World Rabies Day 2017, 28th of September

Rabies: eliminating the epidemic

Special article collection marks World Rabies Day

Rabies contracted through a dog bite kills someone every nine minutes. In 2017, World Rabies Day (28 September) highlights a campaign to eliminate this global disease by 2030, tackles the problem from two perspectives: vaccinating dogs and protecting people. To mark World Rabies Day, we have collated a special collection of the latest research published in Elsevier journals – free to access until the 28th of December 2017.

Rabies is a virus that affects the nervous system of warm-blooded animals. In 2015, 17,400 people around the world died of rabies, with 99 percent of the infections due to dog bites. The virus is transmitted through the saliva of a rabid animal – not only dogs, but also raccoons, skunks, foxes, bats and pet cats. Following the bite, the virus travels through the nerve tissue to the brain at a rate of one centimetre a day. The virus is fatal unless intercepted with treatment before it enters the nervous system.

Rabies: Zero by 30 is a campaign run by The Global Alliance for Rabies Control (GARC), the World Health Organisation (WHO), the World Organisation for Animal Health (OIE) and the Food and Agriculture Organization of the United Nations (FAO) to eliminate human deaths from canine rabies by 2030.

Research being done around the world supports campaigns like this by improving our knowledge about the disease, uncovering the most effective ways to stop its spread and developing better treatments.

This special article collection features some of the latest rabies research published in Elsevier journals. You can find out why oral vaccination may not be the most effective way to control rabies in wildlife, hear from the experts how rabies can be stopped at country borders and more, by reading the collection – free until the 28th of December 2017.

Selected articles

Preventive Veterinary Medicine

Risk assessment of the entry of canine-rabies into Papua New Guinea via sea and land routes
Victoria J.Brookes, Andy Keponge-Yombo, David Thomson, Michael P.Ward

Characterization of the epidemiology of bat-borne rabies in Chile between 2003 and 2013
Raul Alegria-Moran, Daniela Miranda, Matt Barnard, Alonso Parra, Lisette Lapierre

Domestic dog roaming patterns in remote northern Australian indigenous communities and implications for disease modelling
Emily G.Hudson, Victoria J.Brookes, Salome Dürr, Michael P.Ward

Journal of Clinical Virology

Retrospective diagnosis of two rabies cases in humans by high throughput sequencing
V.G.Dedkov, A.N.Lukashev, A.A.Deviatkin, K.V.Kuleshova, M.V.Safonova, E.M.Poleshchuk , J.F.Drexler, G.A.Shipulin

International Journal of Infectious Diseases

Knowledge and practices regarding rabies in urban and rural communities in Thailand and Cambodia
S.Thongyuan, T.Pinyopummintr, P.Sithisarn, C.Sinthusing, K.Phetudomsinsuk, A.Sangmalee, M.Sukmak, W.Phimpraphai, A.Suprasert

Monoclonal antibody-mediated clearance of rabies virus from the central nervous system: Implications for future approaches to rabies therapy Benedictis, A.Minola, E. RotaNodari, R.Aiello, A.Lanzavecchia, H.Bourhy, D.Corti

Journal of Hospital Infection

Caring for a patient with rabies: implications of the Milwaukee protocol for infection control and public health measures
T.Lampejo, M.Bruce, A.Teall, M.Dall'Antonia, E.Crawley-Boevey, P.Grant, S.Polhill, D.Pillay, D.Brown, M.Brown, E.Nastouli

Journal of Infection

Rabies transmission following organ transplantation in China
ChengGong, Xiaomei Li, Ming Luo, Zhen Zhang, Qinghai Wang, Qing Wang, Lu Zhang, Fang Huang, Tiegang Zhang, Tao Zhou, Fan Yang, Qing Tang, Fan Jiang, Li Lu, Jiang Wu

The potential lethal consequences of rabies vaccine avoidance and dog smuggling in Europe
Elisabeth Botelho-Nevers, Amandine Gagneux-Brunon, Aymeric Cantais, Fathia Daoud, Pascale Fouilloux, Anne Fresard, Celine Cazorla, Matthieu Witz, Gwenael Monnier, Nathalie Guerson, Nathalie Ragozin, Perrine Parize, Herve Bourhy, Laurent Dacheux, Nathalie Pihier, Alexandra Septfons, Marie Guichard, Frederic Lucht

Travel Medicine and Infectious Disease

Familial cluster of exposure to a confirmed rabid dog in travelers to Algeria
Sylvie Antwi, Philippe Parola, Doudou Sow, Victoria Sornin, Maxime Henrion, Philippe Gautret

Evaluation of rabies immunogenicity and tolerability following a purified chick embryo cell rabies vaccine administered concomitantly with a Japanese encephalitis vaccine
Tomas Jelinek, Jakob P.Cramer, Sebastian Dieckmann, Christoph Hatz, Maria Paulke-Korinek, Martin Alberer, Emil C.Reisinger, Marco Costantini, Dieter Gniel, Dietrich Bosse, Maria Lattanzi

Possible cures for clinical rabies: Are they already on the pharmacy shelf?
Stephen Toovey

Journal of Virological Methods

Susceptibility of neuroblastoma cells to rabies virus may be affected by passage number
CraigPouliott, MichelleDupuis, KimAppler, ScottBrunt, RobertRudd, AprilDavis

Antiviral Research

Genetically modified rabies virus-vectored Ebola virus disease vaccines are safe and induce efficacious immune responses in mice and dogs
Lei Shuai, Xijun Wang, Zhiyuan Wen, Jinying Ge, Jinliang Wang, Dandan Zhao, Zhigao Bu

APRIL:TACI axis is dispensable for the immune response to rabies vaccination
Shannon L.Haley, Evgeni P.Tzvetkov, Andrew G.Lytle, Kishore R.Alugupalli, Joseph R.Plummer, James P.McGettigan

The history of rabies in the Western Hemisphere
Andres Velasco-Villa Ph.D, Matthew R. Mauldina, Mang Shic, Luis E. Escobard, Nadia F. Gallardo-Romeroa, Inger Damona, Victoria A. Olsona, Daniel G. Streickere, Ginny Emerson

Successful strategies implemented towards the elimination of canine rabies in the Western Hemisphere
Andres Velasco-Villa Ph.D, Luis E. Escobarb, Anthony Sanchezc, Mang Shid, Daniel G. Streickere, Nadia F.Gallardo-Romeroa, Fernando Vargas-Pinog, Veronica Gutierrez-Cedillog, Inger Damona, Ginny Emerson


Assessment of biosecurity and control measures to prevent incursion and to limit spread of emerging transboundary animal diseases in Europe: An expert survey
Anaïs Léger, Marco De Nardi, Robin Simons, Amie Adkin, Giuseppe Ru, Agustín Estrada-Peña, Katharina D.C. Stärk

Oral vaccination of wildlife against rabies: Differences among host species in vaccine uptake efficiency
Ad Vos, Conrad M. Freuling, Boris Hundt, Christiane Kaiser, Sabine Nemitz, Andreas Neubert, Tobias Nolden, Jens P. Teifke, Verena te Kamp, Reiner Ulrich, Stefan Finke, Thomas Müller

Rabies vaccine is associated with decreased all-cause mortality in dogs
Darryn L. Knobel, Sintayehu Arega, Bjorn Reininghaus, Gregory J.G. Simpson, Bradford D. Gessner, Henrik Stryhn, Anne Conan

Molecular Immunology

Alum adjuvanted rabies DNA vaccine confers 80% protection against lethal 50 LD50 rabies challenge virus standard strain
Rajni Garg, Manpreet Kaur, Ankur Saxenaa, Rajendra Prasad, Rakesh Bhatnagar

Veterinary Immunology and Immunopathology

Multivariate analysis of the immune response to a vaccine as an alternative to the repetition of animal challenge studies for vaccines with demonstrated efficacy
Ludivine Chapat, Florence Hilaire, Jérome Bouvet, Daniel Pialot, Corinne Philippe-Reversat, Anne-Laure Guiot, Lydie Remolue, Jacques Lechenet, Christine Andreoni, Hervé Poulet, Michael J.Day, Karelle De Luca, Carine Cariou, Lionel Cupillard

Research in Veterinary Science

Whole genome sequence phylogenetic analysis of four Mexican rabies viruses isolated from cattle
I.Bárcenas-Reyes, E.Loza-Rubio, G.J.Cantó-Alarcón, J.Luna-Cozar, A.Enríquez-Vázquez, R.J.Barrón-Rodríguez, F.Milián-Suazo

Diagnostic Microbiology and Infectious Disease

Development and Evaluation of a RT-qPCR Assay for Fast and Sensitive Rabies Diagnosis

V.G. Dedkov, A.A. Deviatkin, E.M. Poleshchuk, M.V. Safonova, E.A. Blinova, M. Yu Shchelkanov, G.N. Sidorovd, E.G. Simonova, G.A. Shipulin