Viruses and Human Disease

Viruses and Human Disease

1st Edition - January 31, 2002

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  • Authors: Ellen Strauss, James Strauss
  • eBook ISBN: 9780080521688

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This is the first text to examine the connection between virology and human disease. It is also the first book to integrate basic virology with pathophysiological conditions. By contrast, most virology textbooks focus on the molecular biology involved without adequate reference to physiology. Viruses and Human Disease is four-color throughout and contains clearly labeled figures and tables.

Key Features

Key Features
*Provides a concise overview of animal viruses, emphasizing those causing diseases in humans;
* Integrates discussion of molecular biology, epidemiology, and the history of human viruses;
* Presents treatment of prions, gene therapy, and vaccine development;
* Illustrated in color by an expert virologist;
* Includes world maps depicting the current distribution of existing and newly emerging viruses


Advanced undergraduate and graduate students in virology, molecular biology, and microbiology.

Table of Contents

  • Contents


    1. Overview of Viruses and Virus Infection


    Classification of Viruses

    An Overview of the Replication Cycle of Viruses

    Effects of Virus Infection on the Host Cell

    Epidemiology: The Spread of Viruses from Person to Person

    Further Reading

    2. The Structure of Viruses


    Helical Symmetry

    Icosahedral Symmetry

    Nonenveloped Viruses with More Complicated Structural Features

    Enveloped Viruses

    Assembly of Virions

    Stability of Virions

    Further Reading

    3. Plus-Strand RNA and Double-Strand RNA Viruses


    Family Picornaviridae

    Family Caliciviridae

    Family Astroviridae

    Family Togaviridae

    Family Flaviviridae

    Family Coronaviridae

    Family Arteriviridae

    Family Papillomaviridae

    Family Parvoviridae

    TT Virus: A Newly Described Human Virus

    Further Reading

    The Plus-Strand RNA Viruses of Plants

    Origin and Evolution of Plus-Strand RNA Viruses

    Viruses That Contain Double-Stranded RNA: Family Reoviridae

    Further Reading

    4. Minus-Strand RNA Viruses


    Overview of the Minus-Strand RNA Viruses

    Family Rhabdoviridae

    Family Paramyxoviridae

    Family Filoviridae

    Family Bornaviridae

    Family Orthomyxoviridae

    Family Bunyaviridae

    Family Arenaviridae

    Evolution of Minus-Strand RNA Viruses

    Further Reading

    5. Viruses Whose Life Cycle Uses Reverse Transcriptase


    Family Retroviridae

    Family Hepadnaviridae

    Further Reading

    6. DNA-Containing Viruses


    Family Poxviridae

    Family Herpesviridae

    Family Adenoviridae

    Family Polyomaviridae

    7. Subviral Agents


    Defective Interfering Viruses

    Satellites and Satellite Viruses

    Viroids and Virusoids

    Hepatitis δ

    Prions and Prion Diseases

    Further Reading

    8. Host Defenses against Viral Infection and Viral Counterdefenses


    Adaptive Immune System

    Innate Immune System

    Viral Counterdefenses

    Interactions of Viruses with Their Hosts

    Further Reading

    9. Gene Therapy


    Virus Vector Systems

    Use of Viruses as Expression Vectors

    Further Reading

    Appendix A

    References for Figures

    Appendix B

    References for Tables


Product details

  • No. of pages: 383
  • Language: English
  • Copyright: © Academic Press 2002
  • Published: January 31, 2002
  • Imprint: Academic Press
  • eBook ISBN: 9780080521688

About the Authors

Ellen Strauss

Affiliations and Expertise

California Institute of Technology, U.S.A.

James Strauss

Affiliations and Expertise

California Institute of Technology, U.S.A.

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