Tissue Engineering Using Ceramics and Polymers

Tissue Engineering Using Ceramics and Polymers

3rd Edition - October 27, 2021

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  • Editors: Aldo Boccaccini, P.X. Ma, Liliana Liverani
  • Paperback ISBN: 9780128205082
  • eBook ISBN: 9780128205792

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Description

Tissue Engineering Using Ceramics and Polymers, Third Edition is a valuable reference tool for both academic researchers and scientists involved in biomaterials or tissue engineering, including the areas of bone and soft-tissue reconstruction, repair and organ regeneration. With its distinguished editors and international team of contributors, this book reviews the latest research and advances in this thriving area and how they can be used to develop treatments for disease states. New sections cover nanobiomaterials, drug delivery, advanced imaging and MRI for tissue engineering, and characterization of vascularized scaffolds. Technology and research in the field of tissue engineering has drastically increased within the last few years to the extent that almost every tissue and organ of the human body could potentially be regenerated with the aid of biomaterials.  

Key Features

  • Provides updated and new information on ceramic and polymer biomaterials for tissue engineering
  • Presents readers with systematic coverage of the processing, characterization and modeling of each material
  • Includes content that will be relevant to a range of readers, including biomedical engineers, materials scientists, and those interested in regenerative medicine

Readership

Materials scientists and biomedical engineers in academia and research, interested in developing optimal materials for tissue engineering

Table of Contents

  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • Contributors
  • About the editors
  • Foreword
  • Preface
  • References
  • Part I: General issues: Materials
  • Chapter 1: Ceramic biomaterials for tissue engineering
  • Abstract
  • 1.1: Introduction
  • 1.2: Bioceramics
  • 1.3: Substitutions of hydroxyapatite
  • 1.4: Bioactive ceramic composites
  • 1.5: Properties of ceramics
  • 1.6: Processing of ceramics
  • 1.7: Characterization techniques
  • 1.8: Conclusions and future trends
  • References
  • Further reading
  • Chapter 2: Synthetic polymeric biomaterials for tissue engineering
  • Abstract
  • 2.1: Introduction
  • 2.2: Synthetic polymeric scaffolds for tissue engineering
  • 2.3: Polymeric scaffolds with controlled release capacity
  • 2.4: Conclusions and future trends
  • References
  • Chapter 3: Natural polymeric biomaterials for tissue engineering
  • Abstract
  • Acknowledgments
  • 3.1: Introduction
  • 3.2: Natural biopolymers
  • 3.3: Natural biopolymers-based scaffolding strategies for tissue engineering/regeneration
  • 3.4: Conclusions and future trends
  • References
  • Further reading
  • Chapter 4: Bioactive glasses and ceramics for tissue engineering
  • Abstract
  • 4.1: Introduction
  • 4.2: From ceramic and glass monoliths to scaffolds for tissue engineering
  • 4.3: Bioactive ceramics
  • 4.4: Properties of bioactive ceramics
  • 4.5: Tissue engineering applications of bioactive ceramics
  • 4.6: Bioactive glasses
  • 4.7: Preparation and properties of bioactive glasses
  • 4.8: Bioactive glasses in tissue engineering
  • 4.9: Bioactive glass − ceramics
  • 4.10: Bioactive composites
  • 4.11: Conclusions and future trends
  • References
  • Chapter 5: Biodegradable and bioactive polymer/inorganic phase composites
  • Abstract
  • 5.1: Introduction
  • 5.2: Tuning of biomaterial properties in composites
  • 5.3: From micro to nano: How the scale influences material properties
  • 5.4: Composite processing
  • 5.5: Applications of composites in tissue engineering
  • 5.6: Conclusions and future trends
  • References
  • Part II: General issues: Processing and characterization
  • Chapter 6: Overview of scaffolds processing technologies
  • Abstract
  • 6.1: Introduction
  • 6.2: Conventional technologies
  • 6.3: Additive manufacturing
  • 6.4: Conclusions and future trends
  • References
  • Chapter 7: Transplantation of engineered cells and tissues
  • Abstract
  • Acknowledgements
  • 7.1: Introduction
  • 7.2: Lack of rejection of tissue engineered products
  • 7.3: Testing and regulatory consequences
  • 7.4: Generality of the resistance of tissue-engineered products to immune rejection
  • 7.5: Manufacturing consequences
  • 7.6: Conclusions and future directions
  • 7.7: Discussion of the literature
  • References
  • Chapter 8: Advanced imaging/MRI for tissue engineering
  • Abstract
  • 8.1: Introduction
  • 8.2: MRI techniques
  • 8.3: MRI in tissue engineering
  • 8.4: Advanced non-MRI techniques
  • 8.5: Conclusions and future trends
  • References
  • Chapter 9: Nanoscale design in biomineralization for developing new biomaterials
  • Abstract
  • 9.1: Introduction
  • 9.2: Bone
  • 9.3: Bone tissue engineering
  • 9.4: Biomineralization
  • 9.5: Silica-based nanoparticles
  • 9.6: Nanocomposites
  • 9.7: Conclusions and future trends
  • References
  • Chapter 10: Additive manufacturing of polymers and ceramics for tissue engineering applications
  • Abstract
  • 10.1: Introduction
  • 10.2: Additive manufacturing technologies
  • 10.3: Additive manufacturing of polymers
  • 10.4: Additive manufacturing of ceramics
  • 10.5: Additive manufacturing of polymer-ceramic composites
  • 10.6: Bioprinting
  • 10.7: Conclusions and future trends
  • References
  • Part III: Tissue and organ regeneration
  • Chapter 11: Myocardial tissue engineering
  • Abstract
  • Acknowledgments
  • 11.1: Introduction
  • 11.2: Cells used in MTE
  • 11.3: Scaffolds in MTE
  • 11.4: Biomaterials used in MTE
  • 11.5: Conclusions and future trends
  • References
  • Further reading
  • Chapter 12: Bladder tissue regeneration
  • Abstract
  • 12.1: Introduction
  • 12.2: Bladder reconstruction approaches using cells, biomaterials and tissue engineering
  • 12.3: Review of bladder tissue engineering studies
  • 12.4: Conclusions and future trends
  • References
  • Chapter 13: Peripheral nerve tissue engineering
  • Abstract
  • Acknowledgements
  • 13.1: Overview of the nervous system
  • 13.2: Peripheral nerves
  • 13.3: Nerve injury and axon regeneration
  • 13.4: Peripheral nerve gap repair—The gold standard
  • 13.5: Nerve conduits (NCs)
  • 13.6: Materials for NCs
  • 13.7: Fabrication of NCs
  • 13.8: Structural modifications of NCs
  • 13.9: Cells for nerve repair
  • 13.10: Cell-derived factors for regeneration
  • 13.11: Conclusions and future trends
  • References
  • Chapter 14: Skeletal muscle tissue engineering
  • Abstract
  • 14.1: Introduction
  • 14.2: Skeletal muscle anatomy
  • 14.3: Tissue engineering of skeletal muscle
  • 14.4: 3-D matrices for skeletal muscle tissue engineering
  • 14.5: Polymeric materials for electrospun nanofibers
  • 14.6: Mechanical and electrical stimulation of engineered skeletal muscle
  • 14.7: Vascularization and in vivo generation of 3-D muscle tissue
  • 14.8: Conclusions and future trends
  • References
  • Chapter 15: Cartilage tissue engineering
  • Abstract
  • 15.1: Introduction
  • 15.2: Relevance of articular cartilage repair
  • 15.3: Biology of articular cartilage
  • 15.4: Repair of articular cartilage
  • 15.5: Scaffold-based strategies for cartilage repair
  • 15.6: Conclusions and future trends
  • References
  • Chapter 16: Bone tissue engineering
  • Abstract
  • Acknowledgments
  • 16.1: Introduction
  • 16.2: Bone tissue engineering: Native bone properties
  • 16.3: Bone tissue engineering: Design considerations
  • 16.4: Bone tissue engineering: Material approaches
  • 16.5: Bone tissue engineering: Pre-clinical translation
  • 16.6: Conclusions and future trends
  • References
  • Chapter 17: Nanofibrous scaffolds for skin tissue engineering and wound healing applications
  • Abstract
  • Acknowledgments
  • 17.1: Introduction
  • 17.2: Electrospinning as a constantly evolving technique for tissue engineering
  • 17.3: Electrospun scaffolds for skin tissue regeneration
  • 17.4: Electrospun scaffolds for wound healing
  • 17.5: Conclusions and future trends
  • References
  • Chapter 18: Interface tissue engineering
  • Abstract
  • 18.1: Introduction
  • 18.2: Heterotypic interfaces: Ligament-to-bone
  • 18.3: Heterotypic interfaces: Tendon-to-bone
  • 18.4: Heterotypic interfaces: Cartilage-to-bone
  • 18.5: Homotypic interfaces: Cartilage-to-cartilage
  • 18.6: Conclusions and future trends
  • References
  • Chapter 19: Bioceramic nanoparticles in tissue engineering and drug delivery
  • Abstract
  • 19.1: Introduction
  • 19.2: Ceramic nanoparticles
  • 19.3: Nanoparticles for drug delivery
  • 19.4: Nanoparticles for gene transfer (transfection)
  • 19.5: Nanoparticles for gene silencing
  • 19.6: Fluorescent nanoparticles for imaging
  • 19.7: Nanoparticles in tissue engineering
  • 19.8: Conclusions and future trends
  • References
  • Chapter 20: Natural hydrogels for bone tissue engineering
  • Abstract
  • 20.1: Introduction
  • 20.2: Biological cues mimicking the osteogenic niche
  • 20.3: Natural hydrogel materials
  • 20.4: Conclusion and future trends
  • References
  • Chapter 21: Dense collagen-based scaffolds for soft tissue engineering applications
  • Abstract
  • 21.1: Introduction
  • 21.2: Collagen for tissue engineering
  • 21.3: Dense collagen for soft tissue engineering
  • 21.4: Potential in ligament and tendon tissue engineering applications
  • 21.5: Conclusions and future trends
  • References
  • Chapter 22: Female reproductive organs tissue engineering
  • Abstract
  • 22.1: Introduction
  • 22.2: Fertility preservation treatments: State-of-the art
  • 22.3: Uterus
  • 22.4: Ovary
  • 22.5: Fallopian tubes
  • 22.6: Placenta
  • 22.7: Conclusions and future trends
  • References
  • Chapter 23: Scaffolds with drug delivery capability
  • Abstract
  • 23.1: Introduction
  • 23.2: Composite scaffolds for bone tissue engineering
  • 23.3: Conclusions and future trends
  • References
  • Index

Product details

  • No. of pages: 888
  • Language: English
  • Copyright: © Woodhead Publishing 2021
  • Published: October 27, 2021
  • Imprint: Woodhead Publishing
  • Paperback ISBN: 9780128205082
  • eBook ISBN: 9780128205792

About the Editors

Aldo Boccaccini

Aldo R. Boccaccini is Professor of Biomaterials and Head of the Institute of Biomaterials at the Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Germany. Prior to this appointment, he was Professor of Materials Science and Engineering at Imperial College London, UK (2000-2009). He has remained Visiting Professor of Materials at Imperial College London. He is also visiting professor at Nagoya Institute of Technology (Japan), RWTH Aachen University (Germany) and Universidad Nacional de Cuyo (Argentina). The research activities of Prof. Boccaccini are in the broad area of glasses, ceramics and polymer/glass composites for biomedical, functional and/or structural applications. Prof. Boccaccini has also developed the electrophoretic deposition technique for production of nanostructured materials and composites with defined surface topography with potential use in the biomedical field. He is the author or co-author of more than 450 scientific papers and 15 book chapters. Boccaccini is Fellow of the Institute of Materials, Minerals and Mining (UK) and of the American Ceramic Society. He is the Editor-in-Chief of the journal “Materials Letters” (Elsevier) and serves in the editorial board of several recognized international journals. He has also edited two books with Elsevier.

Affiliations and Expertise

Professor of Biomaterials, Head of the Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Germany

P.X. Ma

Ma is the Richard H Kingery Endowed Collegiate Professor of Biologic and Materials Sciences, Biomedical Engineering, Materials Science and Engineering, and Macromolecular Science and Engineering at the University of Michigan. His research is in the areas of biomaterials, biomedical polymers, controlled release, tissue engineering, and regenerative medicine. Among various recognitions, Dr. Ma was named one of the Top 100 materials scientists in the world by Thomson Reuters. He is an elected Fellow of the American Institute for Medical and Biological Engineering, Fellow of Biomaterials Science and Engineering, Fellow of the Materials Research Society and Fellow of American Association for the Advancement of Science.

Affiliations and Expertise

Richard H Kingery Endowed Collegiate Professor, University of Michigan, USA

Liliana Liverani

Liliana Liverani is a Senior Researcher at the Institute of Biomaterials, University of Erlangen-Nuremberg. She has expertise on the synthesis and functionalization of polymers and composites for tissue engineering applications, mainly by using the electrospinning technique.

Affiliations and Expertise

Senior Research Associate, Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Germany

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