Environmental toxicology is generally held to be the study of the potential of constituents of outdoor environments to impact either human health or the biological structure of the ecosystems involved. This volume is a first attempt to integrate toxicological studies of all of the many human environments, both indoor and outdoor, and their complex interrelationships. Included are considerations of natural environments, the agroecosystem, occupational, urban and domestic environments as well as the environment associated with Superfund sites and military deployments.

The primary emphasis is on public health, including the potential health effects of toxicants found in different environments, the bioprocessing of such toxicants in humans and surrogate animals and the principles of risk analysis.

Key Features

  • Approaches the toxicology of human environments in a new and unique way, stressing the complex interrelationships of all human environments and the implication for human and environmental health
  • Each chapter is written by an acknowledged expert and is addressed to those interested in the broader implications of the environmental modifications that are always associated with the activities of humans living and working in them


Scientists and researchers interested in molecular biology, translational science, and toxicology

Table of Contents

  1. Human Environments: Definition, Scope and the Role of Toxicology
  2. Ernest Hodgson

  3. Estimating Human Exposure: Improving Accuracy with Chemical Markers
  4. Roger C. Cochran and Jeffrey H. Driver

  5. Metabolism of Xenobiotics Human Environments
  6. Edward Croom

  7. Toxic Endpoints in the Study of Human Exposure to Environmental Chemicals
  8. Andrew D. Wallace

  9. Pesticide Regulations: Exposure-Dose Modeling from FIFRA to FQPA
  10. James B. Knaak, Cecilla Tan and Curt C. Dary

  11. Occupational Chemicals: Metabolism, Toxicity and Mode of Action
  12. Sheila Flack and Leena A. Nylander-French

  13. Chemicals of Military Deployments: Revisiting Gulf War Syndrome in Light of New Information
  14. A.A. Brimfield

  15. Pharmaceuticals in the Environment: Lessons Learned for Reducing Uncertainties in Environmental Risk Assessment
  16. Bryan W. Brooks, Jason P. Berninger, Lauren A. Kristofco, Alejandro J. Ramirez, Jacob K. Stanley and Theodore W. Valenti

  17. Quantitative Risk Assessment Methods for Cancer and Non-Cancer Effects
  18. Ronald E. Baynes

  19. Human Health Risk Assessment for Contaminated Properties
  20. Atul M. Salhotra

  21. The Future of Human Health Risk Assessment of Environmental Chemicals.
  22. Ernest Hodgson

  23. Ecological Risk Assessment
  24. Damian Shea and Waverly Thorsen

  25. Metabolic Interactions of Environmental Toxicants in Humans
  26. Ernest Hodgson

  27. Toxins and Venoms
  28. Ernest Hodgson

  29. Summary and Conclusions


No. of pages:
© 2012
Academic Press
Print ISBN:
Electronic ISBN:


Praise for the series:
"Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal