Ultrastructure of Rat Adenohypophysis

Ultrastructure of Rat Adenohypophysis

Correlation with Function

1st Edition - January 1, 1973

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  • Author: Allen Costoff
  • eBook ISBN: 9780323159579

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Description

Ultrastructure of Rat Adenohypophysis: Correlation with Function discusses the ultrastructure of the anterior pituitary in the normal intact rat, as well as in animal after various treatments and changes in its physiology. Wherever possible, the book attempts to coordinate and associate changes in pituitary ultrastructure with physiological aspects. The book also presents a method for the isolation of various populations of pituitary secretory granules that can be used in experimental endocrinological research. It also discusses the various cell types, including the chromophobe; the pars tuberalis and pars intermedia of the adenohypophysis; and the chemical and physical properties of the secretory granules and their formation and release. This reference will serve as a guide for pituitary ultrastructural studies in other species. It is valuable to students and experienced investigators in the field of endocrinology, anatomy, pathology, physiology, biochemistry, and related disciplines.

Table of Contents


  • Preface

    Abbreviations and Terminology Used in Text

    Abbreviations used in Electron Micrograph Descriptions

    Chapter 1 Introduction

    Text

    References

    Chapter 2 Experimental Procedures Animals

    Preparation of Tissues for Electron Microscopic Study

    Preparation of Pituitary Granules

    Biological Assays

    References

    Chapter 3 Thyrotropes

    Light Microscopy

    Ultrastructure of Thyrotropes

    Discussion

    TSH Content of Pituitary Granule Fractions

    References

    Chapter 4 Gonadotropes

    Light Microscopy of Gonadotropes

    Ultrastructure of Gonadotropes

    Discussion of Gonadotropes

    FSH and L H Activity of Isolated Secretory Granule Fractions

    References

    Chapter 5 Adrenocorticotropes

    Light Microscopy

    Electron Microscopy

    Metopirone

    Amphenone

    Dexamethasone

    Adrenal Cortical Steroids

    Exogenous ACTH

    a-Ethyltryptamine

    Corticotropes after Adrenalectomy and Castration

    General Discussion of Corticotropes

    Biological Activities of Pituitary Granule Fractions

    References

    Chapter 6 Somatotropes

    Light Microscopy

    Ultrastructure of Somatotropes

    Discussion of Ultrastructural Findings

    Somatotropic Activities of Granule Fractions

    References

    Chapter 7 Mammotropes

    Light Microscopy

    Ultrastructure of the Mammotrope in Intact and Treated Rats

    Pituitary Autografts

    References

    Chapter 8 Chromophobes

    Electron Microscopy of Chromophobes

    References

    Chapter 9 Pars Tuberalis

    Histochemical Studies

    Recent Histochemistry, Immunochemistry, and Electron Microscopy of the Pars Tuberalis

    References

    Chapter 10 Pars Intermedia

    Hypophyseal Cleft

    Cells of the Central Region of the Pars Intermedia

    Cells of the Pars Intermedia after Pituitary Is Autografted to the Kidney Capsule

    Other Hormones of the Pituitary Gland

    References

    Chapter 11 Hormonal Activities and Biochemical Properties of Isolated Granule Fractions

    Biological Activities of Granule Fractions

    Biochemical and Physical Properties of Granules

    References

    Chapter 12 Synthesis, Storage, and Release of Anterior Pituitary Hormones

    Formation of Secretory Granules

    Release of Pituitary Secretory Granules

    Summary of Synthesis and Release of Anterior Pituitary Hormones

    References

    Author Index

    Subject Index






Product details

  • No. of pages: 234
  • Language: English
  • Copyright: © Academic Press 1973
  • Published: January 1, 1973
  • Imprint: Academic Press
  • eBook ISBN: 9780323159579

About the Author

Allen Costoff

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