Toxicology Cases for the Clinical and Forensic Laboratory

Toxicology Cases for the Clinical and Forensic Laboratory

1st Edition - June 20, 2020

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  • Editors: Hema Ketha, Uttam Garg
  • eBook ISBN: 9780128163733
  • Paperback ISBN: 9780128158463

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Description

Toxicology Cases for the Clinical and Forensic Laboratory brings together carefully selected case studies to teach important principles relating to drug and toxin exposures. Each case study includes contemporary clinical and forensic toxicologist studies that include a comprehensive analytical and clinical approach to patient management and address overdoses from designer drugs, to NSAIDS, to opioids, to stimulants. These cases present a comprehensive, analytical and clinical approach to managing a drug overdose. This is a must-have reference for clinical and forensic laboratory scientists, along with toxicology and pathology residents who need to know aspects of both.

Key Features

  • Brings together expert cases encompassing analytical toxicology, clinical medicine and basic science in a consolidated format
  • Presents unique and challenging cases in clinical laboratories contributed by experts in the field
  • Consolidated format that make concepts in toxicology easy to learn and teach
  • Key learning points highlighted with multiple choice questions

Readership

Residents and fellows in pathology and clinical chemistry, practicing pathologists and clinical chemists, clinical toxicologists, clinical laboratory scientists working in clinical and forensic toxicology laboratories

Table of Contents

  • SECTION I - Basic Principles
    1. An Introduction to Clinical and Forensic Toxicology
    2. Pharmacokinetics and Pharmacodynamics
    3. Laboratory Methods in Toxicology
    4. Management of an Overdose Patient
    5. Alcohols: Volatiles and Glycols

    SECTION II – Overview and Case Studies
    6. Analgesics and Anti-inflammatory Drugs
    7. Antibiotics
    8. Antidepressants and Antipsychotics
    9. Anticonvulsants
    10. Antineoplastic Drugs
    11. Cannabinoids
    12. Cardiotoxicity
    13. CNS Depressants: Benzodiazepines and Barbiturates
    14. CNS Stimulants
    15. Designer Drugs
    16. Hallucinogens and Psychedelics
    17. Immunosuppressive Drugs
    18. Opioids
    19. Toxic Herbals and Plants in U.S. 
    20. Toxic Gases
    21. Toxic Metals 
    22. Venoms and Pesticides
    23. Case Studies on Other Drugs

Product details

  • No. of pages: 540
  • Language: English
  • Copyright: © Academic Press 2020
  • Published: June 20, 2020
  • Imprint: Academic Press
  • eBook ISBN: 9780128163733
  • Paperback ISBN: 9780128158463

About the Editors

Hema Ketha

Dr. Hema Ketha completed her post-doctoral research training at the Mayo Clinic in Rochester, MN focusing on areas exploring the role of vitamin D physiology in bone and kidney diseases, protein purification and protein interactions, mouse model studies of bone disease and development, validation and clinical implementation of liquid chromatography with tandem mass spectrometry (LC-MS/MS) analytical methods for vitamin D metabolic profiling. Then she pursued post-doctoral clinical training in clinical chemistry at the Mayo Clinic before joining the Department of Pathology at the University of Michigan. She is currently a Technical Director, Toxicology and Mass Spectrometry, LabCorp, Burlington, NC. Her research interests are in clinical endocrinology, toxicology and clinical LC-MS/MS. She has won several awards from professional organizations including the AACC and ACLPS for her work in the areas of clinical chemistry and clinical mass spectrometry. She has research interests in areas of clinical endocrinology, toxicology and clinical LC-MS/MS. Additionally, she works on evaluating various immunoassays for current send-out esoteric analytes that can be validated and implemented at Michigan’s clinical laboratory. She has authored peer-reviewed publications and won several awards from professional organizations including the AACC and ACLPS for her work in the areas of clinical chemistry and clinical mass spectrometry.

Affiliations and Expertise

PhD, NRCC, Technical Director, Toxicology and Mass Spectrometry, LabCorp, Burlington, NC

Uttam Garg

Dr. Uttam Garg has published over 150 research papers, review articles, and book chapters in the area of clinical biochemistry, therapeutic drug monitoring and toxicology, and Co-Edited a book on Clinical Applications of Mass Spectrometry. His research interests include methods development in clinical laboratory diagnosis. His research interests include clinical method development on a variety of diagnostic platforms including mass spectrometry. He received his Ph.D. in Experimental Medicine from the Postgraduate Institute of Medical Education and Research in India. He received his postdoctoral training in Pharmacology at and Clinical Chemistry at New York Medical College and University of Minnesota Medical School respectively. Before joining his current position, he served as faculty at the NYU Medical Center and the University of Minnesota Medical School.

Affiliations and Expertise

Garg Department of Pathology and Laboratory Medicine, Children’s Mercy Hospital, Kansas City, MO, United States; University of Missouri School of Medicine, Kansas City, MO, United States

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  • Sophie Thu Jul 01 2021

    Interesting cases

    Interesting cases, well organized book