Vibrational Spectroscopy Applications in Biomedical, Pharmaceutical and Food Sciences

Vibrational Spectroscopy Applications in Biomedical, Pharmaceutical and Food Sciences

1st Edition - July 24, 2020

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  • Authors: Andrei Bunaciu, Hassan Aboul Enein, Vu Dang Hoang
  • eBook ISBN: 9780128188286
  • Paperback ISBN: 9780128188279

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Vibrational Spectroscopy Applications in Biomedical, Pharmaceutical and Food Sciences synthesizes the latest research on the applications of vibrational spectroscopy in biomedical, pharmaceutical and food analysis. Suitable for graduate-level students as well as experienced researchers in academia and industry, this book is organized into five distinct sections. The first deals with the fundamentals of vibrational spectroscopy, with the second presenting the most important sampling methodology used for infrared and Raman spectroscopy in various fields of interest. Since spectroscopy is the study of the interaction of electromagnetic radiation with matter, this section deals with the characteristics, properties and absorption of electromagnetic radiation. Final sections describe the analytical studies performed all over the world in biomedical, pharmaceutical and in the food sciences.

Key Features

  • Presents a critical discussion of many of the applications of vibrational spectroscopy
  • Covers details of the analytical methodologies used in pharmaceutical and biomedical applications
  • Discusses the latest developments in pharmaceutical and biomedical analysis of both small and large molecules


Researchers and scientists in analytical chemistry, quality control and assurance, and clinical chemistry involved the application of vibrational spectroscopy in pharmaceutical or biomedical analysis, clinical research and development, bioinorganic chemistry, forensic science, and food science. Graduate students, and faculty members, and scholars studying vibrational spectroscopy in physics and chemistry

Table of Contents

  • 1. Introduction

    2. Molecular vibration
    3. Infrared absorption
    4. Raman scattering
    5. Surface-enhanced effect

    6. Sampling in Infrared spectroscopy
    7. Sampling in Raman Spectroscopy

    8. Body fluids analysis
    9. Tissues analysis
    10. Biomedical analysis
    11. Clinical diagnosis

    12. Drugs
    13. Polymorphic substances analysis

    14. Fruit and vegetable analysis
    15. Solid and semisolid dairy product analysis
    16. Alcohol beverages analysis
    17. Conclusions

Product details

  • No. of pages: 268
  • Language: English
  • Copyright: © Elsevier 2020
  • Published: July 24, 2020
  • Imprint: Elsevier
  • eBook ISBN: 9780128188286
  • Paperback ISBN: 9780128188279

About the Authors

Andrei Bunaciu

Andrei A. Bunaciu, received his Ph.D. from Politehnica University of Bucharest, Faculty of Chemistry, Department of Analytical Chemistry in the field of ion-selective membrane electrodes applied in pharmaceutical analysis in 1990. After several years as Senior Researcher in the Institute of Chemical and Pharmaceutical Research and Romanian Intelligence Service, he became a Senior Researcher in the Vibrational Spectroscopy Department at SCIENT - Research Center for Instrumental Analysis, Bucharest. Now he is the owner of AAB_IR research company. His research interests concern molecular recognition of pharmaceutical and biological compounds using infrared and Raman spectroscopy techniques. He is the author/co-author of about 80 publications on various aspects of sensors, vibrational spectroscopy, and other instrumental techniques in medical and pharmaceutical analysis.

Affiliations and Expertise

AAB-IR Research Laboratory, Bucharest, Romania

Hassan Aboul Enein

Hassan Y. Aboul Enein is a Professor Emeritus at the National Research Center in Cairo, Egypt. He was head of the Pharmaceutical Analysis Laboratory at King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. He is an author of over 1100 refereed articles, 48 book chapters and 365 conference presentations. He also authored and edited 8 books. He is an Editorial Board Member of 22 journals, including Analytica Chimica Acta, Chirality, Biomedical Chromatography, Critical Reviews in Analytical Chemistry, Journal of Separation Science, Chromatographia, and Chirality. He is a member of the World Health Organization (WHO) advisory panel in International Pharmacopoeia and Pharmaceutical Preparations and a Fellow of the Royal Society of Chemistry (UK). He received his Ph.D. in 1971 in pharmaceutical and medicinal chemistry from the University of Mississippi, USA. He has received several awards, including the Scopus award for the most cited scientist in the Middle East in 2009.

Affiliations and Expertise

Professor Emeritus, Pharmaceutical and Medicinal Chemistry Department, National Research Center, Cairo, Egypt

Vu Dang Hoang

Vu Dang Hoang completed his doctorate in pharmaceutics at the University of Strathclyde, UK, in 2005 and conducted postdoctoral research at the Ecole Nationale d'Ingénieurs des Techniques des Industries Agricoles et Alimentaires, France, in 2006. He has been lecturing at the Department of Analytical Chemistry and Toxicology, Hanoi University of Pharmacy, Vietnam, since 2007. He became an associate professor in the field of drug quality control in 2015. His research interests include chemico-physical characterization of topical drug delivery systems and chemometrics-based methods for the analysis of drugs in pharmaceutical dosage forms and biological fluids. So far, he has authored more than 30 publications in pharmaceutical research and analytical chemistry in leading national and international peer-reviewed journals.

Affiliations and Expertise

Associate Professor, Department of Analytical Chemistry and Toxicology, Hanoi University of Pharmacy, Hanoi, Vietnam

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