Description

Gene therapy offers considerable potential for the treatment of various incurable diseases of the nervous system. This volume describes a number of different viral vectors developed for achieving high efficiency gene delivery to the brain. Vectors described include those based on adenovirus, adeno-associated virus, Herpes Simplex Virus, lentivirus, and other retroviruses. It also discusses the potential application of such viruses in treating brain tumors, Parkinson's disease, and other diseases of the nervous system.

Key Features

* Provides up-to-date account of gene therapy approaches for incurable neurological disorders * Describes a range of gene delivery methods based on different viruses

Readership

Neuroscientists, neurologists, virologists, and geneticists.

Table of Contents

Section A: Virus Vectors for Use in the Nervous System Section B: Gene Therapy with Virus Vectors for Specific Disease of the Nervous System

Details

No. of pages:
329
Language:
English
Copyright:
© 2003
Published:
Imprint:
Academic Press
eBook ISBN:
9780080918914
Print ISBN:
9780123668561

About the editor

David Latchman

Affiliations and Expertise

Master of Birkbeck, University of London, Professor of Genetics, Birkbeck and University College London, UK

Reviews

Gene therapy offers considerable potential for the treatment of various incurable diseases of the nervous system. This volume describes a number of different viral vectors developed for achieving high efficiency gene delivery to the brain. Vectors described include those based on adenovirus, adeno-associated virus, Herpes Simplex Virus, lentivirus, and other retroviruses. It also discusses the potential application of such viruses in treating brain tumors, Parkinson's disease, and other diseases of the nervous system.