Viral Immunology and Immunopathology

Viral Immunology and Immunopathology

1st Edition - January 1, 1975

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  • Editor: Abner Louis Notkins
  • eBook ISBN: 9781483218977

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Viral Immunology and Immunopathalogy covers topics concerning the role of cellular and humoral immunity in viral infections, factors responsible for the persistence and recurrence of viral infections in the presence of immunity, mechanisms of viral immunopathology, and concepts in the development of vaccines. The book describes the history of viral immunology; the synthesis and properties of viral antigens; and the humoral immune response to viruses. The text also discusses the mechanisms of viral neutralization; cellular immunity; the role of inflammatory cells and effector molecules in combating viral infections; and the genetic control of resistance. The book concludes with chapters on herd immunity; viral immunopathology; and viral immunology and immunopathology. Immunologists, pathologists, virologists, and microbiologists will find the book useful.

Table of Contents

  • Contents

    Authors and Participants


    1. History of Viral Immunology

    2. Viral Replication

    3. Viral Antigens

    4. Humoral Immune Response to Viral Infections

    5. Mechanisms of Viral Neutralization

    6. Destruction of Virus-Infected Cells by Antibody and Complement

    7. Cell-Mediated Immunity in Viral Infections

    8. The Role of the Inflammatory Response in Viral Infections

    9. Interferon as a Mediator of Cellular Immunity in Viral Infections

    10. Genetic Control of Resistance to Viral Infection in Mice

    11. Persistence of Viral Infection in the Presence of Immunity

    12. Radioimmunoassays for Detection of Viral Antigens and Antiviral Antibody

    13. Immune Response to Hepatitis Viruses

    14. Immune Response to Leukemia Viruses in Mice

    15. Immune Responses to Epstein-Barr Virus

    16. Herd Immunity—Changing Concepts

    17. Current Approaches to Viral Immunoprophylaxis

    18. Subunit Viral Vaccines

    19. Adverse Effects of Viral Vaccines

    20. Immune-Complex Disease Associated with Viral Infections

    21. Virus-Induced Cell-Mediated Immunopathological Disease

    22. The Effect of Viral Infections on the Function of the Immune System

    23. Autoimmunity in Viral Infections

    24. The Future in Viral Immunology and Immunopathology

    Appendix. Summary of Workshop

    Subject Index

Product details

  • No. of pages: 496
  • Language: English
  • Copyright: © Academic Press 1975
  • Published: January 1, 1975
  • Imprint: Academic Press
  • eBook ISBN: 9781483218977

About the Editor

Abner Louis Notkins

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