Veterinary Toxicology

2nd Edition

Basic and Clinical Principles

Editors: Ramesh C. Gupta
Hardcover ISBN: 9780123859266
eBook ISBN: 9780123859273
Imprint: Academic Press
Published Date: 15th March 2012
Page Count: 1454
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Veterinary Toxicology is a unique single reference that teaches the basic principles of veterinary toxicology to any student at the DVM, MS or PhD level and will continue to serve as a clinical reference for practicing veterinary toxicologists, poison control centers, marine biologists, environmentalists, and animal scientists. While most comparable texts are primarily directed toward the field of human toxicology, this is the one text needed to thoroughly prepare future veterinarians on the newest approaches for diagnosing poisoning cases in all animals from chemicals and plants of a diverse nature as a result of inadvertent, accidental, or malicious intents. Many chapters are provided on topics not covered in any previous books such as target organ toxicity, radiation and radioactive materials, FDA regulatory issues, and ethics in veterinary toxicology.

Key Features

  • Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries
  • New chapters covering important and timely topics such as melamine and cyanuric acid, toxicogenomics, toxic gases and veterinary medical geology
  • Expanded look at international topics, such as epidemiology of animal poisonings, regulatory guidelines and poisonous plants in Europe
  • Heavily contributed book with chapters written by qualified and well-experienced authorities across all areas of veterinary toxicology
  • Problem solving strategies are offered for treatment as well as in-depth knowledge of the basic mechanisms of veterinary toxicology


Practitioners, professors and students of veterinary medicine and veterinary toxicology, poison control centers, marine biologists, environmentalists and animal scientists.

Table of Contents



List of Contributors

SECTION I. General

Chapter 1. Veterinary toxicology

The emergence of veterinary toxicology

Professional organization and academic recognition of veterinary toxicology

Published veterinary toxicology literature

…And where will veterinary toxicology go from here?

Chapter 2. Concepts in veterinary toxicology


Historical perspective

Evolution of veterinary toxicology

A framework for acquiring information

Sources of information

Toxicologic descriptors

Conclusions and summary



Chapter 3. Toxicokinetics


Underlying physiology

Traditional (compartmental) toxicokinetic models

Physiologically based toxicokinetics


Chapter 4. Factors affecting chemical toxicity


Individual factors

Non-individual factors


Chapter 5. Toxicological testing


In vivo models in toxicity testing

In vitro models of toxicity testing

General summary and conclusions

Chapter 6. Epidemiology of animal poisonings in the United States






Other species

Agents involved

Signs and outcomes


Chapter 7. Epidemiology of animal poisonings in Europe


Species involved

Toxic classes

Non-metals and metalloids




Feed associated toxicants

Drugs and related compounds

Household products



Chapter 8. Chemicals of terrorism


Chlorine gas


Mustard gas


Phosgene oxime

Cyanide and hydrogen cyanide



No. of pages:
© Academic Press 2012
Academic Press
Hardcover ISBN:
eBook ISBN:

About the Editor

Ramesh C. Gupta

Dr. Ramesh C. Gupta, Professor & Head of Toxicology Department at Murray State university, is engaged in experimental brain research in relation to Alzheimer(s) disease (AD) and pesticide toxicity. He has delivered lectures in Australia, Italy, Japan, Germany, France, Switzerland, Spain, Czech Republic, China, South Korea, and Sweden. He served the panels of NIH, CDC, NIOSH, and NAS. He has >350 publications to his credit, including six major books: (1) Toxicology of Organophosphate and Carbamate Compounds, (2) Veterinary Toxicology: Basic and Clinical Principles, (3) Handbook of Toxicology of Chemical Warfare Agents, (4) Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology, (5) Reproductive and Developmental Toxicology, and (6) Biomarkers in Toxicology. He is recipient of Murray State University's distinguished researcher award of the year-2006. He is a diplomate of American Board of Toxicology, and fellow of American College of Toxicology, American College of Nutrition, and Academy of Toxicological Sciences.

Affiliations and Expertise

DVM, MVSc, PhD, DABT, FACT, FACN, FATS, Professor and Head, Toxicology Department, Breathitt Veterinary Center, Murray State University, Hopkinsville, KY, USA


Doody’s Core Titles 2013, Doody Enterprises


Praise for the 2nd Edition:

"The stated purpose of the second edition of Veterinary Toxicology: Basic and Clinical Principles is to serve as a comprehensive, expert-authored resource for toxicologists and other scientists and for use as a textbook in the classroom. The book covers the wide breadth of veterinary toxicology with exceptional depth. Topics range from the history of veterinary toxicology to nanoparticles, pesticides, metals, laws, regulatory considerations, diagnostic testing, and plant and environmental toxicology. The authors do an exceptional job of addressing pharmacokinetics and mechanisms of action in detail. Principles of analytic toxicology and sample submission are adequately covered.


Agents encountered as a result of natural and man-made disasters are a key focus of the reference.  The text does not contain in-depth information in the area of human pharmaceuticals, which is a common source of exposure for family pets.  Treatment details and differential diagnosis lists are limited.  Clearly, the book delivers on its purpose as a key reference for scientists and students, covering the complex topic of veterinary toxicology in a comprehensive, well-designed format.  Although this book is a tremendous addition to any library, veterinarians, other scientists, and students who seek details on the varied and complex topic of veterianry toxicology will find this reference a must-have book." -Reviewed by Steven Hansen, DVM, MS, MBA, DABVT, in the Journal of American Veterinary Medical Association


Praise for the 1st Edition:

"A unique single reference that teaches the basic principles of veterinary toxicology to any student at the DVM, MS or PhD level and will continue to serve as a clinical reference for practicing veterinary toxicologists, poison control centers, marine