Ultrastructure of Rat Adenohypophysis

Correlation with Function

1st Edition - January 1, 1973
Author: Allen Costoff
Language: English
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 1 5 9 5 7 - 9

Ultrastructure of Rat Adenohypophysis: Correlation with Function discusses the ultrastructure of the anterior pituitary in the normal intact rat, as well as in animal after various… Read more

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Ultrastructure of Rat Adenohypophysis: Correlation with Function discusses the ultrastructure of the anterior pituitary in the normal intact rat, as well as in animal after various treatments and changes in its physiology. Wherever possible, the book attempts to coordinate and associate changes in pituitary ultrastructure with physiological aspects. The book also presents a method for the isolation of various populations of pituitary secretory granules that can be used in experimental endocrinological research. It also discusses the various cell types, including the chromophobe; the pars tuberalis and pars intermedia of the adenohypophysis; and the chemical and physical properties of the secretory granules and their formation and release. This reference will serve as a guide for pituitary ultrastructural studies in other species. It is valuable to students and experienced investigators in the field of endocrinology, anatomy, pathology, physiology, biochemistry, and related disciplines.

Preface

Abbreviations and Terminology Used in Text

Abbreviations used in Electron Micrograph Descriptions

Chapter 1 Introduction

Text

References

Chapter 2 Experimental Procedures Animals

Preparation of Tissues for Electron Microscopic Study

Preparation of Pituitary Granules

Biological Assays

References

Chapter 3 Thyrotropes

Light Microscopy

Ultrastructure of Thyrotropes

Discussion

TSH Content of Pituitary Granule Fractions

References

Chapter 4 Gonadotropes

Light Microscopy of Gonadotropes

Ultrastructure of Gonadotropes

Discussion of Gonadotropes

FSH and L H Activity of Isolated Secretory Granule Fractions

References

Chapter 5 Adrenocorticotropes

Light Microscopy

Electron Microscopy

Metopirone

Amphenone

Dexamethasone

Adrenal Cortical Steroids

Exogenous ACTH

a-Ethyltryptamine

Corticotropes after Adrenalectomy and Castration

General Discussion of Corticotropes

Biological Activities of Pituitary Granule Fractions

References

Chapter 6 Somatotropes

Light Microscopy

Ultrastructure of Somatotropes

Discussion of Ultrastructural Findings

Somatotropic Activities of Granule Fractions

References

Chapter 7 Mammotropes

Light Microscopy

Ultrastructure of the Mammotrope in Intact and Treated Rats

Pituitary Autografts

References

Chapter 8 Chromophobes

Electron Microscopy of Chromophobes

References

Chapter 9 Pars Tuberalis

Histochemical Studies

Recent Histochemistry, Immunochemistry, and Electron Microscopy of the Pars Tuberalis

References

Chapter 10 Pars Intermedia

Hypophyseal Cleft

Cells of the Central Region of the Pars Intermedia

Cells of the Pars Intermedia after Pituitary Is Autografted to the Kidney Capsule

Other Hormones of the Pituitary Gland

References

Chapter 11 Hormonal Activities and Biochemical Properties of Isolated Granule Fractions

Biological Activities of Granule Fractions

Biochemical and Physical Properties of Granules

References

Chapter 12 Synthesis, Storage, and Release of Anterior Pituitary Hormones

Formation of Secretory Granules

Release of Pituitary Secretory Granules

Summary of Synthesis and Release of Anterior Pituitary Hormones

References

Author Index

Subject Index