From Understanding to Investigation

2nd Edition - October 1, 2022

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  • Author: Susan Payne
  • Paperback ISBN: 9780323903851

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Viruses: From Understanding to Investigation, Second Edition presents the definitions and unique characteristics of viruses, including major topics such as virus lifecycle, structure, taxonomy, evolution, history, host-virus interactions and methods to study. In addition, the book assesses the connections between, and among, the aforementioned topics, providing an integrated approach and in-depth understanding of how viruses work. This new edition provides expanded chapters on bioinformatics, mathematical formulas to calculate titers, identification of novel viruses, mRNA vaccines, vaccine successes, mechanisms of virally induced cancers, nucleocytoplasmic viruses (very large DNA viruses), replication of viroids and virusoids, and a major section on SARS CoV-2.

Key Features

  • Employs a comparative strategy to emphasize unique structural and molecular characteristics that inform transmission, disease processes, vaccine strategies and host responses
  • Presents a review of host cell, molecular biology and the immune system
  • Features topical areas of research, including genomics in virus discovery, the virome, and beneficial interactions between viruses and their hosts
  • Includes text boxes throughout with experimental approaches used by virologists
  • Covers learning objectives in each chapter, along with methods and advances, question sets, quizzes and a glossary


Advanced undergraduate, graduate students, and professors in virology, molecular biology and microbiology

Table of Contents

  • 1. Introduction to Animal Viruses
    2. Virus Structure
    3. Virus Interactions with the Cell
    4. Methods to Study Viruses
    5. Virus Transmission and Epidemiology
    6. Immunity and Resistance to Viruses
    7. Viral Vaccines
    8. Antiviral Drugs
    9. Virus Evolution and Genetics
    10. Viral Pathogenesis [revise to include cancers produced by viruses]
    11. Introduction to RNA viruses [add a section on replication of viroids and virusoids]
    12. Family Picornaviridae
    13. Family Caliciviridae
    14. Family Hepeviridae
    15. Family Astroviridae
    16. Family Flaviviridae
    17. Family Togaviridae
    18. Family Coronaviridae [revise to include major section on SARS Co-V 2, Covid-19]
    19. Family Artiriviridae
    20. Family Rhabdoviridae
    21. Families Paramyxoviridae and Pneumoviridae
    22. Family Filoviridae
    23. Family Bornaviridae
    24. Family Orthmyxoviridae
    25. Family Bunyaviridae
    26. Family Arenaviridae
    27. Family Reoviridae
    28. Family Birnaviridae
    29. Introduction to DNA viruses
    30. Family Parvoviridae
    31. Other Small DNA Viruses
    32. Family Polyomaviridae
    33. Family Papillomaviridae
    34. Family Adenoviridae
    35. Family Herpesviridae
    36. Family Poxviridae
    37. Nucleocytoplasmic viruses (Very large DNA Viruses) [new proposed chapter]
    38. Family Retroviridae
    39. Replication and Pathogenesis of Human Immunodeficiency Virus
    40. Family Hepadnaviridae

Product details

  • No. of pages: 396
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: October 1, 2022
  • Imprint: Academic Press
  • Paperback ISBN: 9780323903851

About the Author

Susan Payne

Susan Payne's primary research interest is the molecular aspects of viral replication, pathogenesis, and evolution. The major focus of her laboratory is the retrovirus, equine infectious anemia virus. EIAV studies include evolution of virulence during rapid virus passage, modification of cell signaling pathways mediated by viral glycoproteins, effects of proinflammatory cytokines on virus replication and disease, and detailed mapping of EIAV virulence determinants. She also studies the recently discovered avian bornavirus, etiological agent of proventricular dilatation disease of parrots, in conjunction with colleagues from the Schubot center.

Affiliations and Expertise

Associate Professor, Department of Veterinary Medicine and Biomedical Sciences, Texas A&M University, USA

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