Fully updated from cover to cover, Zipes and Jalife’s Cardiac Electrophysiology: From Cell to Bedside, 8th Edition, provides the comprehensive, multidisciplinary coverage you need—from new knowledge in basic science to the latest clinical advances in the field. Drs. José Jalife and William Gregory Stevenson lead a team of global experts who provide cutting-edge content and step-by-step instructions for all aspects of cardiac electrophysiology.
Current TOC; final to be done in summer 2019:
Section 1 STRUCTURAL AND MOLECULAR BASES OF ION CHANNEL FUNCTION
1. Voltage-gated sodium channels and electrical excitability of the heart
2. Voltage-gated calcium
3. Voltage-gated potassium channels
4. Structural and molecular bases of cardiac inward rectifier potassium channel function
5. Mammalian calcium pumps in health and disease
6. Structural and molecular bases of sarcoplasmic reticulum ion channel function
7. Organellar ion channels and transporters
8. Molecular organization, gating, and function of connexin-based gap junction channels and hemichannels
Section 2 BIOPHYSICS OF CARDIAC ION CHANNEL FUNCTION
9. Structure-function relations of heterotrimetric complexes of sodium channel a and β subunits
10. Regulation of cardiac calcium channels
11. Inhibition of phosphoinositide 3-kinase and acquired long QT syndrome
12. Structural determinants and biophysical properties of hERG1 channel gating
13. Molecular regulation of cardiac inward rectifier potassium channels by pharmacologic agents
14. Cardiac stretch-activated channels and mechano-electric coupling
15. Biophysical properties of gap junctions
16. Excitation-contraction coupling
Section 3 INTERMOLECULAR INTERACTIONS AND CARDIOMYOCYTE ELECTRICAL FUNCTION
17. Ion channel trafficking in the heart
18. Microdomain interactions of macromolecular complexes and regulation of the sodium channel nav1.5
19. Fibroblast growth factor homologous factors modulate cardiac calcium channels
20. Macromolecular complexes and cardiac potassium channels
21. Reciprocity of cardiac sodium and potassium channels in the control of excitability and arrhythmias
22. The intercalated disc: A molecular network that integrates electrical coupling, intercellular adhesion an
- No. of pages:
- © Elsevier 2021
- 1st December 2021
- Hardcover ISBN:
José Jalife, MD, is Professor of Internal Medicine and Cyrus and Jane Farrehi Professor of Cardiovascular Research; Professor of Molecular and Integrative Physiology; and Director of the Center for Arrhythmia Research at the University of Michigan in Ann Arbor
Cyrus and Jane Farrehi Professor of Cardiovascular Research,Department of Internal Medicine, Professor of Molecular and Integrative Physiology, Co-Director for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan Senior Investigator, Fundacion Centro Nacional De Investigaciones Cardiovascularres (CNIC), Madrid, Spain
Dr Jalife is also actively conducting research at the Centro Nacional de Investigaciones Cardiovasculares, in Madrid, Spain. William Gregory Stevenson, MD, is Professor of Medicine at Vanderbilt University School of Medicine in Nashville, Tennessee. Dr Jalife will assume the role of lead editor on the 8th edition with Douglas Zipes’s retirement
Director, Cardiac Arrhythmia Program, Cardiovascular Division, Brigham and Women's Hospital; Professor of Medicine Harvard Medical School, Boston, MA
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