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Vertebrate Endocrinology - 5th Edition - ISBN: 9780123948151, 9780123964656

Vertebrate Endocrinology

5th Edition

5.0 star rating 1 Review
Authors: David Norris James Carr
eBook ISBN: 9780123964656
Hardcover ISBN: 9780123948151
Imprint: Academic Press
Published Date: 20th June 2013
Page Count: 580
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Vertebrate Endocrinology represents more than just a treatment of the endocrine system-it integrates hormones with other chemical bioregulatory agents not classically included with the endocrine system. It provides a complete overview of the endocrine system of vertebrates by first emphasizing the mammalian system as the basis of most terminology and understanding of endocrine mechanisms and then applies that to non-mammals. The serious reader will gain both an understanding of the intricate relationships among all of the body systems and their regulation by hormones and other bioregulators, but also a sense of their development through evolutionary time as well as the roles of hormones at different stages of an animal's life cycle.

Key Features

  • Includes new full color format includes over 450 full color, completely redrawn image
  • Features a companion web site hosting all images from the book as PPT slides and .jpeg files
  • Presents completedly updated and revitalized content with new chapters, such as Endocrine Disrupters and Behavioral Endocrinology
  • Offers new clinical correlation vignettes throughout


Graduate students and advanced undergraduates in the biological sciences, animal sciences, & veterinary sciences; endocrine researchers in comparative, veterinary, and mammalian endocrinology

Table of Contents

1. An Overview of Chemical Bioregulation in Vertebrates

I. The Comparative Vertebrate Approach

II. The Origins of Bioregulation

III. Categories of Bioregulators

IV. General Organization of Bioregulatory Systems

V. Cell and Tissue Organization of Bioregulatory Systems

VI. Homeostasis

VII. Organization and Goals for This Textbook

Study Questions

Suggested Reading

2. Methods to Study Bioregulation

I. The Scientific Method

II. Methods of Endocrine Analysis

III. Molecular Biology and Bioregulation

IV. Animal Models

Study Questions

Suggested Reading

3. Synthesis, Metabolism, and Actions of Bioregulators

I. Amino Acids, Amines, Peptides, and Proteins

II. Steroid Bioregulators

III. Thyroid Hormones

IV. Eicosanoids

V. Summary

Study Questions

Suggested Reading

4. Organization of the Mammalian Hypothalamus—Pituitary Axes

I. The Mammalian Pituitary

II. The Mammalian Hypothalamus

III. Tropic Hormones of the Adenohypophysis

IV. Regulation of Tropic Hormone Secretion in Mammals

V. The Nonapeptide Hormones

VI. The Pineal Gland

VII. Clinical Aspects of the NeuroendocrineSystem

VIII. Summary

Study Questions

Suggested Readings

5. The Hypothalamuse Pituitary System in Non-Mammalian Vertebrates

I. The Pituitary Gland of Fishes: Anatomical Considerations

II. The Pituitary of Tetrapod Vertebrates: Anatomical Considerations

III. The Hypothalamus of Non-Mammalian Vertebrates

IV. Tropic Hormones of Non-Mammalian Vertebrates

V. Comparative Aspects of Hypothalamic Control of Pituitary Function in Non-Mammals

VI. Nonapeptide Neurohormones of the Non-Mammalian Pars Nervosa

VII. The Epiphysial Complex of Non-Mammals

VIII. Summary

Study Questions

Suggested Reading

6. The Hypothalamus—Pituitary—Thyroid (HPT) Axis of Mammals

I. Some Historical Aspects of Thyroid Physiology

II. Development and Organization of the Mammalian Thyroid Gland

III. Synthesis, Secretion, Action, and Metabolism of Thyroid Hormones

IV. Factors That Influence Thyroid Function in Mammals

V. Biological Actions of Thyroid Hormones in Mammals

VI. Clinical Aspects of Thyroid Function

VII. Summary

Study Questions

Suggested Reading

7. The Hypothalamuse—Pituitary—Thyroid (HPT) Axis of Non-Mammalian Vertebrates

I. Evolution of the Thyroid Gland and Its Functions

II. Comparative Thyroid Physiology

III. Summary

Study Questions

Selected Reading

8. The Mammalian Adrenal Glands: Cortical and Chromaffin Cells

I. The Mammalian Adrenal Cortex

II. Biosynthesis and Transport of Corticosteroids

III. Secretion and Actions of Glucocorticoids

IV. Allostasis and Allostatic Load

V. Aldosterone: The Principal Mammalian ""Mineralocorticoid""

VI. Endocrine Disruption of Adrenal Cortex Function

VII. Clinical Aspects of the Adrenal Axis

VIII. The Mammalian Adrenal Medulla

IX. Summary

Study Questions

Suggested Reading

9. Comparative Aspects of Vertebrate Adrenals

I. Comparative Aspects of Adrenocortical Tissue

II. Physiological Roles for Corticosteroids in Non-Mammalian Vertebrates

III. RenineAngiotensin System in Non-Mammals

IV. Natriuretic Peptides (NPs) in Non-Mammalian Vertebrates

V. Evolution of Chromaffin Tissue and Adrenal Medullary Hormones

VI. Endocrine Disruption of Corticosteroid Functions in Non-Mammalian Vertebrates

VII. Summary

Study Questions

Suggested Reading

10. The Endocrinology of Mammalian Reproduction

I. General Features of Mammalian Reproduction

II. Reproduction in Monotremes and Marsupials

III. Reproduction in Eutherian Mammals

IV. Endocrine Regulation in Eutherian Males

V. Endocrine Regulation in Eutherian Females

VI. Reproductive Cycles in Selected Eutherian Females

VII. Endocrine Disruptors and Mammalian Reproduction

VIII. Major Human Endocrine Disorders Related to Reproduction

IX. Summary

Study Questions

Suggested Reading

11. Comparative Aspects of Vertebrate Reproduction

I. Some General Features of Vertebrate Reproduction

II. Reproduction in Agnathan Fishes: Cyclostomes

III. Reproduction in Chondrichthyean Fishes

IV. Reproduction in Bony Fishes

V. Reproduction in Amphibians

VI. Reproduction in Reptiles

VII. Reproduction in Birds

VIII. Endocrine Disruption of Reproduction in Non-Mammalian Vertebrates

IX. Summary

Study Questions

Suggested Reading

12. Chemical Regulation of Feeding, Digestion and Metabolism

I. Regulation of Feeding

II. Regulation of Digestion

III. The Mammalian Pancreas

IV. Hormones Regulating Mammalian Metabolism

V. Clinical Aspects of Pancreatic Function

VI. Summary

Study Questions

Suggested Reading

13. Comparative Aspects of Feeding, Digestion, and Metabolism

I. Hormones and Feeding in Non-Mammals

II. Hormones and Digestion in Non-Mammals

III. Comparative Aspects of the Endocrine Pancreas

IV. Summary

Study Questions

Suggested Reading

14. Regulation of Calcium and Phosphate Homeostasis

I. Importance of Calcium and Phosphate

II. Bone Formation and Resorption in Mammals

III. Endocrine Regulation of Calcium and Phosphate Homeostasis in Mammals

IV. Major Clinical Disorders Associated with Calcium Metabolism

V. Calcium and Phosphate Homeostasis in Non-Mammalian Vertebrates

VI. Summary

Study Questions

Suggested Reading



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© Academic Press 2013
20th June 2013
Academic Press
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About the Authors

David Norris

Dr. David O. Norris (B.S., Baldwin Wallace University, 1961; PhD 1966, University of Washington) was a professor at the University of Colorado for 46 years where he studied environmental endocrinology of fishes and amphibians and taught general biology, endocrinology, human physiology, histology, vertebrate biology, and forensic biology. His endocrine research interests involve the role of natural and anthropogenic factors (pollutants) that operate through the brain and pituitary to influence thyroid, adrenal, and reproductive physiology that in turn affect development, sexual differentiation, reproduction, and aging. He retired from CU in 2012 and currently is Professor Emeritus of the Department of Integrative Physiology. Dr. Norris also does research in forensic botany and consults with law enforcement groups on homicides and other crimes throughout the USA and in several other countries He is a Fellow of the American Academy of Forensic Sciences Dr. Norris has published more than 150 scientific papers and abstracts in environmental endocrinology and forensic botany and is the senior author on several books including Vertebrate Endocrinology (6th edition, Academic Press, 2020), Endocrine Disruption: Implications for Health of Wildlife and Humans (Oxford University Press, 2005), a five-volume work on Hormones and Reproduction of Vertebrates (Academic Press, 2011) and Forensic Plant Science (Academic Press, 2016).

Affiliations and Expertise

Professor of Integrative Physiology, University of Colorado, Boulder, CO, USA

James Carr

Dr. James A. Carr is a Professor of Biology in the Department of Biological Sciences at Texas Tech University. His research has focused on various aspects of environmental endocrinology and neuroendocrinology for 25 years including the effects of opioid peptides on brainstem, cardiovascular areas and pituitary hormone secretion, the impact of environmental pollutants on the thyroid and reproductive axes in fishes and amphibians, and the impact of stress hormones on subcortical visual pathways involved in feeding.

Affiliations and Expertise

Professor and Faculty Director, Joint Admission Medical Program, Department of Biological Sciences Texas Tech University, Lubbock, TX, USA


"…what makes this book particularly useful for many aspects of the study of life science lies in its synthesis, its making of links between different aspects of biology."--The Biologist,Vol 61, No 6

"This book will be useful for graduate students interested in comparative endocrinology…As an instructor of veterinary endocrinology, I found this book to be a good source for both illustrations and basic information, and a complement for clinical and animal management discussions in endocrinology."--Journal of American Veterinary Medicine Association, December 15, 2013
"…constitutes a major and unique contribution to this area…contains a wealth of factual information…[and] admirably succeeds in stimulating the scientific curiosity of readers and in conveying a sense of fascination for the intricate mechanisms and importance of endocrinology."--General and Comparative Endocrinology
"…a good text for comparative endocrinology classes or classes composed of students from a wide variety of disciplines…this book is well written and organized. Concepts are explained in a manner that should be easily understandable to beginning endocrinology students."--Trends in Endocrinology and Metabolism

Ratings and Reviews