Transfusion Medicine and Hemostasis
Clinical and Laboratory Aspects
Free Global Shipping
No minimum orderDescription
The second edition of Transfusion Medicine and Hemostasis continues to be the only "pocket-size" quick reference for pathology residents and transfusion medicine fellows. It covers all topics in blood banking, transfusion medicine, and clinical and laboratory based coagulation. Short, focused chapters, organized by multiple hierarchical headings, are supplemented with up to 10 suggested reading citations. This single reference covers essentially all the topics required to meet the goals and objectives of a major program in transfusion medicine and clinical coagulation. New chapters in the coagulation testing section reflect the development of new tests available and their incorporation into clinical practice. Coverage includes essential updates on the importance of new cellular therapies, peripheral blood and bone marrow hematopoietic progenitor cells, as well as cord blood banking and regenerative medicine. The authors also examine advances in the understanding of molecular testing and pathogen reduction in two separate quality control chapters (one for blood centers and one for hospitals).
Key Features
- Updated content covers new coagulation tests, cellular therapies, and quality control issues
- Easy to use, with focused, well-defined chapters in a standardized format throughout
- Offers quick "cross-reference" lists at the end of each chapter
- Includes lists of common abbreviations and indexes that cross reference diagnostic, clinical and therapeutic commonalities
Readership
Residents and fellows in hematology, transfusion medicine, pathology, and anesthesiology; practicing physicians in hematology, transfusion medicine, pathology, and anesthesiology.
Table of Contents
- TABLE OF CONTENTS:
I. Blood Banking and Transfusion Medicine
A. Introduction
1. BLOOD BANKING AND TRANSFUSION MEDICINE – THE FIELD, THE DISCIPLINE AND THE INDUSTRY
CHRISTOPHER D. HILLYER, MD
2. A BRIEF HISTORY OF BLOOD TRANSFUSION
ALFRED J. GRINDON, MD
3. INTRODUCTION TO QUALITY SYSTEMS and QUALITY MANAGEMENT JIMMIE L. EVANS AND CHRISTOPHER D. HILLYER, MD
B. Blood Banking
4. THE ROLE OF THE PHYSICIAN IN THE BLOOD CENTER
CHRISTOPHER D. HILLYER, MD
a. Donation process
5. BLOOD DONOR, DONATION PROCESS AND TECHNICAL ASPECTS OF BLOOD COLLECTION
KRISTA L. HILLYER, MD
6. APHERESIS BLOOD COMPONENT COLLECTIONS
KRISTA L. HILLYER, MD
7. RECIPIENT-SPECIFIC BLOOD DONATION
KRISTA L. HILLYER, MD
8. ADVERSE DONOR REACTIONS
KRISTA L. HILLYER, MD
b. Component manufacturing
9. COMPONENT PREPARATION AND MANUFACTURING
COURTNEY E. GREENE AND CHRISTOPHER D. HILLYER, MD
c. Donor testing
10. SEROLOGIC TESTING OF DONOR PRODUCTS
KRISTA L. HILLYER, MD
11. OVERVIEW OF INFECTIOUS DISEASE TESTING
CHRISTOPHER D. HILLYER, MD
12. HIV SCREENING OF DONOR PRODUCTS
KRISTA L. HILLYER, MD
13. HEPATITIS B SCREENING OF DONOR PRODUCT
KRISTA L. HILLYER, MD
14. HEPATITIS C SCREENING OF DONOR PRODUCT
KRISTA L. HILLYER, MD
15. WNV SCREENING OF DONOR PRODUCT
KRISTA L. HILLYER, MD
16. SYPHILIS, HTLV, AND CHAGAS TESTING OF DONOR PRODUCT
CHELSEA A. SHEPPARD, MD AND KRISTA L. HILLYER, MD
17. BACTERIAL DETECTION METHODS
BETH H. SHAZ, MD
C. Transfusion Medicine
18. THE ROLE OF THE TRANSFUSION SERVICE PHYSICIAN
BETH H. SHAZ, MD and CHRISTOPHER D. HILLYER, MD
a. Testing
19. PRETRANSFUSION TESTING
BETH H. SHAZ, MD
20. ANTIBODY IDENTIFICATION
BETH H. SHAZ, MD
21. DIRECT ANTIGLOBULIN TEST
BETH H. SHAZ, MD
b. Blood groups
22. ABO AND H BLOOD GROUP SYSTEMS
BETH H. SHAZ, MD
23. RH BLOOD GROUP SYSTEM
BETH H. SHAZ, MD
24. KELL AND KIDD BLOOD GROUP SYSTEMS
BETH H. SHAZ, MD
25. MNS AND DUFFY BLOOD GROUP SYSTEMS
BETH H. SHAZ, MD JOHN D. ROBACK, MD, PhD
26. LEWIS,I , AND P BLOOD GROUP SYSTEMS
BETH H. SHAZ, MD
27. OTHER BLOOD GROUP SYSTEMS, COLLECTIONS, AND ANTIGENS
BETH H. SHAZ, MD
c. Blood products
28. RED BLOOD CELLS AND RELATED PRODUCTS
CHRISTOPHER D. HILLYER, MD
29. PLASMA PRODUCTS
CASSSANDRA D. JOSEPHSON, MD and CHRISTOPHER D. HILLYER, MD
30. PLATELET PRODUCTS
BETH H. SHAZ, MD
31. CRYOPRECIPITATE
BETH H. SHAZ, MD and CHRISTOPHER D. HILLYER, MD
32. GRANULOCYTE PRODUCTS
CHRISTOPHER D. HILLYER, MD AND LAWRENCE B. FIALCOW, DO
33. ALBUMIN AND RELATED PRODUCTS
ANNE M. WINKLER, MD AND BETH H. SHAZ, MD
34. HUMAN IMMUNOGLOBULIN PREPARATIONS
BETH H. SHAZ, MD
35. RH IMMUNE GLOBULIN
BETH H. SHAZ, MD
d.Product modifications
36. IRRADIATION OF BLOOD PRODUCTS
BETH H. SHAZ, MD and CHRISTOPHER D. HILLYER, MD
37. LEUKOREDUCTION OF BLOOD PRODUCTS
JAMES C. ZIMRING, MD, PhD
38. CMV- SAFE BLOOD PRODUCTS
JOHN D. ROBACK, MD, PhD
39. FROZEN BLOOD PRODUCTS
CASSSANDRA D. JOSEPHSON, MD and BETH H. SHAZ, MD
40. WASHED BLOOD PRODUCTS
CASSSANDRA D. JOSEPHSON, MD and BETH H. SHAZ, MD
41. VOLUME REDUCED BLOOD PRODUCTS
CASSSANDRA D. JOSEPHSON, MD
e. Specific clinical settings
42. NEONATAL AND PEDIATRIC TRANSFUSION MEDICINE
JEANNE E. HENDRICKSON, MD AND CASSSANDRA D. JOSEPHSON, MD
43. PERINATAL TRANSFUSION MEDICINE
BETH H. SHAZ, MD
44. AUTOIMMUNE HEMOLYTIC ANEMIAS
BETH H. SHAZ, MD and CHRISTOPHER D. HILLYER, MD
45. TRANSFUSION MANAGEMENT IN PATIENTS WITH HEMOGLOBINOPATHIES
BETH H. SHAZ, MD
46. TRANSFUSION OF PATIENTS UNDERGOING HPC AND SOLID ORGAN TRANSPLANTATION
JEANNE E. HENDRICKSON, MD AND JOHN D. ROBACK, MD, PhD
47. TRANSFUSION OF HIV POSITIVE PATIENTS
JEANNE E. HENDRICKSON, MD AND JOHN D. ROBACK, MD, PhD
48. TRANSFUSION MANAGEMENT IN PATIENTS WHO REFUSE BLOOD TRANSFUSION
JEANNE E. HENDRICKSON, MD AND JOHN D. ROBACK, MD, PhD
49. PLATELET TRANSFUSION REFRACTORY PATIENTS
JEANNE E. HENDRICKSON, MD and JOHN D. ROBACK, MD, PhD
50. MASSIVE TRANSFUSION
BETH H. SHAZ, MD and CHRISTOPHER D. HILLYER, MD
51. PERIOPERATIVE BLOOD MANAGEMENT
BETH H. SHAZ, MD
f. Transfusion reactions
52. ADVERSE EVENTS AND OUTCOMES FOLLOWING TRANSFUSION: AN OVERVIEW
CASSSANDRA D. JOSEPHSON, MD and CHRISTOPHER D. HILLYER, MD
53. FEBRILE NON-HEMOLYTIC TRANSFUSION REACTIONS
CASSSANDRA D. JOSEPHSON, MD
54. ALLERGIC, ANAPHYLACTOID AND ANAPHYLATIC REACTIONS
BETH H. SHAZ, MD
55. ACUTE HEMOLYTIC TRANSFUSION REACTIONS
CASSSANDRA D. JOSEPHSON, MD and CHRISTOPHER D. HILLYER, MD
56. DELAYED HEMOLYTIC TRANSFUSION REACTIONS
CASSSANDRA D. JOSEPHSON, MD
57. TRANSFUSION ASSOCIATED CIRCULATORY OVERLOAD
JEANNE E. HENDRICKSON, MD and CHRISTOPHER D. HILLYER, MD
58. TRANSFUSION RELATED ACUTE LUNG INJURY
JEANNE E. HENDRICKSON, MD and CHRISTOPHER D. HILLYER, MD
59. SEPTIC TRANSFUSION REACTIONS
CASSSANDRA D. JOSEPHSON, MD
60. METABOLIC, HYPOTENSIVE AND OTHER ACUTE REACTIONS AND COMPLICATIONS
BETH H. SHAZ, MD
61. POST TRANSFUSION PURPURA
ALFRED J. GRINDON
62. TRANSFUSION ASSOCIATED GRAFT VERSUS HOST DISEASE
BETH H. SHAZ, MD and CHRISTOPHER D. HILLYER, MD
63. MICROCHIMERISM
BETH H. SHAZ, MD and CHRISTOPHER D. HILLYER, MD
64. TRANSFUSION RELATED IMMUNOMODULATION
JAMES C. ZIMRING, MD, PhD
65. IRON OVERLOAD
CASSSANDRA D. JOSEPHSON, MD
66. TRANSFUSION TRANSMITTED DISEASES
BETH H. SHAZ, MD
g. Therapeutic apheresis and phlebotomy
67. OVERVIEW TO THERAPEUTIC APHERESIS
BETH H. SHAZ, MD
68. THERAPEUTIC PLASMA EXCHANGE
BETH H. SHAZ, MD
69. THERAPEUTIC ERYTHROCYTAPHERESIS
BETH H. SHAZ, MD
70. THERAPEUTIC THROMBOCYTAPHERESIS
BETH H. SHAZ, MD
71. THERAPEUTIC LEUKOCYTAPHERESIS
BETH H. SHAZ, MD
72. EXTRACORPOREAL PHOTOPHERESIS
MARY DORROW, MD JEANNE E. HENDRICKSON, MD, and JOHN D. ROBACK, MD, PhD
73. LDL APHERESIS
BETH H. SHAZ, MD
74. IMMUNOABSORPTION
BETH H. SHAZ, MD
75. THERAPEUTIC PHLEBOTOMY
LAWRENCE B. FIALCOW, DO and BETH H. SHAZ, MD
h. Cellular therapy and tissue banking
76. HPC PRODUCTS
JOHN D. ROBACK, MD, PhD and ELLIE HAMILTON
77. TISSUE BANKING in the HOSPITAL SETTING
CASSSANDRA D. JOSEPHSON, MD
II. Coagulation
A. Introduction
78. AN OVERVIEW OF THE COAGULATION SYSTEM
THOMAS C. ABSHIRE, MD and SHAWN JOBE, MD, PhD
B. Clinical coagulation
79. APPROACH TO THE BLEEDING PATIENT
THOMAS C. ABSHIRE, MD
a. Neonatal thrombocytopenia
80. CONGENITAL THROMBOCYTOPENIA
SHAWN JOBE, MD, PhD
81. NEONATAL ALLOIMMUNE THROMBOCYTOPENIA
CAROLYN BENNETT, MD
82. ACQUIRED NEONATAL THROMBOCYTOPENIA
CAROLYN BENNETT, MD
b. inherited platelet function disorders
83. BERNARD-SOULIER SYNDROME AND OTHER GPIB-IX-V RELATED RECEPTOR DEFECTS
SHAWN JOBE, MD, PhD
84. GLANZMANN'S THROMBOCYTOPENIA
SHAWN JOBE, MD, PhD
85. PLATELET STORAGE GRANULE DEFECTS
SHAWN JOBE, MD, PhD
86. FAILURE TO RELEASE AND ASPIRIN-LIKE DEFECTS
SHAWN JOBE, MD, PhD
c. Immune thrombocytopenia
87. ACUTE (CHILDHOOD) IMMUNE THROMBOCYTOPENIC PURPURA CAROLYN BENNETT, MD
88. CHRONIC IMMUNE THROMBOCYTOPENIC PURPURA
CAROLYN BENNETT, MD
89. DRUG INDUCED THROMBOCYTOPENIA
CAROLYN BENNETT, MD
90. HEPARIN INDUCED THROMBOCYTOPENIA
CHRISTINE KEMPTON, MD
91. AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME
MICHAEL BRIONES, DO
d. Immune mediated coagulopathies
92. HEMOLYTIC UREMIC SYNDROME
MICHAEL BRIONES, DO
93. THROMBOTIC THROMBOCYTOPENIC PURPURA
CHRISTINE KEMPTON, MD
94. ANTIPHOSPHOLIPID ANTIBODY SYNDROME
MICHAEL BRIONES, DO
e. congenital bleeding disorders
95. VON WILLEBRAND DISEASE
THOMAS C. ABSHIRE, MD
96. HEMOPHILIA A
AMY DUNN, MD
97. HEMOPHILIA B
AMY DUNN, MD
98. CONGENITAL DISORDERS OF FIBRINOGEN
SHANNON MEEKS, MD
99. FACTOR XIII, D á2-ANTIPLASMIN, AND PLASMINOGEN ACTIVATOR INHIBITOR-1 DEFICIENCIES
SHANNON MEEKS, MD
100. FACTOR XI DEFICIENCY
THOMAS C. ABSHIRE, MD
101. FACTOR VII DEFICIENCY
SHANNON MEEKS, MD
102. FACTOR II, FACTOR V, AND FACTOR X DEFICIENCIES
SHANNON MEEKS, MD
f. acquired bleeding disorders
103. BLEEDING DISORDERS IN PREGNANCY
CHRISTINE KEMPTON, MD
104. VASCULAR BLEEDING DISORDERS
MICHAEL BRIONES, DO
105. BLEEDING RISKS WITH LIVER DISEASE
THOMAS C. ABSHIRE, MD
106. BLEEDING RISKS WITH VITAMIN K DEFICIENCY
THOMAS C. ABSHIRE, MD
107. BLEEDING RISKS WITH CARDIAC DISEASE
THOMAS C. ABSHIRE, MD
108. BLEEDING RISKS WITH RENAL DISEASE
THOMAS C. ABSHIRE, MD
109. BLEEDING IN CANCER
MICHAEL BRIONES, DO
110. DISSEMINATED INTRAVASCULAR COAGULOPATHY
AMY DUNN, MD
111. ACQUIRED COAGULATION FACTOR INHIBITORS
CHRISTINE KEMPTON, MD
C. Laboratory testing of coagulation
a. Introduction
112. INTRODUCTION TO COAGULATION TESTING
JAMES C. ZIMRING, MD, PhD
b. Screening tests
113. PROTHROMBIN TIME AND ACTIVATED PARTIAL THROMBOPLASTIN TIME
JAMES C. ZIMRING, MD, PhD
114. PLATELET COUNT
JAMES C. ZIMRING, MD, PhD
115. GLOBAL TESTS FOR PRIMARY HEMOSTASIS
CONNIE H. MILLER Ph.D.
c. Laboraty assessment of platelet disorders
116. PLATELET AGGREGATION STUDIES
CONNIE H. MILLER Ph.D.
117. LABORATORY DIAGNOSIS OF GENETIC PLATELET FUNCTION DEFECTS
CONNIE H. MILLER Ph.D.
118. LABORATORY DIAGNOSIS OF ACQUIRED PLATELET FUNCTION DEFECTS
CONNIE H. MILLER Ph.D.
119. LABORATORY DIAGNOSIS IMMUNE THROMBOCYTOPENIC PURPURA
CAROLYN BENNETT, MD
120. ADAMTS 13 ASSAYS
CHRISTINE KEMPTON, MD
121. LABORATORY TESTING FOR HEPARIN INDUCED THROMBOCYTOPENIA
ANNE M. WINKLER, MD AND JAMES C. ZIMRING, MD, PHD
d. Laboratoy assessment of VWD
122. MOLECULAR BIOLOGY OF VON WILLEBRAND DISEASE
CONNIE H. MILLER Ph.D.
123. DIAGNOSIS OF INHERITED VON WILLEBRAND DISEASE
Connie H. Miller Ph.D.
124. LABORATORY DIAGNOSIS OF ACQUIRED VWD
CONNIE H. MILLER Ph.D.
125. LABORATORY ASSESSMENT OF TREATMENT OF VWD
CONNIE H. MILLER Ph.D.
e. Laboratoy assessment of coagulation factor disorders
126. SPECIFIC FACTOR ASSAYS
CONNIE H. MILLER Ph.D.
127. MIXING STUDIES
CONNIE H. MILLER Ph.D.
128. SPECIFIC FACTOR INHIBITORS
Connie H. Miller Ph.D.
f. Laboratoy assessment of fibrinogen and fibrinolysis
129. LABORATORY DIAGNOSIS OF DYSFIBRINOGENEMIA AND AFIBRINOGENEMIA
THOMAS C. ABSHIRE, MD
130. LABORATORY ASSESSMENT OF FIBRINOLYSIS
THOMAS C. ABSHIRE, MD
g. Tests for hypercoagulable state
131. GENERAL OVERVIEW OF THE HYPERCOAGULABLE STATE
MICHAEL BRIONES, DO
132. ANTITHROMBIN TESTING
JAMES C. ZIMRING, MD, PhD
133. PROTEINS C, S, AND Z
JAMES C. ZIMRING, MD, PhD
134. ACTIVATED PROTEIN C RESISTANCE AND FACTOR V LEIDEN
ANNE M. WINKLER MD and JAMES C. ZIMRING, MD, PhD
135. PROTHROMBIN GENE MUTATION
ANNE M. WINKLER MD and JAMES C. ZIMRING, MD, PhD
136. HYPERHOMOCYSTENEMIA
JAMES C. ZIMRING, MD, PhD
137. LUPUS ANTICOAGULANT AND ANTIPHOSPHOLIPID ANTIBODIES
MICHAEL BRIONES, DO
138. LIPOPROTEIN (A)
ANNE M. WINKLER MD and JAMES C. ZIMRING, MD, PhD
139. FACTOR LEVEL ABNORMALITIES ASSOCIATED WITH THROMBOSIS
JAMES C. ZIMRING, MD, PhD
h. Tests for activation of the coagulation system
140. LABORATORY MANAGEMENT OF DIC
THOMAS C. ABSHIRE, MD
i. Laboratoy support for anticoagulation
141. HEPARIN MONITORING
ANNE WINKLER MD AND JAMES C. ZIMRING, MD, PhD
142. WARFARIN MONITORING
ANNE M. WINKLER M.D.
D. Coagulation factor products
143. PROTHROMBIN COMPLEX CONCENTRATES
CHRISTINE KEMPTON, MD
144. VON WILLEBRAND FACTOR PRODUCTS
THOMAS C. ABSHIRE, MD
145. FACTOR VIII CONCENTRATES
AMY DUNN, MD
146. FACTOR IX CONCENTRATES
AMY DUNN, MD
147. FACTOR VII CONCENTRATE
CHRISTINE KEMPTON, MD
148. ANTITHROMBIN PRODUCTS
MICHAEL BRIONES, DO
149. PROTEIN C PRODUCTS
MICHAEL BRIONES, DO
Product details
- No. of pages: 1014
- Language: English
- Copyright: © Elsevier Science 2013
- Published: May 13, 2013
- Imprint: Elsevier Science
- eBook ISBN: 9780123977885
About the Editors
Beth H. Shaz
Beth H. Shaz, MD, is Chief Medical and Scientific Officer, Executive Vice President at New York Blood Center, and Adjunct Assistant Professor, Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University. Beth is responsible for all medical and scientific activities throughout the NYBC network, which includes Rhode Island Blood Center, Innovative Blood Resources (Memorial Blood Center and Nebraska Blood Center), Community Blood Center of Greater Kansas City, and Blood Bank of Delmarva. Medical activities comprise of hemophilia services, clinical apheresis services, perioperative autologous transfusion services, cellular therapy, medical education, medical consultation, transfusion services, bone marrow donor recruitment, and donor management. Scientific activities include basic science at the Lindsey F. Kimball Research Institute and Comprehensive Cell Solutions (CCS), which contains translational and clinical research. NYBC’s scientific and medical activities focus on transfusion medicine, cell therapy, regenerative medicine, infectious disease, hematology, and personalized medicine. Beth is an editor of ten books in transfusion medicine, author of over 130 articles pertaining to transfusion medicine. She is an associate editor of TRANSFUSION and on the editorial board of BLOOD. Previously, she was an Associate Professor at Emory University School of Medicine and director of the transfusion service at Grady Memorial Hospital. Also, she was an instructor at Harvard Medical School and associate director of the transfusion service at Beth Israel Deaconess Medical Center in Boston. Beth received her MD with research distinction from the University of Michigan and BS in chemical engineering with distinction from Cornell University. She completed a general surgery internship at Georgetown University, an anatomic & clinical pathology residency at Beth Israel Deaconess Medical Center, and a transfusion medicine fellowship at Harvard Medical School.
Affiliations and Expertise
Chief Medical and Scientific Officer and Executive Vice President, New York Blood Center, New York, New York, USA
Adjunct Assistant Professor, Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA
Christopher D. Hillyer
Christopher D. Hillyer, MD, is President and CEO of New York Blood Center and Professor, Department of Medicine, Weill Cornell Medical College, New York, NY. Previously, he was the tenured, endowed Distinguished Service Professor, Department of Pathology and Laboratory Medicine, Emory University School of Medicine and served as director of the Emory Center for Transfusion and Cellular Therapies with responsibility for all aspects of clinical and academic transfusion medicine at Emory’s seven principle hospitals. Dr. Hillyer is an editor of twelve textbooks in transfusion medicine, author of over 160 articles pertaining to transfusion, human immunodeficiency virus, and herpes viruses, most notably cytomegalovirus. Nationally recognized as an expert in hematology and blood transfusion, Dr. Hillyer is also a past-president, board of directors of AABB and a former trustee of the National Blood Foundation. Dr. Hillyer has been awarded many million dollars in research funding from the National Institutes of Health, the Centers for Disease Control and Prevention and other agencies. He was an associate editor of Transfusion and serves on several other editorial boards. Dr. Hillyer was formally recognized for his work in Africa as part of the AABB/Emory cooperative agreement from the President’s Emergency Plan For AIDS Relief (PEPFAR), and is a recipient of two Tiffany Awards from the American Red Cross where he also served as a medical director and a member of their national Medical Advisory Board. He also received the 2014 Emily Cooley Award from AABB for his “significant commitment and contributions to the field of transfusion medicine through extensive teaching, mentoring and professional leadership, and the countless clinical, scientific and innovative resource materials he has created to educate others”. He is a co-founder of Transfusion & Transplantation Technologies, Inc (3Ti) and holds over 20 patents or patents pending. Dr. Hillyer is board certified in transfusion medicine, hematology, medical oncology and internal medicine. He received his BS from Trinity College, and his MD from the University of Rochester School of Medicine, with postgraduate training and fellowships in hematology-oncology, transfusion medicine and bone marrow transplantation at Tufts-New England Medical Center.
Affiliations and Expertise
President and Chief Executive Officer, New York Blood Center, New York, New York, USA
Professor, Department of Medicine, Weill Cornell Medical College, New York, New York, USA
Ratings and Reviews
Latest reviews
(Total rating for all reviews)
ESPINO A. Mon May 14 2018
Transfusion Medicine and Hemostasis
Excelente libro; de apoyo para la academia y el trabajo diario. Con un contenido práctico tanto en hemostasia y coagulación; como en Banco de sangre.
EmanuelDimitrov Mon Apr 09 2018
good book
very good book