromatin remodeling

  • Arne Skerra

    Technische Universität München, Freising-Weihenstephan, Germany

    Protein engineering and design, biological chemistry

  • Thomas Smith

    The University of Texas Medical Branch at Galveston, Galveston, Texas, USA

    Structural biology, cryo-EM, X-ray

  • Igor Stagljar

    University of Toronto, Toronto, Ontario, Canada

    Cell signalling, membrane transport, protein-protein interactions, proteomics, systems biology

  • Kevin Struhl

    Harvard Medical School, Boston, Massachusetts, USA

    Transcriptional regulation in eukaryotes

  • Dylan J. Taatjes

    University of Colorado, Boulder, Colorado, USA

    Structure and mechanisms of eukaryotic transcription machinery

  • Daniel S. Tawfik

    Weizmann Institute of Science, Rehovot, Israel

    Structure, mechanism and evolution of enzymes

  • Sarah A. Teichmann

    EMBL-European Bioinformatics Institute & Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK

    Transcriptional regulatory networks, gene expression regulation and protein complex assembly

  • Ronald Wetzel

    University of Pittsburgh, Pittsburgh, Pennsylvania, USA

    Amyloids, protein aggregation, neurodegenerative diseases

  • Sarah A. Woodson

    Johns Hopkins University, Baltimore, Maryland, USA

    RNA folding, ribosome assembly, RNA-chaperone interactions

  • Nieng Yan

    Tsinghua University, Beijing, China

    Membrane transporters, mechanisms of substrate recognition and transport

  • Mingjie Zhang

    Hong Kong University of Science and Technology, Kowloon, Hong Kong

    Structural biology of neuronal signaling complex organization and regulation; protein complexes governing cell polarity; screening and development of small molecules with therapeutic potentials

Guest Editors

  • Mazhar Adli

    University of Virginia School of Medicine, Charlottesville, Virginia, USA

  • Emil Alexov

    Dept. of Physics and Astronomy, Clemson University, Clemson, South Carolina, USA

  • Michael Betenbaugh

    Dept. of Chemical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

  • Srinivasan Chandrasegaran

    Dept. of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

  • Ye-Guang Chen

    Dept. of Biological Sciences and Biotechnology, Tsinghua University, Beijing, China

  • Edward T. Chouchani

    Harvard Medical School, Boston, Massachusetts, USA

  • Ünal Coskun

    DZD-Paul Langerhans Institute, Dresden University of Technology, Dresden, Germany

  • Sarah Coulthurst

    Division of Molecular Microbiology of Life Sciences, University of Dundee, Dundee, Scotland, UK

  • Michelle Debatisse

    Institut Curie, Paris, France

  • David Draper

    Dept. of Chemistry, Johns Hopkins University, Baltimore, Maryland, USA

  • Karl Duderstadt

    Max Planck Institut (MPI) für Biochemie, Martinsried, Germany

  • Stuart J Edelstein

    Dept. of Biochemistry, Université de Genève, Genève 4, Switzerland

  • Elena Ezhkova

    Mount Sinai School of Medicine, New York, USA

  • Rick Fishel

    College of Medicine, The Ohio State University, Columbus, Ohio, USA

  • Peter Fraser

    Nuclear Dynamics Programme, Babraham Institute, Cambridge, England, UK

  • Michael Gale (Jr.)

    Dept. of Immunology, University of Washington School of Medicine, Seattle, Washington, USA

  • Rachelle Gaudet

    Howard Hughes Medical Institute (HHMI), Cambridge, Massachusetts, USA

  • Dirk Görlich

    Dept. of Cellular Logistics, Max Planck Institut (MPI) für Biophysikalische Chemie, Göttingen, Germany

  • Gerald W. Hart

    Dept. of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

  • Stephen High

    Fac. of Life Sciences, University of Manchester, Manchester, England, UK

  • Françoise Jacob-Dubuisson

    Institut Pasteur de Lille, Center for Infection and Immunity, CNRS, INSERM, Lille, France

  • Jodie Jenkinson

    University of Toronto, Toronto, Ontario, Canada

  • Katrin Karbstein

    The Scripps Research Institute, La Jolla, California, USA

  • Jonathan Karn

    Dept. Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, Ohio, USA

  • Sharon Krag

    Dept. of Biochemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

  • Mark Liesa-Roig

    School of Medicine, Boston University, Boston, Massachusetts, USA

  • David Liu

    Dept. of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, USA

  • Timothy Lu

    Massachusetts Institute of Technology, Dept. of Biological Engineering, Synthetic Biology Center, Cambridge, Massachusetts, USA

  • Prashant Mali

    University of California at San Diego (UCSD), San Diego, California, USA

  • Eric Martens

    Dept. of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA

  • Andreas Martin

    University of California at Berkeley, Berkeley, California, USA

  • Gael McGill

    Harvard Medical School, Boston, Massachusetts, USA

  • Dejana Mokranjac

    Dept. of Physiological Chemistry, University of Munich, Munich, Germany

  • Walter Neupert

    Max Planck Institut (MPI) für Biochemie, Martinsried, Germany

  • Sean O'Donaghue

    Australia's Commonwealth Scientific and Industrial Research Organization (CSIRO), Sydney, New South Wales, Australia

  • Lori Passmore

    Lab. of Molecular Biology (LMB), Medical Research Council (MRC), Cambridge, UK

  • Ardem Patapoutian

    Dept. of Cell Biology, The Scripps Research Institute, La Jolla, California, USA

  • Stanley Qi

    Stanford University, Stanford, California, USA

  • David Relman

    154T, Veterans Administration Palo Alto Health Care System, Palo Alto, California, USA

  • Benoit Roux

    Inst. of Molecular Pediatric Sciences, Gordon Ctr. for Integrative Science, University of Chicago, Chicago, Illinois, USA

  • Julio Sampaio

    Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Dresden, Germany

  • Karin Sauer

    Dept. of Biological Sciences, Binghamton University, Binghamton, New York, USA

  • Tamar Schlick

    Howard Hughes Medical Institute (HHMI), New York University, New York, New York, USA

  • Kai Simons

    Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Dresden, Germany

  • Justin Sonnenburg

    Dept. of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA

  • Evi Soutoglou

    BP 10142, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France

  • Christian Spahn

    Charité - Universitätsmedizin Berlin, Berlin, Germany

  • Nicola Stanley-Wall

    Division of Molecular Microbiology of Life Sciences, University of Dundee, Dundee, Scotland, UK

  • Aleksandra Trifunovic

    CECAD Research Center, Universität zu Köln, Cologne, Germany

  • Antoine van Oijen

    University of Wollongong, Wollongong, New South Wales, Australia

  • Jonathan Weissman

    University of California at San Francisco, Howard Hughes Medical Institute (HHMI), San Francisco, California, USA

  • Daniel Wilson

    Dept. of Chemistry, Universität Hamburg, Hamburg, Germany

  • Jie Xiao

    John Hopkins Medical Institute, Baltimore, Maryland, USA

  • Marat Yusupov

    Université de Strasbourg, Strasbourg, France