Transduction Mechanisms in Cellular Signaling

1st Edition

Cell Signaling Collection

Authors:

  • Edward A. Dennis
  • Ralph Bradshaw
  • Transduction Mechanisms in Cellular Signaling

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    Description

    Cytosol, the liquid found inside cells, is the site for multiple cell processes, including signaling from the cell membrane to sites within the cell. Cytosolic signaling mechanisms are researched and studied in graduate programs in cell biology, molecular biology, biochemistry, pharmacology, molecular and cellular physiology, pharmacy, and biomedical sciences.

    Key Features

    • Articles written and edited by experts in the field
    • Thematic volume covering material needed for young professionals joining the field of research and graduate students taking survey courses
    • Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease

    Readership

    Researchers and graduate students in Cell Biology, Molecular Biology, Biochemistry, Pharmacology, Molecular and Cellular Physiology, Pharmacy, and Biomedical Sciences.

    Details

    No. of pages:
    610
    Language:
    English
    Copyright:
    © 2011
    Published:
    Imprint:
    Academic Press
    Print ISBN:
    9780123838629
    Electronic ISBN:
    9780123838636

    About the authors

    Edward A. Dennis

    Edward A. Dennis is Distinguished Professor and former Chair of the Department of Chemistry and Biochemistry and Professor in the Department of Pharmacology in the School of Medicine at the University of California, San Diego. He is also Editor-in-Chief of the Journal of Lipid Research.

    Affiliations and Expertise

    Department of Chemistry and Biochemistry and Department of Pharmacology in the School of Medicine at the University of California, San Diego

    Ralph Bradshaw

    Ralph A. Bradshaw is Professor Emeritus in the Department of Physiology and biophysics at the University of California, Irvine. Prior to that he was on the faculty of the Department of Biological Chemistry, Washington University School of Medicine in St. Louis, MO and was Professor and Chair of the Department of Biological Chemistry at the University of California, Irvine. From 2006 to 2015, he was a member of the Mass Spectrometry Facility and Professor of Pharmaceutical Chemistry at the University of California, San Francisco. He holds degrees from Colby College and Duke University and was a post-doctoral fellow at Indiana University and the University of Washington. He has served as president for FASEB, was the founding president of the Protein Society and was the treasurer of the American Society for Biochemistry and Molecular Biology. His research has focused on protein chemistry and proteomics, with emphasis on the structure and function of growth factors and their receptors, particularly nerve growth factor and fibroblast growth factor, and the involvement of receptor tyrosine kinases in cell signalling. He has also studied in the role of proteolytic processing and N-terminal modification in protein stability and turnover.

    Affiliations and Expertise

    Department of Chemistry and Pharmaceutical Chemistry; and Mass Spectrometry Facility, University of California, San Francisco, Department of Physiology and Biophysics, College of Medicine, University of California, Irvine, Irvine, CA