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Toxicology Cases for the Clinical and Forensic Laboratory brings together carefully selected case studies to teach important principles relating to drug and toxin exposures. Each case study includes contemporary clinical and forensic toxicologist studies that include a comprehensive analytical and clinical approach to patient management and address overdoses from designer drugs, to NSAIDS, to opioids, to stimulants. These cases present a comprehensive, analytical and clinical approach to managing a drug overdose. This is a must-have reference for clinical and forensic laboratory scientists, along with toxicology and pathology residents who need to know aspects of both.
- Brings together expert cases encompassing analytical toxicology, clinical medicine and basic science in a consolidated format
- Presents unique and challenging cases in clinical laboratories contributed by experts in the field
- Consolidated format that make concepts in toxicology easy to learn and teach
- Key learning points highlighted with multiple choice questions
Residents and fellows in pathology and clinical chemistry, practicing pathologists and clinical chemists, clinical toxicologists, clinical laboratory scientists working in clinical and forensic toxicology laboratories
SECTION I - Basic Principles
1. An Introduction to Clinical and Forensic Toxicology
2. Pharmacokinetics and Pharmacodynamics
3. Laboratory Methods in Toxicology
4. Management of an Overdose Patient
5. Alcohols: Volatiles and Glycols
SECTION II – Overview and Case Studies
6. Analgesics and Anti-inflammatory Drugs
8. Antidepressants and Antipsychotics
10. Antineoplastic Drugs
13. CNS Depressants: Benzodiazepines and Barbiturates
14. CNS Stimulants
15. Designer Drugs
16. Hallucinogens and Psychedelics
17. Immunosuppressive Drugs
19. Toxic Herbals and Plants in U.S.
20. Toxic Gases
21. Toxic Metals
22. Venoms and Pesticides
23. Case Studies on Other Drugs
- No. of pages:
- © Academic Press 2020
- 25th April 2020
- Academic Press
- Paperback ISBN:
Dr. Hema Ketha completed her post-doctoral research training at the Mayo Clinic in Rochester, MN focusing on areas exploring the role of vitamin D physiology in bone and kidney diseases, protein purification and protein interactions, mouse model studies of bone disease and development, validation and clinical implementation of liquid chromatography with tandem mass spectrometry (LC-MS/MS) analytical methods for vitamin D metabolic profiling. Then she pursued post-doctoral clinical training in clinical chemistry at the Mayo Clinic before joining the Department of Pathology at the University of Michigan. She is currently a Technical Director, Toxicology and Mass Spectrometry, LabCorp, Burlington, NC. Her research interests are in clinical endocrinology, toxicology and clinical LC-MS/MS. She has won several awards from professional organizations including the AACC and ACLPS for her work in the areas of clinical chemistry and clinical mass spectrometry. She has research interests in areas of clinical endocrinology, toxicology and clinical LC-MS/MS. Additionally, she works on evaluating various immunoassays for current send-out esoteric analytes that can be validated and implemented at Michigan’s clinical laboratory. She has authored peer-reviewed publications and won several awards from professional organizations including the AACC and ACLPS for her work in the areas of clinical chemistry and clinical mass spectrometry.
Hema Ketha, PhD, NRCC, FAACC Technical Director, Toxicology and Mass Spectrometry, LabCorp, Burlington, NC
Dr. Uttam Garg has published over 150 research papers, review articles, and book chapters in the area of clinical biochemistry, therapeutic drug monitoring and toxicology, and Co-Edited a book on Clinical Applications of Mass Spectrometry. His research interests include methods development in clinical laboratory diagnosis. His research interests include clinical method development on a variety of diagnostic platforms including mass spectrometry. He received his Ph.D. in Experimental Medicine from the Postgraduate Institute of Medical Education and Research in India. He received his postdoctoral training in Pharmacology at and Clinical Chemistry at New York Medical College and University of Minnesota Medical School respectively. Before joining his current position, he served as faculty at the NYU Medical Center and the University of Minnesota Medical School.
Director of Clinical Chemistry Laboratories, Children’s Mercy Hospitals and Clinics; Professor of Pediatrics Pathology, University of Missouri School of Medicine, Kansas City, MO, USA