From Understanding to Investigation

1st Edition - August 10, 2017

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  • Author: Susan Payne
  • eBook ISBN: 9780128031100
  • Paperback ISBN: 9780128031094

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Viruses: From Understanding to Investigation provides students with a map for lifetime learning by presenting the definition and unique characteristics of viruses, including major topics, such as the virus lifecycle, structure, taxonomy, evolution, history, host-virus interactions and methods to study viruses. In addition, the book assesses the connections between, and among, the aforementioned topics, providing an integrated approach and in-depth understanding of how viruses work.

Key Features

  • Employs a comparative strategy to emphasize unique structural and molecular characteristics that inform transmission, disease processes, vaccine strategies and host responses
  • Presents a review of host cell and molecular biology and the immune system
  • Features topical areas of research, including genomics in virus discovery, the virome, and beneficial interactions between viruses and their hosts
  • Includes text boxes throughout with experimental approaches used by virologists
  • Covers learning objectives for each chapter, methods and advances, question sets, quizzes and a glossary


Students and professors in virology, molecular biology and microbiology; researchers entering the virology, infectious disease, and immunology research

Table of Contents

  • 1. A brief introduction to virology
    2. The virus replication cycle
    3. Virus structure
    4. How we study viruses
    5. Molecular and cell biology of the eukaryotic cell
    6. Virus interactions with the host
    7. Antiviral responses
    8. An introduction to RNA viruses
    9. Picornaviridae
    10. Caliciviridae
    11. Flaviviridae and Togaviridae
    12. Order Nidovirales
    13. Order Mononegavirales
    14. Bunyaviridae
    15. Arenaviridae
    16. Orthomyxoviridae
    17. Reoviridae
    18. Introduction to DNA viruses
    19. Poxviridae
    20. Circoviridae
    21. Parvoviridae
    22. Papillomaviridae
    23. Polyomaviridae
    24. Adenoviridae
    25. Herpesviridae
    26. Viruses that use reverse transcription
    27. The human hepatitis viruses
    28. Evolution and genetics of viruses
    29. Immune responses to viruses
    30. Vaccines: Principles and approaches
    31. Antiviral drugs and treatment strategies
    32. Viral vectors and gene thereapy

    Appendix 1. The viruses we know -- lists, tables of taxonomy
    Appendix 2. Biochemical methods to study viruses -- analyzing proteins and nucleic acids
    Appendix 3. Tables describing morbidity and mortality (WHO)
    Appendix 4. Glossary

Product details

  • No. of pages: 352
  • Language: English
  • Copyright: © Academic Press 2017
  • Published: August 10, 2017
  • Imprint: Academic Press
  • eBook ISBN: 9780128031100
  • Paperback ISBN: 9780128031094

About the Author

Susan Payne

Susan Payne is an associate professor emeritus at Texas A&M University. Her primary research interests were molecular aspects of viral replication, pathogenesis and evolution. For many years her research focused on equine infectious anemia virus (EIAV), an equine retrovirus. She published extensively on genetic and antigenic variation and the molecular basis of EIAV pathogenesis. She also studied avian bornaviruses, negative strand RNA viruses that are the etiological agents of proventricular dilatation disease of parrots. Her long teaching career included courses for undergraduate and graduate students as well as participation in courses for medical and veterinary students. She was a member of the Bornavirus Study Group of the International Committee for Taxonomy of Viruses from 2014-2019.

Affiliations and Expertise

Associate Professor, Department of Veterinary Medicine and Biomedical Sciences, Texas A&M University, USA

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  • Christopher R. Mon May 14 2018

    Viruses : From understanding to Investigation. Susan Payne. Publ. Academic Press.

    As a Master’s degree Programme Leader I like to keep abreast with the latest textbooks in my area and I am aware of four, fairly similar, although very good, virology textbooks that have been published over the last couple of years. Viruses: From Understanding to Investigation is now the fifth. I must admit, I’m still a little perplexed by the title. It isn’t so different from the other recently-published textbooks, and is probably most similar to Molecular Virology of Human Pathogenic Viruses by Ryu, also published by Academic Press. In my opinion the most significant difference between these books is that Viruses: From Understanding to Investigation is almost twice the price (£55 vs £99 for the paperback versions). One might be prepared to pay extra for a more up-to-date book but these books are only a year apart so I do not understand why there is so much difference in price. Having said that, Viruses: From Understanding to Investigation is a very good virology textbook, covering viral structures, interactions with the host cell, techniques used to study viruses, transmission, immunity, evolution and pathogenesis, before focusing in on details of each family of RNA and DNA viruses. The illustrations are very clear and engaging, making it a very attractive and informative textbook. I’m sure that enthusiastic undergraduates and postgraduate students will find this book very helpful in their understanding and investigation of viruses, but if they do purchase a textbook, I strongly suspect they will opt for a cheaper one.