Toxicology Handbook  - 2nd Edition - ISBN: 9780729579391

Toxicology Handbook

2nd Edition

Authors: Lindsay Murray Lindsay Murray Mark Little Ovidiu Pascu Kerry Anne Hoggett
eBook ISBN: 9780729579391
Imprint: Churchill Livingstone Australia
Published Date: 15th December 2010

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An updated guide to the approach, assessment and management of poisoned patients

Poisoning is a common emergency department presentation, and is the third major cause of hospital admission in Australia.

The new edition of this all-encompassing toxicology reference describes the risk assessment-based approach pioneered by its principal authors.

The Toxicology Handbook is written for hospital-based doctors at all levels and is divided into six sections, including an approach to the poisoned patient, specific toxins, antidotes, toxinology and antivenom.

It also deals with specific toxicology considerations like alcohol abuse, dependence and withdrawal, and poisoning in children and the elderly. Important locally relevant information on bites, stings and envenoming is also included.

The concise layout of this didactic medical guide enables readers to quickly locate required information – essential in a poisoning emergency.

Established as a primary reference in Australian Poisons Information Centres, the Toxicology Handbook is useful for doctors, nurses, ambulance service paramedics and pharmacists alike.

Table of Contents

Section 1: Introduction

  • Who are the authors
  • Scope of the book
    • Handbook of acute management of common poisonings.
    • Hands on and practical approach.
    • Rationale for drugs included

  • How to use the book
  • Universal disclaimer

Clinical: Approach to the poisoned patient

  • Overview of approach to toxicology/toxinology
  • Principles of risk assessment-based approach
  • Resuscitation, Risk assessment, Supportive care, Decontamination, Investigations, Enhanced elimination, Antidotes, Disposition

Section 2: Approach to specialist toxicology problems

  • Approach to special problems: Approach to snakebite, mushroom poisoning, plant poisoning
  • Toxidromes: Serotonin syndrome, Neuroleptic Malignant Syndrome, anticholinergic syndrome, cholinergic syndrome
  • Important poisoning manifestations and management: Seizures, coma, hypotension, delirium and agitation
  • Drugs of abuse and withdrawal syndromes: Alcohol, amphetamines, opiods, sedative hypnotics, body packers and stuffers
  • Investigations: Laboratory results: acidosis, anion gap and osmolar gap, recommended baseline investigations with interpretation. Unit conversion table: ECG interpretation in poisoning: Radiology.
  • Special populations: Paediatric poisoning: 1 tablet can kill (list), special precautions in management (overnight stay, paracetamol, risk of charcoal etc); Pregnancy and lactation and poisoning; and Geriatric poisoning

Section 3: Toxic Drugs (78 chapters)

  • Approach to diagnosis


© Churchill Livingstone Australia 2011
Churchill Livingstone Australia
eBook ISBN:

About the Author

Lindsay Murray

Affiliations and Expertise

Consultant Emergency Physician, Lismore Base Hospital, Lismore, NSW, Australia

Lindsay Murray

Affiliations and Expertise

Consultant Emergency Physician, Lismore Base Hospital, Lismore, NSW, Australia

Mark Little

Affiliations and Expertise

Consultant Emergency Physician and Clinical Toxicologist Cairns Hospital, Associate Professor School of Public Health and Tropical Medicine, Queensland Tropical Health Alliance and Consultant Clinical Toxicologist to the NSW Poisons Information Centre, Australia

Ovidiu Pascu

Affiliations and Expertise

Consultant Emergency Physician and Clinical Toxicologist, Sir Charles Gairdner Hospital, Perth, WA Poisons Information Centre; Clinical Senior Lecturer in Emergency Medicine, University of Western Australia, WA, Australia

Kerry Anne Hoggett

Affiliations and Expertise

Consultant Emergency Physician and Clinical Toxicologist, Royal Perth Hospital; VMO Clinical Toxicologist, NSW and WA Poisons Information Centres; Clinical Senior Lecturer, University of Western Australia; Adjunct Clinical Lecturer, University of Notre Dame, WA, Australia