Toxicology of Halogenated Hydrocarbons

Health and Ecological Effects

1st Edition - January 1, 1981
Editors: M.A.Q. Khan, R.H. Stanton
Language: English
eBook ISBN:
9 7 8 - 1 - 4 8 3 1 - 8 2 3 3 - 9

Toxicology of Halogenated Hydrocarbons: Health and Ecological Effects covers the papers of a symposium held at the 2nd Chemical Congress of the North American Continent and the… Read more

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Toxicology of Halogenated Hydrocarbons: Health and Ecological Effects covers the papers of a symposium held at the 2nd Chemical Congress of the North American Continent and the 180th national meeting of the American Chemical Society in fall of 1980 in Las Vegas, Nevada, USA. The book contains papers on human exposure and health effects; hepatotoxicity and carcinogenicity; and cytotoxicity, teratogenicity, mutagenicity, and neurotoxicity. The text also presents papers on the metabolism and toxicodynamics of halogenated hydrocarbons, as well as the embryotoxicity and environmental fate related to halogenated hydrocarbons in animals and humans.

List of Participants

Preface

Section I Human Exposure and Health Effects

Halogenated Substances: Environmental and Industrial Materials.

Chronic Toxicity of Halogenated Biphenyls and Related Compounds in Animals and Health Effects in Humans.

Trends of Organochlorine Pesticide Residues in Human Tissue.

Epidemiology of Chlorinated Hydrocarbon Insecticides.

Health Status of Factory Workers with Long-Term Exposure to Chlorinated Hydrocarbons.

Section II Hepatotoxicity and Carcinogenicity

Toxicology of Polybrominated Biphenyls.

Polybrominated Biphenyls, Polychlorinated Naphthalenes and Polychlorinated Terphenyls as Microsomal Enzyme Inducers.

PCBs as Microsomal Enzyme Inducers: Structure-Activity Rules.

Biochemical and Ultrastructural Alteration of Rat Liver by Photoheptachlor.

Retrodifferentiation: A Mechanism for the Depression of Ouabain Biliary Excretion in Male Rats Treated with 2,3,7,8-Tetrachlorodibenzo-p-dioxin.

Mammalian Toxicology of 3,3',4,4'-Tetrachloroazobenzene and 3,3',4,4'-Tetrachloroazoxybenzene: Implications in Environmental and Occupational Health.

An Epigenetic Mechanism of Carcinogenicity of Organochlorine Pesticides.

Section III Cytotoxicity, Teratogenicity, Mutagencity, and Neurotoxicity

In vitro Measurement of Polychlorinated Biphenyl Toxicity.

2,3,7,8-Tetrachlorodibenzo-p-dioxin: Toxicity in vivo and in vitro.

Cardiovascular Teratogenesis in Chick Embryos Treated with 2,3,7,8-Tetrachlorodibenzo-p-dioxin.

Water Chlorination As a Source of Aquatic Environmental Mutagens.

Mode of Action of Chlorinated Hydrocarbon Pesticides on the Nervous System.

Neurological Effects of Chlorinated Hydrocarbons.

Section IV Metabolism and Toxicodynamics

The In Vivo and In Vitro Metabolism of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in the Golden Syrian Hamster.

Biotransformations of Cyclodienes and Their Photoisomers and Hexachlorocyclopentadiene in Mammals and Fish.

Disposition of Persistent Halogenated Hydrocarbons in Higher Animals.

Disposition of Hexachlorobenzene in Domestic Animals.

Metabolism and Bilary Excretion of Chlordecone (Kepone) in Humans.

Section V Toxicity, Embryotoxicity, and Environmental Fate

Biological Effects of PCBs and PBBs on Mink and Ferrets - A Review.

Fate of Hexachlorocyclopentadiene in the Environment.

Sediment Sorption and Toxicity of Organochlorine Pesticides to Marine Invertebrates.

Nonpoint Source Pollution From PCBsr Bioavailability and Inactivation with Activated Carbon.

Index