Unity and Diversity in Biochemistry

Unity and Diversity in Biochemistry

An Introduction to Chemical Biology

1st Edition - January 1, 1960

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  • Author: Marcel Florkin
  • eBook ISBN: 9781483280967

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International Series of Monographs on Pure and Applied Biology, Volume 1: Unity and Diversity in Biochemistry focuses on the advancements of processes, techniques, methodologies, and approaches involved in biochemistry. The publication first offers information on the constituents of the biosphere, modes of linkage by covalent bonds and macromolecules, general principles of biochemical energetics, and enzymes. The text then examines the destructive and non-destructive methods in modern biochemistry, priming reactions, and biosynthesis. Discussions focus on the mechanisms for the breakdown of amino acids, glycolysis and the hexosemonophosphate shunt, interrelations between priming reactions, respiratory chains, biochemical investigation and use of isotopes, and use of mutant strains micro-organisms. The manuscript takes a look at cellular topochemistry and regulation, aspects of biochemical diversity, inheritance of biochemical characteristics, and biochemical evolution. Topics include evolution of biochemical systems and constituents, control of biochemical characteristics by genes, biochemical differentiation of cells in a single organism, and factors which determine the velocity and path of enzymatic reaction chains. The selection is a dependable source of data for biochemists and readers interested in the different aspects of biochemistry.

Table of Contents

  • Translator's Preface


    Part One

    Chapter I: The Biosphere

    Chapter II: Constituents of the Biosphere

    I. The Three Principal Biochemical Structures

    II. Other Chemical Structures of General Interest

    Chapter III: Modes of Linkage by Covalent Bonds

    I. "Oside" Linkage

    II. Ester Linkage (and Anhydride Linkage)

    III. Peptidebond

    Chapter IV: Macromolecules

    I. Polysaccharides

    II. Proteins

    III. Nucleoproteins

    IV. Metalloproteins

    V. Lipoproteins

    Part Two—Enzymes and Biochemical Energetics

    Chapter I: General Principles of Biochemistry

    I. Free Energy

    II. Energy Coupling

    III. Energy rich bonds

    IV. The Phosphate Cycle

    V. Biological Oxido-Reductions and the Generation of Energy-Rich Bonds

    VI. The Cellular Dynamo

    VII. The Pyrophosphate Bond and Cellular Work

    VIII. Chemical Equilibrium and the Stationary State

    Chapter II: Enzymes

    I. Definition

    II. Enzymes and Activators

    III. Classification of Enzymes

    IV. Kinetics

    V. The Mechanism of Action of Enzymes and Coenzymes

    Part Three—Chemical Reactions in the Biosphere


    Chapter I: Destructive and Non-Destructive Methods in Modern Biochemistry

    I. From the Whole Organism to the Pure Enzyme

    II. Biochemical Investigation and the Use of Isotopes

    III. The Use of Mutant Strains of Micro-Organisms

    Chapter II: Priming Reactions

    I. Glycolysis and the Hexosemonophosphate Shunt

    II. Another Pathway for the Production of Acetyl-CoA: The Fatty Acid Cycle

    III. The tricarboxylic acid cycle

    IV. Respiratory Chains

    V. Mechanisms for the Breakdown of Amino Acids

    VI. Interrelations Between Priming Reactions

    VII. Energetics of the Priming Reactions

    Chapter III: Biosyntheses

    I. The Materials for Biosyntheses

    II. Biosynthesis

    Part Four—Topobiochemistry and Cellular Regulation

    Chapter I: Cellular Topochemistry

    Chapter II: Cellular Regulation

    I. Factors Which Determine the Velocity and the Path of Enzymatic Reaction Chains

    II. The Pasteur Effect

    III. The Genetic Control of the Relative Rates of Enzymatic Reactions

    Part Five—Biochemical Diversity

    Chapter I: Some Aspects of Biochemical Diversity

    I. Terpenes

    II. Porphyrins

    III. Protein Macromolecules

    Chapter II: The Inheritance of Biochemical Characteristics

    I. Control of Biochemical Characteristics by Genes

    II. Biochemical Differentiation of Cells in a Single Organism

    III. Phenotype and "Milieu"

    Chapter III: Biochemisty and Taxonomy

    I. Biochemical Diversity

    II. Diversity within Species

    III. Diversity Between Species

    Chapter IV: Biochemical Evolution

    I. Definition

    II. Evolution of Biochemical Constituents

    III. Evolution of Biochemical Systems

    Part Six—The Metabolism of the Biosphere


    Chapter I: Entry into the Biosphere

    I. Carbon and Energy

    II. Phosphorus

    III. Nitrogen

    IV. Sulphur

    Chapter II: Departure from the Biosphere

    I. Ammonification in the Soil

    II. The Exit of Carbon from the Biosphere

    Chapter III: The Cycles

    I. The Carbon Cycle

    II. The Nitrogen Cycle

    III. The Sulphur Cycle

    IV. The Circulation of Phosphorus

    V. The Metabolism of the Biosphere


Product details

  • No. of pages: 414
  • Language: English
  • Copyright: © Pergamon 1960
  • Published: January 1, 1960
  • Imprint: Pergamon
  • eBook ISBN: 9781483280967

About the Author

Marcel Florkin

About the Editors

P. Alexander

Z. M. Bacq

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