GastroHep news

Volume 2, Issue 2

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Top news

Impact is on the rise

This month is metrics month. Starting with the release of the new CiteScores and followed later by the 2016 Impact Factors. CiteScores provide comprehensive, transparent and current insights into journal impact; areas that existing metrics have lagged behind in. In practice this means that over 22,000 journals have a CiteScore, that the metrics is freely available to all and the underlying data can be reviewed. Also a version of the CiteScore is updated on a monthly basis. CiteScores are a valuable new addition to the basket of journal metrics that is available from Elsevier. For more see:

As for the Impact Factors: Gastroenterology and Journal of Hepatology reached their highest Impact Factor ever (18.4 and 12.5 respectively). Gastrointestinal Endoscopy further firmed up its position in the top 10 of the field, rising to 6.5. Both HPB and Digestive and Liver Disease broke through to an Impact Factor above 3.0 (3.3 and 3.1). Clinics and Research in Hepatology and Gastroenterology saw a 24% increase of the IF (to 2.3), putting it among the 20% highest risers this year.

Congratulations and a big word of thanks to the editors, reviewers and authors who made this possible.

Featured content

Clinics and Research H&G

Induced pluripotent stem cells: An unlimited source of organs for transplantation

Organ production outside the human body could address the shortage of organs for transplantation. However, in vitro organ production is still a faraway perspective, particularly because of the difficulty in establishing an effective vascularization. A new emerging technology proposes to use carrier animals for the development of human organs. In this approach, induced pluripotent stem cells (iPSC) are injected in animal embryos to produce chimeric animals that contain autologous human organs.


Gadolinium accumulation in patients with Crohn's disease

Magnetic resonance enterography has been widely used in the past for the evaluation of fistulizing disease, but its use increased over time, being considered helpful in different moments of disease course. Intravenous injection of Gadolinium-based contrast agents (GBCA) has been demonstrated to be crucial to assess mucosal inflammation, transmural involvement, and extraintestinal disease. Recently, Gadolinium accumulation in human tissues has been increasingly reported, although clinical implications of this eventare still unclear. In the present paper, Edoardo Savarino et al. review the main evidence on the topic, focusing on the potentialimplications for gastroenterological practice.


Splenectomy at the time of liver transplantation

Advances in interventional radiology have improved both the management of portal hypertension through the development of transjugular intrahepatic portosystemic shuntsing (TIPSS) and also splenic artery aneurysm management by coiling. As a consequence there are relatively few indications now to perform a splenectomy at the same time as liver transplantation (LT). There are some patients in whom this procedure is indicated and in the June edition of HPB, Golse and colleagues from Lyon in France, discuss the outcomes of their series of patients.


Lessons from a national audit of acute pancreatitis

The National Confidential Enquiry into Patient Outcome and Death (NCEPOD) is an independent organisation whose remit is to review the quality of medical and surgical care provided in the United Kingdom. They undertook a review into the care provided to patients treated for acute pancreatitis to assess care at an organisational level, clinical level within hospitals and external peer review. Derek O'Reilly et al. present the organizations findings and recommendations for improvement here:

The Lancet GH

Stem cells for Crohn’s disease

Options for patients with treatment-refractory Crohn's disease are limited; haematopoeitic stem-cell transplantation (HSCT) might be an alternative. In the ASTIC trial, patients underwent stem-cell mobilisation and were randomly assigned to immediate autologous HSCT or conventional therapy followed by HSCT after 1 year. The primary results of the study, using a stringent primary outcome at 1 year after randomisation, suggested that HSCT offered no benefit to patients. In The Lancet Gastroenterology & Hepatology, a pooled analysis of all patients who underwent HSCT, irrespective of original assignment, assesses outcomes on more conventional endpoints for Crohn's disease and examines prognostic factors that might predict which patients could benefit from stem-cell transplantation.


Duodenoscope reprocessing surveillance with adenosine triphosphate testing and terminal cultures: a clinical pilot study

Recent reports of infectious outbreaks involving multidrug-resistant organisms linked to duodenoscopes, which occurred despite reprocessing in accordance with the manufacturer’s instructions and professional guidelines, have led to proposals for surveillance culturing, which has inherent limitations. Kavel Visrodia and colleagues assessed the feasibility of real-time adenosine triphosphate testing and manual cleaning and its ability to predict reprocessing adequacy, as determined by terminal duodenoscope cultures.

Special issues


An endoscopic response to the obesity epidemic

The January issue of Techniques in Gastrointestinal Endoscopy discusses current paradigms in the etiology of obesity and endoscopic therapies.  The global prevalence of obesity continues to rise at an alarming rate and 37.7% of US adults are obese. The majority of adults who qualify for weight loss surgery do not get the procedure.  Endoscopic options for obesity management are expanding and may be appropriate for many of those who are not able to undergo surgical interventions. This issue addresses endoscopic options for weight loss, including a review of the data for gastric space occupying devices along with the potential role for new endoscopic remodeling techniques and other small bowel interventions. In addition, this issue addresses the role of endoscopic therapies in the bariatric surgical approach and provides a working paradigm for the treatment of obesity.


H. pylori in the Arab Journal of Gastroenterology

Arab Journal of Gastroenterology is publishing two original articles in the June issue from Turkey on optimizing H.pylori eradication. The global health burden of H.pylori infection and the different antibiotic resistance patterns in various parts of the world is a challenge in gastroenterological practice.  For that reason, AJG is keen on reporting the situation from different countries.  Reports on H. pylori from Egypt, Kuwait, Iran, Iraq, Saudi Arabia, UAE, and Venezuela were previously published. AJG welcomes submissions on this topic which would fill a knowledge gap and help the gastroenterology community understand the changing epidemiologic patterns, virulence factors, antibiotic resistance and cost-effective eradication protocols used in various regions.


Liver failure and liver transplant

What does the future hold in the field of liver transplantation? The incidence of both cirrhosis and HCC is increasing. Non-alcoholic fatty liver disease (NAFLD) has made its steady, but rapid appearance in the field of liver diseases. On the other hand there is progress in achieving reversal of liver fibrosis. And signs that stem cells or organoids can be used to repair the liver or build it “new” liver. These and other exciting topics are all covered in the special issues organized by Herold Metselaar en published in Best Practice & Research: Clinical Gastroenterology.

Journal news


Explaining the journal to a lay audience

Hepatology is a field of tremendous interest to a lay audience. Topics like cures for hepatitis C and fatty liver disease have implications beyond research and the clinic. Many can relate to costs of healthcare and the right life style choices. Articles can be dense and jargon prevents lay readers to grasp their significance. To address that issue, the Journal of Hepatology has introduced lay summaries in which authors explain in simple terms what their article is about. These are collected for each issue to ensure the best accessibility to the widest audience.


VideoGIE celebrates its first anniversary

VideoGIE, the American Society for Gastrointestinal Endoscopy’s new Open Access, online-only journal is celebrating its 1-year anniversary! VideoGIE publishes original, peer-reviewed video case reports and case series of endoscopic procedures used in the study, diagnosis, and treatment of digestive diseases. If you have an interesting or educational video that you would like to share with the endoscopic community, consider submitting to VideoGIE, and don’t forget to check out our Facebook and Twitter pages for the latest news and article links.

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The Lancet Gastroenterology & Hepatology