Updates on Osteoporosis, An Issue of Endocrinology and Metabolism Clinics of North America

1st Edition, Volume 50-2 - May 31, 2021
Editor: Pauline M. Camacho
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 7 9 5 5 1 - 7
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 7 9 5 5 2 - 4

In this issue of Endocrinology and Metabolism Clinics, Guest Editor Pauline Camacho brings her considerable expertise to the topic of Osteoporosis.… Read more

Updates on Osteoporosis, An Issue of Endocrinology and Metabolism Clinics of North America

Purchase options

Info / Buy

LIMITED OFFER

Save 50% on book bundles

Immediately download your ebook while waiting for your print delivery. No promo code is needed.

Institutional subscription on ScienceDirect

Request a sales quote

In this issue of Endocrinology and Metabolism Clinics, Guest Editor Pauline Camacho brings her considerable expertise to the topic of Osteoporosis.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Foreword
Preface
Postmenopausal Osteoporosis: Latest Guidelines
Key points
Osteoporosis
Diagnosis
Treatment
Antiresorptive agents
Anabolic agents
Romosozumab
Summary
Clinics care points
Update on Approved Osteoporosis Therapies Including Combination and Sequential Use of Agents
Key points
Introduction
Bone anti-resorptive agents
Estrogen/selective estrogen receptor modulators
Bone anabolic agents
Teriparatide
Abaloparatide
Romosozumab
Combination and sequential therapy
Summary
Clinics care points
Update on Rare Adverse Events from Osteoporosis Therapy and Bisphosphonate Drug Holidays
Key points
Introduction
Efficacy studies and effect of discontinuation
Common side effects of bisphosphonate treatment
Less common side effects of bisphosphonate treatment
Approach to treat osteoporosis, prevent fractures, and avoid side effects
Summary
Clinics care points
Denosumab Discontinuation in Patients Treated for Low Bone Density and Osteoporosis
Key points
Introduction
Efficacy of denosumab therapy
Denosumab discontinuation: bone mineral density changes
Denosumab discontinuation: fracture risk
Sequential antiresorptive therapy after denosumab discontinuation
When should denosumab be discontinued?
Approach to denosumab discontinuation
Summary
Clinics Care Points
Role of Bone Turnover Markers in Osteoporosis Therapy
Key points
Introduction
Definition
Dual-energy X-ray absorptiometry DXA scan limitations
Role of bone turnover markers
Standardized bone turnover markers are N-terminal propeptide of type I collagen and C-terminal telopeptide of type I collagen
C-terminal telopeptide of type I collagen
N-terminal propeptide of type I collagen
Other bone turnover markers
Causes of preanalytic variability in bone turnover markers
Medical conditions with low bone turnover
Medical conditions with high bone turnover
Medical conditions with predominantly high bone resorption
Medications and bone turnover
Statistical interpretation of bone turnover markers
Fracture risk prediction
Fracture prediction in high-risk populations
Monitoring bisphosphonate therapy
Role in bisphosphonate holiday
Monitoring denosumab therapy
Monitoring anabolic therapy
Summary
Clinics care points
Updates on Osteoporosis in Men
Key points
Introduction
Epidemiology
Diagnosis
Evaluation
Treatment
Conclusion
Clinics care points
Glucocorticoid- and Transplantation-Induced Osteoporosis
Key points
Introduction
Glucocorticoid-induced osteoporosis
Transplantation-induced osteoporosis
Summary
Clinics care points
Diabetes and Osteoporosis: Part I, Epidemiology and Pathophysiology
Key points
Background
Epidemiology
Risk factors for fracture
Pathophysiology
Antidiabetic medications
Summary
Clinics care points
Diabetes and Osteoporosis: Part II, Clinical Management
Key points
Background
Fracture risk assessment
Management
Summary
Clinics care points
Assessment of Skeletal Strength: Bone Density Testing and Beyond
Key points
Introduction
Bone density testing
Ultrasound measurements
Imaging for vertebral fractures
Fracture risk algorithms
Measurements of bone structure
Reference point indentation
Future perspectives
Summary
Clinics care points

Purchase options

Save 50% on book bundles

Institutional subscription on ScienceDirect

Pauline M. Camacho