Tumor Vascularization

Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a valuable source for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in tumor progression and blood vessels.

• Explains new, non-orthodox concepts recently developed and related to the modality of growth of tumor blood vessels
• Provides information on the types of angiogenesis, non-angiogenesis dependent growth and vascular co-option, discussing both their similarities and differences
• Encompasses a discussion on clinical implications of tumor vascularization to translate research findings into treatment

cancer researchers, medical scientists, clinicians, graduate students

Preface
Domenico Ribatti and Francesco Pezzella
1. Sprouting and non-sprouting angiogenesis in tumors
Domenico Ribatti and Francesco Pezzella
2. Nonangiogenic tumor growth
Peter Vermeulen and Francesco Pezzella
3. Vascular co-option
Pedro García-Gómez and Manuel Valiente
4. Pericyte mimicry: an embryonic-like mechanism for tumor metastasis
Claire Lugassy, Hynda Kleinman and Raymond Barnhill
5. Vasculogenic mimicry
Yun Cao and Chao-Nan Miles Qian
6. Postnatal vasculogenesis
Latetitia Andrique, Gaelle Recher, Pierre Nassoy and Andreas Bikfalvi
7. The perivascular niche
Alia Komsany and Francesco Pezzella
8. Zebrafish as an experimental model to study tumor angiogenesis
Jessica Guerra, Chiara Tobia, Marco Presta and Andrea Barbieri
9. Clinical implications
Adrian Harris