Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics - 7th Edition - ISBN: 9781455741656, 9780323239189

Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics

7th Edition

Authors: Carl Burtis David Bruns
Hardcover ISBN: 9781455741656
eBook ISBN: 9780323239189
Imprint: Saunders
Published Date: 24th April 2014
Page Count: 1104


A condensed, easier-to-understand student version of the acclaimed Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 7th Edition uses a laboratory perspective in providing the clinical chemistry fundamentals you need to work in a real-world, clinical lab. Coverage ranges from laboratory principles to analytical techniques and instrumentation, analytes, pathophysiology, and more. New content keeps you current with the latest developments in molecular diagnostics. From highly respected clinical chemistry experts Carl Burtis and David Bruns, this textbook shows how to select and perform diagnostic lab tests, and accurately evaluate results.

Key Features

  • Authoritative, respected author team consists of two well-known experts in the clinical chemistry world.
  • Coverage of analytical techniques and instrumentation includes optical techniques, electrochemistry, electrophoresis, chromatography, mass spectrometry, enzymology, immunochemical techniques, microchips, automation, and point of care testing.
  • Learning objectives begin each chapter, providing measurable outcomes to achieve after completing the material.
  • Key words are listed and defined at the beginning of each chapter, and bolded in the text.
  • A glossary at the end of the book makes it quick and easy to look up definitions of key terms.
  • More than 500 illustrations plus easy-to-read tables help you understand and remember key concepts.

Table of Contents

1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
3. Clinical Evaluation of Methods 
4. Evidence-Based Laboratory Medicine
5. Establishment and Use of Reference Values
6. Specimen Collection, Processing, and Other Preanalytical Variables
7. Quality Management
8. Principles of Basic Techniques and Laboratory Safety
9. Optical Techniques 
10. Electrochemistry and Chemical Sensors 
11. Electrophoresis 
12. Chromatography 
13. Mass Spectrometry 
14. Enzyme and Rate Analyses 
15. Immunochemical Techniques 
16 Automation
17. Point-of-Care Instrumentation 
18. Amino Acids, Peptides, and Proteins 
19. Serum Enzymes
20. Tumor Markers and Cancer Genes
21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
22. Carbohydrates 
23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
24. Electrolytes and Blood Gases 
25. Hormones
26.  Catecholamines and Serotonin
27.  Vitamins, Trace Elements, Nutritional Assessment
28. Hemoglobin, Iron, and Bilirubin 
29. Porphyrins and Porphyrias 
30. Therapeutic Drugs and Their Management
31. Clinical Toxicology 
32.  Toxic Metals
33. Diabetes
34.  Cardiovascular Disease
35.  Kidney Disease 
36.  Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
37.  Liver Disease 
38.  G


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About the Author

Carl Burtis

Affiliations and Expertise

Health Services Division, Oak Ridge National Laboratory, Oak Ridge, TN, and Clinical Professor of Pathology, University of Utah School of Medicine, Salt Lake City, UT

David Bruns

Affiliations and Expertise

Professor of Pathology, University of Virginia School of Medicine, Director of Clinical Chemistry and Associate Director of Molecular Diagnostics, University of Virginia Health System, Charlottesville, VA, and Former Editor, Clinical Chemistry, Washington, DC


NEW REVIEW -- BURTIS / Tietz Fundamentals of Clinical Chemistry, 6th Edition.
Elsevier, 2008, $96.95. Imprint: Saunders.

Burtis, Carl A., PhD; Ashwood, Edward R., MD; Bruns, David E., MD

ISBN: 978-0-7216-3865-2, NLM: QY 90, LC: RB40, 952 pages, hard cover.


Valerie L. Ng, PhD, MD(Alameda County Medical Center/Highland Hospital)

This is the sixth edition of what is appropriately recognized as one of the cornerstone reference books for clinical chemistry. The fifth edition was published 2001.

This is as a comprehensive clinical chemistry book.

Intended for anyone interested in clinical chemistry, the book would be of obvious use to clinical laboratory scientists (practicing or in training) or clinical chemists (fellows or practicing). It would also be of interest to clinical pathologists (residents or practicing). Finally, it would be of interest to anyone who orders any of these tests and uses them to help in clinical care (i.e., MDs, medical students, residents, fellows, nurse practitioners, etc.) The editors and authors are well known and credible authorities.

Every time I turn around, there's a new Tietz clone. Specifically, all released within the past year or so and all edited by the same group, there is this sixth edition, there is the fourth edition of the Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, Burtis et al. (Elsevier,
2006) (mammoth combo book), and there is the newly released Fundamentals of Molecular Diagnostics, Bruns et al (Elsevier, 2007). How do these three books interrelate? This sixth edition nicely carries on the tradition of excellence long associated with Tietz Fundamentals of Clinical Chemistry. Of note and unique to this book (co