Transfusion Medicine and Hemostasis

Transfusion Medicine and Hemostasis

Clinical and Laboratory Aspects

2nd Edition - May 13, 2013

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  • Editors: Beth H. Shaz, Christopher D. Hillyer
  • eBook ISBN: 9780123977885

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Description

The second edition of Transfusion Medicine and Hemostasis continues to be the only "pocket-size" quick reference for pathology residents and transfusion medicine fellows. It covers all topics in blood banking, transfusion medicine, and clinical and laboratory based coagulation. Short, focused chapters, organized by multiple hierarchical headings, are supplemented with up to 10 suggested reading citations. This single reference covers essentially all the topics required to meet the goals and objectives of a major program in transfusion medicine and clinical coagulation. New chapters in the coagulation testing section reflect the development of new tests available and their incorporation into clinical practice. Coverage includes essential updates on the importance of new cellular therapies, peripheral blood and bone marrow hematopoietic progenitor cells, as well as cord blood banking and regenerative medicine. The authors also examine advances in the understanding of molecular testing and pathogen reduction in two separate quality control chapters (one for blood centers and one for hospitals).

Key Features

  • Updated content covers new coagulation tests, cellular therapies, and quality control issues
  • Easy to use, with focused, well-defined chapters in a standardized format throughout
  • Offers quick "cross-reference" lists at the end of each chapter
  • Includes lists of common abbreviations and indexes that cross reference diagnostic, clinical and therapeutic commonalities

Readership

Residents and fellows in hematology, transfusion medicine, pathology, and anesthesiology; practicing physicians in hematology, transfusion medicine, pathology, and anesthesiology.

Table of Contents

  • TABLE OF CONTENTS:

    I. Blood Banking and Transfusion Medicine

    A. Introduction

    1. BLOOD BANKING AND TRANSFUSION MEDICINE – THE FIELD, THE DISCIPLINE AND THE INDUSTRY
    CHRISTOPHER D. HILLYER, MD

    2. A BRIEF HISTORY OF BLOOD TRANSFUSION
    ALFRED J. GRINDON, MD

    3. INTRODUCTION TO QUALITY SYSTEMS and QUALITY MANAGEMENT JIMMIE L. EVANS AND CHRISTOPHER D. HILLYER, MD

    B. Blood Banking

    4. THE ROLE OF THE PHYSICIAN IN THE BLOOD CENTER
    CHRISTOPHER D. HILLYER, MD

    a. Donation process

    5. BLOOD DONOR, DONATION PROCESS AND TECHNICAL ASPECTS OF BLOOD COLLECTION
    KRISTA L. HILLYER, MD

    6. APHERESIS BLOOD COMPONENT COLLECTIONS
    KRISTA L. HILLYER, MD

    7. RECIPIENT-SPECIFIC BLOOD DONATION
    KRISTA L. HILLYER, MD

    8. ADVERSE DONOR REACTIONS
    KRISTA L. HILLYER, MD

    b. Component manufacturing

    9. COMPONENT PREPARATION AND MANUFACTURING
    COURTNEY E. GREENE AND CHRISTOPHER D. HILLYER, MD

    c. Donor testing

    10. SEROLOGIC TESTING OF DONOR PRODUCTS
    KRISTA L. HILLYER, MD

    11. OVERVIEW OF INFECTIOUS DISEASE TESTING
    CHRISTOPHER D. HILLYER, MD

    12. HIV SCREENING OF DONOR PRODUCTS
    KRISTA L. HILLYER, MD

    13. HEPATITIS B SCREENING OF DONOR PRODUCT
    KRISTA L. HILLYER, MD

    14. HEPATITIS C SCREENING OF DONOR PRODUCT
    KRISTA L. HILLYER, MD

    15. WNV SCREENING OF DONOR PRODUCT
    KRISTA L. HILLYER, MD

    16. SYPHILIS, HTLV, AND CHAGAS TESTING OF DONOR PRODUCT
    CHELSEA A. SHEPPARD, MD AND KRISTA L. HILLYER, MD

    17. BACTERIAL DETECTION METHODS
    BETH H. SHAZ, MD

    C. Transfusion Medicine

    18. THE ROLE OF THE TRANSFUSION SERVICE PHYSICIAN
    BETH H. SHAZ, MD and CHRISTOPHER D. HILLYER, MD

    a. Testing

    19. PRETRANSFUSION TESTING
    BETH H. SHAZ, MD

    20. ANTIBODY IDENTIFICATION
    BETH H. SHAZ, MD

    21. DIRECT ANTIGLOBULIN TEST
    BETH H. SHAZ, MD

    b. Blood groups

    22. ABO AND H BLOOD GROUP SYSTEMS
    BETH H. SHAZ, MD

    23. RH BLOOD GROUP SYSTEM
    BETH H. SHAZ, MD

    24. KELL AND KIDD BLOOD GROUP SYSTEMS
    BETH H. SHAZ, MD

    25. MNS AND DUFFY BLOOD GROUP SYSTEMS
    BETH H. SHAZ, MD JOHN D. ROBACK, MD, PhD

    26. LEWIS,I , AND P BLOOD GROUP SYSTEMS
    BETH H. SHAZ, MD

    27. OTHER BLOOD GROUP SYSTEMS, COLLECTIONS, AND ANTIGENS
    BETH H. SHAZ, MD

    c. Blood products

    28. RED BLOOD CELLS AND RELATED PRODUCTS
    CHRISTOPHER D. HILLYER, MD

    29. PLASMA PRODUCTS
    CASSSANDRA D. JOSEPHSON, MD and CHRISTOPHER D. HILLYER, MD

    30. PLATELET PRODUCTS
    BETH H. SHAZ, MD

    31. CRYOPRECIPITATE
    BETH H. SHAZ, MD and CHRISTOPHER D. HILLYER, MD

    32. GRANULOCYTE PRODUCTS
    CHRISTOPHER D. HILLYER, MD AND LAWRENCE B. FIALCOW, DO
    33. ALBUMIN AND RELATED PRODUCTS
    ANNE M. WINKLER, MD AND BETH H. SHAZ, MD

    34. HUMAN IMMUNOGLOBULIN PREPARATIONS
    BETH H. SHAZ, MD

    35. RH IMMUNE GLOBULIN
    BETH H. SHAZ, MD

    d.Product modifications

    36. IRRADIATION OF BLOOD PRODUCTS
    BETH H. SHAZ, MD and CHRISTOPHER D. HILLYER, MD

    37. LEUKOREDUCTION OF BLOOD PRODUCTS
    JAMES C. ZIMRING, MD, PhD

    38. CMV- SAFE BLOOD PRODUCTS
    JOHN D. ROBACK, MD, PhD

    39. FROZEN BLOOD PRODUCTS
    CASSSANDRA D. JOSEPHSON, MD and BETH H. SHAZ, MD

    40. WASHED BLOOD PRODUCTS
    CASSSANDRA D. JOSEPHSON, MD and BETH H. SHAZ, MD

    41. VOLUME REDUCED BLOOD PRODUCTS
    CASSSANDRA D. JOSEPHSON, MD

    e. Specific clinical settings

    42. NEONATAL AND PEDIATRIC TRANSFUSION MEDICINE
    JEANNE E. HENDRICKSON, MD AND CASSSANDRA D. JOSEPHSON, MD

    43. PERINATAL TRANSFUSION MEDICINE
    BETH H. SHAZ, MD

    44. AUTOIMMUNE HEMOLYTIC ANEMIAS
    BETH H. SHAZ, MD and CHRISTOPHER D. HILLYER, MD

    45. TRANSFUSION MANAGEMENT IN PATIENTS WITH HEMOGLOBINOPATHIES
    BETH H. SHAZ, MD

    46. TRANSFUSION OF PATIENTS UNDERGOING HPC AND SOLID ORGAN TRANSPLANTATION
    JEANNE E. HENDRICKSON, MD AND JOHN D. ROBACK, MD, PhD

    47. TRANSFUSION OF HIV POSITIVE PATIENTS
    JEANNE E. HENDRICKSON, MD AND JOHN D. ROBACK, MD, PhD

    48. TRANSFUSION MANAGEMENT IN PATIENTS WHO REFUSE BLOOD TRANSFUSION
    JEANNE E. HENDRICKSON, MD AND JOHN D. ROBACK, MD, PhD

    49. PLATELET TRANSFUSION REFRACTORY PATIENTS
    JEANNE E. HENDRICKSON, MD and JOHN D. ROBACK, MD, PhD

    50. MASSIVE TRANSFUSION
    BETH H. SHAZ, MD and CHRISTOPHER D. HILLYER, MD

    51. PERIOPERATIVE BLOOD MANAGEMENT
    BETH H. SHAZ, MD

    f. Transfusion reactions

    52. ADVERSE EVENTS AND OUTCOMES FOLLOWING TRANSFUSION: AN OVERVIEW
    CASSSANDRA D. JOSEPHSON, MD and CHRISTOPHER D. HILLYER, MD

    53. FEBRILE NON-HEMOLYTIC TRANSFUSION REACTIONS
    CASSSANDRA D. JOSEPHSON, MD

    54. ALLERGIC, ANAPHYLACTOID AND ANAPHYLATIC REACTIONS
    BETH H. SHAZ, MD

    55. ACUTE HEMOLYTIC TRANSFUSION REACTIONS
    CASSSANDRA D. JOSEPHSON, MD and CHRISTOPHER D. HILLYER, MD

    56. DELAYED HEMOLYTIC TRANSFUSION REACTIONS
    CASSSANDRA D. JOSEPHSON, MD

    57. TRANSFUSION ASSOCIATED CIRCULATORY OVERLOAD
    JEANNE E. HENDRICKSON, MD and CHRISTOPHER D. HILLYER, MD

    58. TRANSFUSION RELATED ACUTE LUNG INJURY
    JEANNE E. HENDRICKSON, MD and CHRISTOPHER D. HILLYER, MD

    59. SEPTIC TRANSFUSION REACTIONS
    CASSSANDRA D. JOSEPHSON, MD

    60. METABOLIC, HYPOTENSIVE AND OTHER ACUTE REACTIONS AND COMPLICATIONS
    BETH H. SHAZ, MD

    61. POST TRANSFUSION PURPURA
    ALFRED J. GRINDON

    62. TRANSFUSION ASSOCIATED GRAFT VERSUS HOST DISEASE
    BETH H. SHAZ, MD and CHRISTOPHER D. HILLYER, MD

    63. MICROCHIMERISM
    BETH H. SHAZ, MD and CHRISTOPHER D. HILLYER, MD

    64. TRANSFUSION RELATED IMMUNOMODULATION
    JAMES C. ZIMRING, MD, PhD

    65. IRON OVERLOAD
    CASSSANDRA D. JOSEPHSON, MD

    66. TRANSFUSION TRANSMITTED DISEASES
    BETH H. SHAZ, MD

    g. Therapeutic apheresis and phlebotomy

    67. OVERVIEW TO THERAPEUTIC APHERESIS
    BETH H. SHAZ, MD

    68. THERAPEUTIC PLASMA EXCHANGE
    BETH H. SHAZ, MD

    69. THERAPEUTIC ERYTHROCYTAPHERESIS
    BETH H. SHAZ, MD

    70. THERAPEUTIC THROMBOCYTAPHERESIS
    BETH H. SHAZ, MD

    71. THERAPEUTIC LEUKOCYTAPHERESIS
    BETH H. SHAZ, MD

    72. EXTRACORPOREAL PHOTOPHERESIS
    MARY DORROW, MD JEANNE E. HENDRICKSON, MD, and JOHN D. ROBACK, MD, PhD

    73. LDL APHERESIS
    BETH H. SHAZ, MD

    74. IMMUNOABSORPTION
    BETH H. SHAZ, MD

    75. THERAPEUTIC PHLEBOTOMY
    LAWRENCE B. FIALCOW, DO and BETH H. SHAZ, MD

    h. Cellular therapy and tissue banking

    76. HPC PRODUCTS
    JOHN D. ROBACK, MD, PhD and ELLIE HAMILTON

    77. TISSUE BANKING in the HOSPITAL SETTING
    CASSSANDRA D. JOSEPHSON, MD

    II. Coagulation

    A. Introduction

    78. AN OVERVIEW OF THE COAGULATION SYSTEM
    THOMAS C. ABSHIRE, MD and SHAWN JOBE, MD, PhD

    B. Clinical coagulation

    79. APPROACH TO THE BLEEDING PATIENT
    THOMAS C. ABSHIRE, MD

    a. Neonatal thrombocytopenia

    80. CONGENITAL THROMBOCYTOPENIA
    SHAWN JOBE, MD, PhD

    81. NEONATAL ALLOIMMUNE THROMBOCYTOPENIA
    CAROLYN BENNETT, MD

    82. ACQUIRED NEONATAL THROMBOCYTOPENIA
    CAROLYN BENNETT, MD

    b. inherited platelet function disorders

    83. BERNARD-SOULIER SYNDROME AND OTHER GPIB-IX-V RELATED RECEPTOR DEFECTS
    SHAWN JOBE, MD, PhD

    84. GLANZMANN'S THROMBOCYTOPENIA
    SHAWN JOBE, MD, PhD

    85. PLATELET STORAGE GRANULE DEFECTS
    SHAWN JOBE, MD, PhD

    86. FAILURE TO RELEASE AND ASPIRIN-LIKE DEFECTS
    SHAWN JOBE, MD, PhD

    c. Immune thrombocytopenia

    87. ACUTE (CHILDHOOD) IMMUNE THROMBOCYTOPENIC PURPURA CAROLYN BENNETT, MD

    88. CHRONIC IMMUNE THROMBOCYTOPENIC PURPURA
    CAROLYN BENNETT, MD

    89. DRUG INDUCED THROMBOCYTOPENIA
    CAROLYN BENNETT, MD

    90. HEPARIN INDUCED THROMBOCYTOPENIA
    CHRISTINE KEMPTON, MD

    91. AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME
    MICHAEL BRIONES, DO

    d. Immune mediated coagulopathies

    92. HEMOLYTIC UREMIC SYNDROME
    MICHAEL BRIONES, DO

    93. THROMBOTIC THROMBOCYTOPENIC PURPURA
    CHRISTINE KEMPTON, MD

    94. ANTIPHOSPHOLIPID ANTIBODY SYNDROME
    MICHAEL BRIONES, DO

    e. congenital bleeding disorders

    95. VON WILLEBRAND DISEASE
    THOMAS C. ABSHIRE, MD

    96. HEMOPHILIA A
    AMY DUNN, MD

    97. HEMOPHILIA B
    AMY DUNN, MD

    98. CONGENITAL DISORDERS OF FIBRINOGEN
    SHANNON MEEKS, MD

    99. FACTOR XIII, D á2-ANTIPLASMIN, AND PLASMINOGEN ACTIVATOR INHIBITOR-1 DEFICIENCIES
    SHANNON MEEKS, MD

    100. FACTOR XI DEFICIENCY
    THOMAS C. ABSHIRE, MD

    101. FACTOR VII DEFICIENCY
    SHANNON MEEKS, MD

    102. FACTOR II, FACTOR V, AND FACTOR X DEFICIENCIES
    SHANNON MEEKS, MD

    f. acquired bleeding disorders

    103. BLEEDING DISORDERS IN PREGNANCY
    CHRISTINE KEMPTON, MD

    104. VASCULAR BLEEDING DISORDERS
    MICHAEL BRIONES, DO

    105. BLEEDING RISKS WITH LIVER DISEASE
    THOMAS C. ABSHIRE, MD

    106. BLEEDING RISKS WITH VITAMIN K DEFICIENCY
    THOMAS C. ABSHIRE, MD

    107. BLEEDING RISKS WITH CARDIAC DISEASE
    THOMAS C. ABSHIRE, MD

    108. BLEEDING RISKS WITH RENAL DISEASE
    THOMAS C. ABSHIRE, MD

    109. BLEEDING IN CANCER
    MICHAEL BRIONES, DO

    110. DISSEMINATED INTRAVASCULAR COAGULOPATHY
    AMY DUNN, MD

    111. ACQUIRED COAGULATION FACTOR INHIBITORS
    CHRISTINE KEMPTON, MD

    C. Laboratory testing of coagulation

    a. Introduction

    112. INTRODUCTION TO COAGULATION TESTING
    JAMES C. ZIMRING, MD, PhD

    b. Screening tests

    113. PROTHROMBIN TIME AND ACTIVATED PARTIAL THROMBOPLASTIN TIME
    JAMES C. ZIMRING, MD, PhD

    114. PLATELET COUNT
    JAMES C. ZIMRING, MD, PhD

    115. GLOBAL TESTS FOR PRIMARY HEMOSTASIS
    CONNIE H. MILLER Ph.D.

    c. Laboraty assessment of platelet disorders

    116. PLATELET AGGREGATION STUDIES
    CONNIE H. MILLER Ph.D.

    117. LABORATORY DIAGNOSIS OF GENETIC PLATELET FUNCTION DEFECTS
    CONNIE H. MILLER Ph.D.

    118. LABORATORY DIAGNOSIS OF ACQUIRED PLATELET FUNCTION DEFECTS
    CONNIE H. MILLER Ph.D.

    119. LABORATORY DIAGNOSIS IMMUNE THROMBOCYTOPENIC PURPURA
    CAROLYN BENNETT, MD

    120. ADAMTS 13 ASSAYS
    CHRISTINE KEMPTON, MD

    121. LABORATORY TESTING FOR HEPARIN INDUCED THROMBOCYTOPENIA
    ANNE M. WINKLER, MD AND JAMES C. ZIMRING, MD, PHD

    d. Laboratoy assessment of VWD

    122. MOLECULAR BIOLOGY OF VON WILLEBRAND DISEASE
    CONNIE H. MILLER Ph.D.

    123. DIAGNOSIS OF INHERITED VON WILLEBRAND DISEASE
    Connie H. Miller Ph.D.

    124. LABORATORY DIAGNOSIS OF ACQUIRED VWD
    CONNIE H. MILLER Ph.D.

    125. LABORATORY ASSESSMENT OF TREATMENT OF VWD
    CONNIE H. MILLER Ph.D.

    e. Laboratoy assessment of coagulation factor disorders

    126. SPECIFIC FACTOR ASSAYS
    CONNIE H. MILLER Ph.D.

    127. MIXING STUDIES
    CONNIE H. MILLER Ph.D.

    128. SPECIFIC FACTOR INHIBITORS
    Connie H. Miller Ph.D.

    f. Laboratoy assessment of fibrinogen and fibrinolysis

    129. LABORATORY DIAGNOSIS OF DYSFIBRINOGENEMIA AND AFIBRINOGENEMIA
    THOMAS C. ABSHIRE, MD

    130. LABORATORY ASSESSMENT OF FIBRINOLYSIS
    THOMAS C. ABSHIRE, MD

    g. Tests for hypercoagulable state

    131. GENERAL OVERVIEW OF THE HYPERCOAGULABLE STATE
    MICHAEL BRIONES, DO

    132. ANTITHROMBIN TESTING
    JAMES C. ZIMRING, MD, PhD

    133. PROTEINS C, S, AND Z
    JAMES C. ZIMRING, MD, PhD

    134. ACTIVATED PROTEIN C RESISTANCE AND FACTOR V LEIDEN
    ANNE M. WINKLER MD and JAMES C. ZIMRING, MD, PhD

    135. PROTHROMBIN GENE MUTATION
    ANNE M. WINKLER MD and JAMES C. ZIMRING, MD, PhD

    136. HYPERHOMOCYSTENEMIA
    JAMES C. ZIMRING, MD, PhD

    137. LUPUS ANTICOAGULANT AND ANTIPHOSPHOLIPID ANTIBODIES
    MICHAEL BRIONES, DO

    138. LIPOPROTEIN (A)
    ANNE M. WINKLER MD and JAMES C. ZIMRING, MD, PhD

    139. FACTOR LEVEL ABNORMALITIES ASSOCIATED WITH THROMBOSIS
    JAMES C. ZIMRING, MD, PhD

    h. Tests for activation of the coagulation system

    140. LABORATORY MANAGEMENT OF DIC
    THOMAS C. ABSHIRE, MD

    i. Laboratoy support for anticoagulation

    141. HEPARIN MONITORING
    ANNE WINKLER MD AND JAMES C. ZIMRING, MD, PhD

    142. WARFARIN MONITORING
    ANNE M. WINKLER M.D.

    D. Coagulation factor products

    143. PROTHROMBIN COMPLEX CONCENTRATES
    CHRISTINE KEMPTON, MD

    144. VON WILLEBRAND FACTOR PRODUCTS
    THOMAS C. ABSHIRE, MD

    145. FACTOR VIII CONCENTRATES
    AMY DUNN, MD

    146. FACTOR IX CONCENTRATES
    AMY DUNN, MD

    147. FACTOR VII CONCENTRATE
    CHRISTINE KEMPTON, MD

    148. ANTITHROMBIN PRODUCTS
    MICHAEL BRIONES, DO

    149. PROTEIN C PRODUCTS
    MICHAEL BRIONES, DO

Product details

  • No. of pages: 1014
  • Language: English
  • Copyright: © Elsevier Science 2013
  • Published: May 13, 2013
  • Imprint: Elsevier Science
  • eBook ISBN: 9780123977885

About the Editors

Beth H. Shaz

Beth H. Shaz, MD, is Chief Medical and Scientific Officer, Executive Vice President at New York Blood Center, and Adjunct Assistant Professor, Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University. Beth is responsible for all medical and scientific activities throughout the NYBC network, which includes Rhode Island Blood Center, Innovative Blood Resources (Memorial Blood Center and Nebraska Blood Center), Community Blood Center of Greater Kansas City, and Blood Bank of Delmarva. Medical activities comprise of hemophilia services, clinical apheresis services, perioperative autologous transfusion services, cellular therapy, medical education, medical consultation, transfusion services, bone marrow donor recruitment, and donor management. Scientific activities include basic science at the Lindsey F. Kimball Research Institute and Comprehensive Cell Solutions (CCS), which contains translational and clinical research. NYBC’s scientific and medical activities focus on transfusion medicine, cell therapy, regenerative medicine, infectious disease, hematology, and personalized medicine. Beth is an editor of ten books in transfusion medicine, author of over 130 articles pertaining to transfusion medicine. She is an associate editor of TRANSFUSION and on the editorial board of BLOOD. Previously, she was an Associate Professor at Emory University School of Medicine and director of the transfusion service at Grady Memorial Hospital. Also, she was an instructor at Harvard Medical School and associate director of the transfusion service at Beth Israel Deaconess Medical Center in Boston. Beth received her MD with research distinction from the University of Michigan and BS in chemical engineering with distinction from Cornell University. She completed a general surgery internship at Georgetown University, an anatomic & clinical pathology residency at Beth Israel Deaconess Medical Center, and a transfusion medicine fellowship at Harvard Medical School.

Affiliations and Expertise

Chief Medical and Scientific Officer and Executive Vice President, New York Blood Center, New York, New York, USA Adjunct Assistant Professor, Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA

Christopher D. Hillyer

Christopher D. Hillyer, MD, is President and CEO of New York Blood Center and Professor, Department of Medicine, Weill Cornell Medical College, New York, NY. Previously, he was the tenured, endowed Distinguished Service Professor, Department of Pathology and Laboratory Medicine, Emory University School of Medicine and served as director of the Emory Center for Transfusion and Cellular Therapies with responsibility for all aspects of clinical and academic transfusion medicine at Emory’s seven principle hospitals. Dr. Hillyer is an editor of twelve textbooks in transfusion medicine, author of over 160 articles pertaining to transfusion, human immunodeficiency virus, and herpes viruses, most notably cytomegalovirus. Nationally recognized as an expert in hematology and blood transfusion, Dr. Hillyer is also a past-president, board of directors of AABB and a former trustee of the National Blood Foundation. Dr. Hillyer has been awarded many million dollars in research funding from the National Institutes of Health, the Centers for Disease Control and Prevention and other agencies. He was an associate editor of Transfusion and serves on several other editorial boards. Dr. Hillyer was formally recognized for his work in Africa as part of the AABB/Emory cooperative agreement from the President’s Emergency Plan For AIDS Relief (PEPFAR), and is a recipient of two Tiffany Awards from the American Red Cross where he also served as a medical director and a member of their national Medical Advisory Board. He also received the 2014 Emily Cooley Award from AABB for his “significant commitment and contributions to the field of transfusion medicine through extensive teaching, mentoring and professional leadership, and the countless clinical, scientific and innovative resource materials he has created to educate others”. He is a co-founder of Transfusion & Transplantation Technologies, Inc (3Ti) and holds over 20 patents or patents pending. Dr. Hillyer is board certified in transfusion medicine, hematology, medical oncology and internal medicine. He received his BS from Trinity College, and his MD from the University of Rochester School of Medicine, with postgraduate training and fellowships in hematology-oncology, transfusion medicine and bone marrow transplantation at Tufts-New England Medical Center.

Affiliations and Expertise

President and Chief Executive Officer, New York Blood Center, New York, New York, USA Professor, Department of Medicine, Weill Cornell Medical College, New York, New York, USA

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  • ESPINO A. Mon May 14 2018

    Transfusion Medicine and Hemostasis

    Excelente libro; de apoyo para la academia y el trabajo diario. Con un contenido práctico tanto en hemostasia y coagulación; como en Banco de sangre.

  • EmanuelDimitrov Mon Apr 09 2018

    good book

    very good book