Translational Autoimmunity, Volume 6

Translational Autoimmunity, Volume 6

Advances in Autoimmune Rheumatic Diseases

1st Edition - February 1, 2023

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  • Editor: Nima Rezaei
  • Paperback ISBN: 9780323858311

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Translational Autoimmunity: Advances in Autoimmune Rheumatic Diseases, Volume Six addresses autoimmune diseases classified under the category of rheumatic diseases. Rheumatic diseases are heterogeneous groups of disorders in which inflammation affects not only joints, but also tendons, ligaments and bones. This updated release focuses on immunopathogenesis and clinical and laboratory details of rheumatic diseases, including rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, osteoarthritis and Sjogren’s syndrome, and will be of interest to researchers, students and clinicians interested in autoimmune diseases, especially rheumatic diseases. From an introduction to rheumatic diseases to diagnostic laboratory tests, and from the microbiota-immunity to cell-based therapies, the bench to bedside approach to rheumatic diseases is the main subject of discussion in this comprehensive resource.

Key Features

  • Gives an introduction on rheumatic diseases, from bench to bedside
  • Describes diagnostic laboratory tests in rheumatic diseases
  • Meets the needs of basic scientists, clinicians and translational scientists and industry partners
  • Focuses on immunopathogenesis and clinical and laboratory details of rheumatic diseases


Clinical immunologists, Rheumatologist, Endocrinologists, Microbiologists, Neurologists, Oncologists, Rheumatologists, Clinicians, research scientists, and industry partners

Table of Contents

  • 1. Introduction on Autoimmune Rheumatic Diseases
    2. Bone health in autoimmune inflammatory rheumatic diseases
    3. Rheumatic diseases: from bench to bedside
    4. Rheumatic fever: from pathogenesis to vaccine perspectives
    5. Changes in future rheumatoid arthritis treatment in the light of Epstein-Barr virus infection
    6. Rheumatologic diseases: the microbiota-immunity axis in development and treatment
    7. The diagnostic laboratory tests in rheumatic diseases
    8. Autoantibody profiling in autoimmune rheumatic diseases: from basic research to clinical use
    9. Air pollution and rheumatoid arthritis: current knowledge and state-of-the-art
    10. Advanced therapies for rheumatoid arthritis
    11. A tolerogenic dendritic cell-based therapy targeting heat shock protein specific regulatory T cells in rheumatoid arthritis
    12. T-cell large granular lymphocytic leukemia in the setting of rheumatoid arthritis
    13. Biomaterials as tools for re-balancing the skewed immunity in rheumatoid arthritis
    14. Immunopathogenesis of systemic lupus erythematosus
    15. Challenges in systemic lupus erythematosus: from bench to bedside
    16. Therapeutic potential in systemic lupus erythematosus
    17. The pathology and potential clinical applicability of interfering T cells in systemic lupus erythematosus
    18. Rheumatic chorea
    19. Management of the rheumatoid hind foot and ankle
    20. Immunopathogenesis of scleroderma
    21. Skin manifestations and autoimmune disturbances in dermatomyositis
    22. T cells in systemic sclerosis
    23. Etiopathogenesis of Behçet's disease: the role of genetic, immunological and environmental factors
    24. Interleukin-1 family in Behçet's disease: inflammatory and anti-inflammatory mediators
    25. Salivary gland regeneration and repair in Sjogren’s syndrome
    26. Translational regulation of bone and joint inflammation by type 2 innate lymphoid cells
    27. Arboviruses (Alphavirus) related to autoimmune rheumatic diseases: Triggers and possible therapeutic interventions
    28. Rheumatologic manifestations of autoinflammatory disorders

Product details

  • No. of pages: 316
  • Language: English
  • Copyright: © Academic Press 2023
  • Published: February 1, 2023
  • Imprint: Academic Press
  • Paperback ISBN: 9780323858311

About the Editor

Nima Rezaei

Professor Nima Rezaei gained his medical degree (MD) from Tehran University of Medical Sciences and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Professor Rezaei is now the Full Professor of Immunology and Vice Dean of Research, School of Medicine, Tehran University of Medical Sciences, and the co-founder and Head of the Research Center for Immunodeficiencies. He is also the founding President of the Universal Scientific Education and Research Network (USERN). Professor Rezaei has already been the Director of more than 55 research projects and has designed and participated in several international collaborative projects. Professor Rezaei is an editorial assistant or board member for more than 30 international journals. He has edited more than 35 international books, has presented more than 500 lectures/posters in congresses/meetings, and has published more than 1,000 scientific papers in the international journals.

Affiliations and Expertise

Professor, Department of Immunology, School of Medicine; Head, Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences; Founding President, Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran

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