Viral Gastroenteritis

Viral Gastroenteritis

Molecular Epidemiology and Pathogenesis

1st Edition - June 27, 2016

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  • Authors: Lennart Svensson, Ulrich Desselberger, Mary Estes, Harry Greenberg
  • eBook ISBN: 9780128026595
  • Paperback ISBN: 9780128022412

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Viral Gastroenteritis: Molecular Epidemiology and Pathogenesis provides a comprehensive review of research on viruses causing acute gastroenteritis in infants and young children, including coverage of rotaviruses, human caliciviruses, astroviruses, enteric adenoviruses, and viruses causing gastroenteritis more rarely. Includes general chapters on gastrointestinal physiology and pathophysiology, gastrointestinal immune mechanisms, immunodeficiencies and host genetics influencing susceptibility to viral gastroenteritis, and therapeutic and preventative approaches. The book also includes special sections on virus particle structures, replication cycles, pathogenesis, immunology, epidemiology, and preventative measures. This book covers both basic science and translational applications and is an appropriate resource for virologists, molecular biologists, epidemiologists, gastroenterologists, vaccinologists, and those with an interest in public health.

Key Features

  • Features new approaches in diagnosis and characterization of viral gastroenteritis pathogens
  • Includes coverage of therapeutic and preventative methods
  • Covers recent advances in characterizing the molecular biology and immune responses of rotaviruses and noroviruses
  • Covers both basic science and translational applications and is an appropriate resource for virologists, molecular biologists, epidemiologists, gastroenterologists, vaccinologists, and those with an interest in public health


Virologists, gastroenterologists, molecular biologists, immunologists, pathophysiologists, epidemiologists, vaccinologists, pediatricians and physicians (infectious diseases), and public health physicians

Table of Contents

  • 1. Gastrointestinal physiology and pathophysiology
    2. Gastrointestinal immunity
    3. Host genetics and susceptibility to gastrointestinal infections
    4. Immunodeficiencies, in particular IgA deficiency
    5. Metagenomics of viruses infecting the gut
    6. Gut microbiota and disease
    7. Therapy of gastroenteritis
    8. Rotavirus
    9. Structure function
    10. Replication (4-5 chapters)
    11. Pathogenesis (2 chapters)
    12. Immunology (2 chapters)
    13. Molecular epidemiology and evolution
    14. Vaccine and therapeutic developments and implementation (2 chapters)
           - Human caliciviruses
     - Structure function
     - Replication (2 chapters)
     - Animal models
     - Epidemiology and evolution (2 chapters)
     - Vaccine development
           - Astroviruses
     - Structure function
     - Replication (2 chapters)
     - Epidemiology
           - Other viruses causing gastroenteritis
     - Aichi virus
     - Enteroviruses
     - Picobirnavirus

Product details

  • No. of pages: 588
  • Language: English
  • Copyright: © Academic Press 2016
  • Published: June 27, 2016
  • Imprint: Academic Press
  • eBook ISBN: 9780128026595
  • Paperback ISBN: 9780128022412

About the Authors

Lennart Svensson

Lennart Svensson is the Professor of Molecular Biology at Linköping University. He is presently researching virus disease mechanisms and the human genetics of susceptibility, with particular focus on the rotavirus and the norovirus.During his research, he and his team have contributed many important observations to the field regarding the processes of and reactions to these viruses in the human body.

Affiliations and Expertise

Linköping Universitet, Sweden

Ulrich Desselberger

Ulrich Desselberger is a Professor in the Department of Medicine, of which he is the director, at the University of Cambridge whilst also actively consulting. He specialises in the molecular biology of rotaviruses.

Affiliations and Expertise

Department of Medicine, University of Cambridge, UK

Mary Estes

Mary K Estes is the Professor of Virology and Microbiology at Baylor College of Medicine. Mary specialises in gastrointestinal viruses. Her academic career has seen her win many accolades including the Presidency of the American Society for Virology, and more recently the AGA Distinguished Achievement Award.

Affiliations and Expertise

Molecular Virology and Microbiology, Baylor College of Medicine

Harry Greenberg

Harry B Greenberg is a Professor of the department of Microbiology and Immunology at the Stanford School of Medicine. On top of this position he also holds the Jospeh D Grant Professorship, is Director of Spectrum and the Senior Associate Dean for Research. Amongst his honors and awards, he has served as president of the American Society of Virology.

Affiliations and Expertise

Professor of Microbiology and Immunlogy, Stanford School of Medicine

Ratings and Reviews

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  • Hiroko M. Tue Mar 13 2018

    Resource for viruses causing diarrhea

    This book is recommended especially to those interested in public health issues (e.g., outbreak situation including food poisoning caused by viruses) and/or nosocomial infection.