- Contains a comprehensive collection of transgenic animal and gene transfer methods
- Discusses background and introduction to techniques and animal systems
- Teaches practical step-by-step protocols
- Describes mouse model systems
- Covers laboratory and domestic animal species
- Illustrated with diagrams and photographs
- Includes useful tables and charts
Table of Contents
C.A. Pinkert, Introduction to Transgenic Animals.
Transgenic Animal Production Focusing on the Mouse Model:
H.G. Polites and C.A. Pinkert, Transgenic Animal Production Using DNA Microinjection.
P. Overbeek, Factors Affecting Transgenic Animal Production.
T. Doetschman, Gene Transfer in Embryonic Stem Cells.
P.A. Wood, Retrovirus-Mediated Gene Transfer.
G.M. Monastersky, Gene Transfer Technology: Alternative Techniques and Applications.
B.T. Tinkle, C.J. Bieberich, and G. Jay, Molecular Approaches Involved in Mammalian Gene Transfer: Analysis of Transgene Integration.
C.J. Bieberich, L. Ngo, and G. Jay, Molecular Approaches Involved in Mammalian Gene Transfer: Analysis of Transgene Expression.
Production of Transgenic Laboratory and Domestic Animal Species:
J.M. Robl and J.K. Heideman, Production of Transgenic Rabbits and Rats.
L. Cioffi, J.J. Kopchik, and H.Y. Chen, Production of TransgenicPoultry and Fish.
M.J. Martin and C.A. Pinkert, Production of Transgenic Swine.
C.E. Rexroad, Jr. and H.W. Hawk, Production of Transgenic Ruminants.
- No. of pages: 364
- Language: English
- Copyright: © Academic Press 1994
- Published: January 3, 1994
- Imprint: Academic Press
- eBook ISBN: 9780323137836
About the Editor
He earned his Ph.D. from the University of Georgia and was a postdoctoral fellow at the University of Pennsylvania. For over 30 years, his research revolved around animal modeling and transgenesis. He has published extensively on transgenic modeling, reproductive biology, and embryology of laboratory and domestic animals. His laboratory developed a number of enabling technologies for the genetic engineering of both nuclear and mitochondrial genomes, as well as mitochondrial modeling strategies to address human developmental and metabolic diseases.
He served as an editor of Transgenic Research on the editorial boards of five others. His research was funded by NIH, USDA, NSF, private foundations and industry. He was a Sigma Xi national lecturer from 1993-1995 and a recipient of the 1997 Doerenkamp-Zbinden Foundation Research Prize (awarded for biomedical research that significantly impacts on the welfare and well-being of animals used in research). He was elected a fellow of the American Association for the Advancement of Science (AAAS) in 2011.
Affiliations and Expertise
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