Thermal Ablation Therapy

Thermal Ablation Therapy

Theory and Simulation

1st Edition - May 18, 2021

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  • Authors: Amira Ashour, Yanhui Guo, Waleed Mohamed
  • Paperback ISBN: 9780128195444
  • eBook ISBN: 9780128231562

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Thermal Ablation Therapy: Theory and Simulation includes detailed theoretical and technical concepts of thermal ablation therapy in different body organs. Concepts of ablation technology based on different thermal ablation methods are introduced, along with changes in the tissues’ mechanical properties due to thermal denaturation. The book emphasizes the mathematical and engineering concepts of RF and MW energy propagation through tissues and where high heating rates produced by MW systems can overcome the heat-sink effects from nearby vessels. The design and tuning of the MW antennas to deliver energy efficiently to specific organ systems such as the liver or lung is also covered. Other sections cover the computational modeling of radiofrequency ablation and microwave ablation procedures for developing and implementing new efficient ablation in clinical systems, numerical simulations for different scenarios of different organs with different size using RF and MW ablation systems with different antennas’/probes design and configurations, and numerical techniques for temperature profile in tissues.

Key Features

  • Presents the latest mathematical models of microwave and RF ablation theories
  • Discusses the biological responses and engineering principles by which thermal ablation techniques can provide temperature-elevation within the organs of the human body, including action mechanisms, required equipment, needle characteristics and treatment techniques
  • Highlights the different techniques of thermal ablation, including radiofrequency ablation, microwave ablation, laser ablation, and ultrasound ablation, nanotechnology, and the different metrics used to evaluate the performance of the used antenna within the ablation needle


Biomedical engineers researching and designing thermal ablation systems, computer/data scientists researching and developing algorithms, models, and simulations related to thermal ablation therapy, electrical and electronics engineers Research scientists in medical and biological sciences, clinicians in internal medicine

Table of Contents

  • 1. Introduction
    2. Ablation Techniques Overview
    3. Mathematics and Finite Element Method of Thermal Ablation Therapy
    4. Clinical Applications of Thermal Ablation
    5. Ablation Probes
    6. COMSOL Multiphysics Software for Ablation System Simulation
    7. Simulation-driven Modelling of Radiofrequency Ablation System
    8. Simulation-driven Modelling of Microwave Ablation System
    9. Image-Guided based Thermal Ablation Therapy
    10. Challenges and Future Research Directions

Product details

  • No. of pages: 466
  • Language: English
  • Copyright: © Academic Press 2021
  • Published: May 18, 2021
  • Imprint: Academic Press
  • Paperback ISBN: 9780128195444
  • eBook ISBN: 9780128231562

About the Authors

Amira Ashour

Amira S. Ashour is an Assistant Professor and Head of Electronics and Electrical Communications Engineering Department, Faculty of Engineering, Tanta University, Egypt. She is a member in the Research and Development Unit, Faculty of Engineering, Tanta University, Egypt. She received the B.Eng. degree in Electrical Engineering from Faculty of Engineering, Tanta University, Egypt in 1997, M.Sc. in Image Processing in 2001 and Ph.D. in Smart Antenna in 2005 from Faculty of Engineering, Tanta University, Egypt. Ashour has been the Vice Chair of Computer Engineering Department, Computers and Information Technology College, Taif University, KSA for one year from 2015. She has been the vice chair of CS department, CIT college, Taif University, KSA for 5 years. Her research interests are Smart antenna, Direction of arrival estimation, Targets tracking, Image processing, Medical imaging, Machine learning, Biomedical Systems, Pattern recognition, Image analysis, Computer vision, Computer-aided detection and diagnosis systems, Optimization, and Neutrosophic theory. She has 15 books and about 150 published journal papers. She is an Editor-in-Chief for the International Journal of Synthetic Emotions (IJSE), IGI Global, US.

Affiliations and Expertise

Assistant Professor and Head of Electronics and Electrical Communications Engineering Department, Faculty of Engineering, Tanta University, Egypt

Yanhui Guo

Yanhui Guo is currently an Assistant professor in the Department of Computer Science at the University of Illinois at Springfield, USA. He received his B. S. degree in Automatic Control from Zhengzhou University, China, M.S. degree in Pattern Recognition and Intelligence System from Harbin Institute of Technology, China, and Ph.D. degree in the Department of Computer Science, Utah State University, USA. Dr. Guo has published more than 80 journal papers and 30 top conference papers, completed 11 grant funded research projects, and worked as an associate editor of different international journals, reviewers for top journals and conferences. His research area includes neutrosophic theory, computer vision, machine learning, big data analytics, computer aided detection/diagnosis, and computer assist surgery.

Affiliations and Expertise

Assistant Professor, Department of Computer Science, University of Illinois, Springfield, USA

Waleed Mohamed

Waleed S. Mohamed received his MSc. in Internal Medicine from Faculty of Medicine, Tanta University, Egypt in 1993 and M.D in Internal Medicine, Faculty of Medicine, Tanta University, Egypt in 2000. He is Professor of Internal Medicine, Faculty of Medicine, Tanta University, Egypt from 2011 till now. Prof. Waleed is currently the Head of the Gastroenterology and Hepatology Unit, Faculty of Medicine, Tanta Univ., Egypt. He is Consultant of Gastroenterology & Diabetology and Consultant of Ultrasonography and Color Doppler in Tanta University, Faculty of Medicine, Tanta University, Egypt and previously the same in Taif University, KSA for 10 years from 2006 till 2016. He was Professor and chairperson of Human Resource Unit, Taif College of Medicine, Taif University, KSA for 10 years. He was the Medical director of Taif University Medical Outpatient Clinics, KSA for 10 years from 2006. He is member in the editorial board of the Immunoendocrinology journal and Journal of Liver and Pancreatic Diseases (JLPD). He is a reviewer in several international journals. His research interests include Hepatology, Gastroenterology, Non-alcoholic fatty liver disease, Obesity, Diabetes Mellitus, Herbal medicine, Medical education and Healthcare quality. He has 2 books and 60 published papers in international journals and conferences. He is a life member of Egyptian Society of Blood Diseases, Arab Society for Studying Liver Diseases, Egyptian Association of Kidney, Egyptian Association of Liver, Gastrointestinal and Tropical Diseases and Egyptian Association of Diabetes and Metabolism.

Affiliations and Expertise

Professor, Department of Internal Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt

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