Toxicology

Toxicology

First published on September 3, 1999

Write a review

  • Editors: Hans Marquardt, Siegfried Schäfer, Roger O. McClellan, Frank Welsch
  • eBook ISBN: 9780080543116

Purchase options

Purchase options
DRM-free (PDF)
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order

Description

Toxicology is a comprehensive text for researchers and graduate students in toxicology and public health. It addresses every aspect of the field, starting with the fundamentals and incorporating such areas as organ toxicology, applications, and environmental toxicology. In addition to covering the traditional subject matter of toxicology, special emphasis has been placed on recent areas of interest, such as risk assessment, apoptosis, and methodical developments.

Key Features

@introbul:Key Features
@bul:* Comprehensive text, covering all aspects of the field of toxicology
* Analyzes the importance of toxicokinetics and metabolism as well as cellular targets for the mechanisms of toxic effects
* Identifies the various classes of chemical compounds responsible for the toxic effects
* Describes the approaches and methods used by various disciplines which investigate toxic effects and their prevention
* Adapted from a very successful German text, this edition is completely revised and expanded
* The text is well illustrated with diagrams, charts, and tables

Readership

Graduate students in toxicology, pharmacology, and public health; researchers; libraries.

Table of Contents

  • H. Marquardt and S. Schäfer, Foreword. Fundamentals:
    D. Milles, History of Toxicology.
    L. Hothorn and G. Hajian, Biostatistics in Toxicology.
    B. Fichtl, Toxicokinetics.
    F. Oesch and M. Arand, Xenobiotic Metabolism.
    M. Younes, Free Radicals and Reactive Oxygen Species.
    D. Brusick, Genetic Toxicology.
    H. Marquardt, Chemical Carcinogenesis.
    R. Schulte-Hermann, B. Marian, and W. Bursch, Tumor Promotion.
    K. Tindall and R. Tennant, Transgenic Rodent Models.
    J.-A. Gustafsson and C. Corton, Receptor Biology and Pathobiology.
    D. Polka, Mechanisms of Toxicity: Programmed Cell Death (Apoptosis).
    J.P. Groton, P.J. van Bladeren, F.R. Cassee, C. De Rosa, and V. Feron, Mixtures.
    Organtoxicity:
    R. Kahl, The Liver.
    C. Cojocel and E. Lock, The Kidney.
    H. Muhle and R. McClellan, Respiratory Tract.
    P. Eyer and R. Klimmek, Blood and Blood Forming Organs.
    D. Neubert, Immune System.
    J. Riviere and N. Montiero-Riviere, Skin Toxicology.
    R. Pfeiffer, Eye.
    D. Ray and K. Andreas, Nervous System.
    D. Neubert and F. Welsch, Reproduction and Development.
    J. Thomas and M. Thomas, Endocrine System-Adrenal Cortex Thyroid and Pancreas.
    K. Schümann, B. Elsenhans, and E. Richter, Gastrointestinal Tract.
    P. Boor, Cardiovascular Toxicology.
    Toxicology of Compounds:
    G. Koss and I. Tesseraux, Hydrocarbons.
    H. Bolt and J. Borlak, Halogenated Hydrocarbons.
    S. Magda, Flurohydrocarbons.
    E. Rose, E. Hodgson, and M. Roe, Pesticides.
    G. Koss and D. Wolfe, Dioxin and Dioxin-like Polychlorinated Hydrocarbons and Biphenyls.
    E. Richter and G. Sabbioni, Aromatic Amines, Nitroarenes and Heterocyclic Aromatic Amines.
    W. Köhl and G. Eisenbrand, N-Nitroso Compounds.
    S. Schäferwq, B. Elsenhans, R.L.F. Dawes, K. Schumann, and W. Forth, Metals.
    P. Eyer, Gases.
    D. Warheit, T. Hesterberg, and G. Hart, Fiber Toxicology.
    L. Szinicz and S. Baskin, Chemical and Biological Agents.
    D. Hoffmann and E. Wynder, Active and Passive Smoking.
    J. Corbett, W. Dressler, and R. Sharma, Cosmetics.
    E. Löser and G. Stropp, Polymers.
    U. Hagen, R.J. Preston, R. Fry, and J. Kummermehr, Radiation.
    J. Westendorf, The Toxicology of Natural Compounds.
    H. Bigalke and H. Wellhoner, Bacterial Toxins.
    Application of Toxicology:
    H.W. Rüdiger, Biomonitoring and Occupational Medicine.
    Environmental Toxicology:
    R. Bull, Water.
    D.J. Paustenbach and T. Rodrigues, The Role of Toxicology and Risk Assessment in Environmental Remediation.
    Krekeler, Ecotoxicology.
    Hattan and A. Rulis, Food Toxicology.
    Gelbke, B. Hildebrand, and E. Kerfoot, Toxicological Evaluation Methods for the Registration of Chemicals.
    H. Spielmann, Alternatives in Toxicological Testing.
    A. Somogyi, Regulatory Toxicology.
    Risk Assessment:
    D. Neubert and R. Conolly, Possibilities and Methods of Quantitative Risk Assessment.
    S. Safe, Toxicity Equivalents and Their Use in Hazard and Risk Assessment.
    Appendix:
    I. Ollroge, Threshold Values and Recommendations.
    H. Marquardt and S. Schäfer, Addresses of Toxicology Center and Information Sources.

Product details

  • No. of pages: 1360
  • Language: English
  • Copyright: © Academic Press 1999
  • Published: September 3, 1999
  • Imprint: Academic Press
  • eBook ISBN: 9780080543116

About the Editors

Hans Marquardt

Dr. Seigfried Schäfer and Dr. Hans. Marquardt are the editors of the very successful German edition of Toxicology.

Affiliations and Expertise

Hamburg University Medical School and Department of Toxicology and Environmental Medicine of the Fraunhofer Society, Hamburg, Germany

Siegfried Schäfer

Dr. Seigfried Schäfer and Dr. Hans Marquardt are the editors of the very successful German edition of Toxicology.

Affiliations and Expertise

Solvay Parma Deutschland, Hannover, Germany

Roger O. McClellan

Dr. Roger O. McClennan is president and CEO of the very highly regarded and respected non-profit Chemical Industry Institute of Toxicology. CIIT conducts research directed toward reducing the uncertainties in assessing human health risks of exposures to chemicals.

Affiliations and Expertise

Chemical Industry Institute of Toxicology (CIIT), Research Triangle Park, North Carolina, U.S.A.

Frank Welsch

Frank Welsch is a senior scientist at the very highly regarded and respected non-profit Chemical Industry Institute of Toxicology. CIIT conducts research directed toward reducing the uncertainties in assessing human health risks of exposures to chemicals.

Affiliations and Expertise

Chemical Industry Institute of Toxicology (CIIT), Research Traingle Park, North Carolina, U.S.A...

Ratings and Reviews

Write a review

There are currently no reviews for "Toxicology"