Viruses

From Understanding to Investigation

2nd Edition - September 23, 2022

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Author: Susan Payne
Paperback ISBN: 9780323903851
eBook ISBN: 9780323984768

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Description

Viruses: From Understanding to Investigation, Second Edition presents the definitions and unique characteristics of viruses. The book includes major topics such as virus lifecycle, structure, taxonomy, evolution, history, host-virus interactions, and methods to study. In addition, the book assesses the connections between the aforementioned topics and provides an integrated approach and in-depth understanding of how viruses work. The new edition also provides an expanded methods chapter containing new information on deep sequencing for in virus identification, mathematical formulas to calculate titers and a description of quantitiative PCR for enumerating viruses. The vaccine chapter has been updated to include vaccine efficacy, mRNA vaccines and SARS-CoV-2 vaccine development. The viral pathogenesis chapter has been expanded to include mechanisms of virally induced cancers. Viral taxonomy sections have been updated and chapters revised to accommodate new virus family designations. New chapters include nucleocytoplasmic viruses (very large DNA viruses), replication of viroids and COVID-19/SARS-CoV-2.

Key Features

Employs a comparative strategy to emphasize unique structural and molecular characteristics that inform transmission, disease processes, vaccine strategies, and host responses
Presents a review of host cell, molecular biology, and the immune system
Features topical areas of research, including genomics in virus discovery, the virome, and beneficial interactions between viruses and their hosts
Includes text boxes throughout with experimental approaches used by virologists
Covers learning objectives in each chapter

Readership

Advanced undergraduate, graduate students, and professors in virology, molecular biology and microbiology

1. Introduction to animal viruses
2. Virus structure
3. Virus interactions with the cell
4. Methods to study viruses
5. Virus transmission and epidemiology
6. Immunity and resistance to viruses
7. Viral vaccines
8. Antiviral agents
9. Virus evolution and genetics
10. Viral pathogenesis
11. Introduction to RNA viruses
12. Family Picornaviridae
13. Family Caliciviridae
14. Family Hepeviridae
15. Family Astroviridae
16. Family Flaviviridae
Families Togaviridae and Matonaviridae
18. Family Coronaviridae
19. SARS-CoV-2/COVID-19
20. Family Arteriviridae
21. Family Rhabdoviridae
22. Family Paramyxoviridae
23. Family Pneumoviridae
24. Family Filoviridae
25. Family Bornaviridae
26. Family Orthomyxoviridae
27. Family Hantaviridae
28. Order Bunyavirales: Families Peribunyaviridae, Phenuiviridae, and Nairoviridae
29. Family Arenaviridae
30. Family Reoviridae
31. Family Birnaviridae
32. Hepatitis delta virus
33. Introduction to DNA viruses
34. Family Parvoviridae
35. Other small DNA viruses
36. Family Polyomaviridae
37. Family Papillomaviridae
38. Family Adenoviridae
39. Family Herpesviridae
40. Family Poxviridae
41. Other large DNA viruses
42. Family Retroviridae
43. Replication and pathogenesis of human immunodeficiency virus
44. Family Hepadnaviridae

Product details

No. of pages: 438
Language: English
Published: September 23, 2022
Imprint: Academic Press
Paperback ISBN: 9780323903851
eBook ISBN: 9780323984768

About the Author

Susan Payne

Susan Payne is an associate professor emeritus at Texas A&M University. Her primary research interests were molecular aspects of viral replication, pathogenesis and evolution. For many years her research focused on equine infectious anemia virus (EIAV), an equine retrovirus. She published extensively on genetic and antigenic variation and the molecular basis of EIAV pathogenesis. She also studied avian bornaviruses, negative strand RNA viruses that are the etiological agents of proventricular dilatation disease of parrots. Her long teaching career included courses for undergraduate and graduate students as well as participation in courses for medical and veterinary students. She was a member of the Bornavirus Study Group of the International Committee for Taxonomy of Viruses from 2014-2019.

Affiliations and Expertise

Associate Professor, Department of Veterinary Medicine and Biomedical Sciences, Texas A&M University, USA

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