Therapy in Neurology, An Issue of Neurologic Clinics

1st Edition, Volume 39-1 - November 24, 2020
Editor: Jose Biller
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 7 1 2 8 1 - 1
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 7 1 2 8 2 - 8

This issue of Neurologic Clinics, guest edited by Dr. José Biller, is devoted to Therapy in Neurology. This issue is one of four selected each year by the series Consulting Editor,… Read more

Therapy in Neurology, An Issue of Neurologic Clinics

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This issue of Neurologic Clinics, guest edited by Dr. José Biller, is devoted to Therapy in Neurology. This issue is one of four selected each year by the series Consulting Editor, Dr. Randolph W. Evan. Articles in this issue include: Update on CGRP Antagonism in the Treatment of Migraine, Advances in the Treatment of Multiple Sclerosis, Advances in the Treatment of Neuromyelitis Optica Spectrum Disorder, Advances and ongoing controversies in PFO closure and cryptogenic stroke, Advances in neuromodulation/neurostimulation in Neurology, Advances in the treatment of muscular dystrophies and motor neuron disorders, Advances in the management of small fiber neuropathies, Update in the treatment of Idiopathic Intracranial Hypertension, What is new in neuro-oncology?, Advances in the surgical management of epilepsy, Treatment of Viral Encephalitis, An update on Botulinum toxin in neurology, Cannabinoids in neurological illnesses, and Pitfalls in Transitioning Neurological Care of the Developmentally Disabled from Pediatric to Adult Providers.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Preface
Update on Calcitonin Gene-Related Peptide Antagonism in the Treatment of Migraine
Key points
Introduction
Calcitonin gene-related peptide mechanism
Anti–calcitonin gene-related peptide mechanisms
Efficacy and safety
Unanswered questions
Summary
Advances in the Treatment of Multiple Sclerosis
Key points
Introduction
Disease-modifying therapies
Stem cell transplant
Treatment strategies for relapsing remitting multiple sclerosis
Progressive disease
Discussion
Advances in the Treatment of Neuromyelitis Optica Spectrum Disorder
Key points
Introduction
Management of relapses
Disease-modifying therapies: B-cell depletion therapies
Disease-modifying therapies: interleukin-6 antagonists
Disease-modifying therapies: complement inhibitors
Disease-modifying therapies: broad-spectrum immunosuppressants
Autologous hematopoietic stem cell transplant as a disease-modifying therapy
Summary
Clinics care points
Advances and Ongoing Controversies in Patent Foramen Ovale Closure and Cryptogenic Stroke
Key points
Introduction
Patent foramen ovale closure versus medical treatment
Diagnosis and characterization of patent foramen ovale
Patient selection
Summary
Advances and Future Directions of Neuromodulation in Neurologic Disorders
Key points
Introduction
Advances in understanding of mechanism of action
Parkinson disease
Essential tremor
Dystonia
Tourette syndrome
Tardive dyskinesia and chorea
Dementia
Epilepsy
Pain
Discussion and future directions
Advances in Treatments in Muscular Dystrophies and Motor Neuron Disorders
Key points
Introduction
Approaches in gene therapy
X-linked dystrophies
Limb-girdle muscular dystrophies
Facioscapulohumeral muscular dystrophy
Motor neuron diseases
Future directions
Summary
Advances in the Management of Small Fiber Neuropathy
Key points
Background
Small fiber neuropathy diagnostics
Objective small fiber neuropathy follow-up parameters
Small fiber neuropathy misdiagnosed as other conditions
Small fiber neuropathy caused by inherited conditions
Novel immune biomarkers in small fiber neuropathy
Treatment with intravenous immunoglobulin
Summary
Clinics care points
Update in the Management of Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome
Key points
Myasthenia gravis
Lambert-Eaton myasthenic syndrome
Clinics care points
Update in the Management of Idiopathic Intracranial Hypertension
Key points
Introduction
Assessment and monitoring of the patient with idiopathic intracranial hypertension
Treatment of the patient with idiopathic intracranial hypertension
Summary
Clinics care points
What is New in Neuro-oncology?
Key points
Introduction
Update on brain tumor classification
Update on diagnostics
Update on brain tumor therapeutics
Other novel approaches
Summary
Clinics care points
Advances in the Surgical Management of Epilepsy: Drug-Resistant Focal Epilepsy in the Adult Patient
Key points
Introduction
Beneficial effects of surgery
Diagnostic evaluation
Surgical management of focal epilepsy
Epilepsy surgery in contemporary practice
Resources
Clinics care points
Treatment of Viral Encephalitis
Key points
Introduction
Herpetic viral encephalitides
Non-herpetic viral encephalitides
Progressive multifocal leukoencephalopathy
Summary
An Update on Botulinum Toxin in Neurology
Key points
Background
Treatment-related issues
Botulinum toxin for head/neck indications
Sialorrhea
Cervical dystonia
Limb dystonia
Truncal dystonia
Limb spasticity
Botulinum neurotoxin for other indications
Summary
Clinics care points
Cannabinoids in Neurologic Illnesses
Key points
Introduction
Content
Summary
CLINICS CARE POINTS
Therapeutic Pitfalls in the Transition of Neurologic Patients from Pediatric to Adult Health Care Providers
Key points
Epilepsy
Headaches
Attention-Deficit Hyperactivity Disorder
Autism spectrum disorders
Cerebrovascular disease
Hydrocephalus
Myelomeningocele
Brain tumors
Neuromuscular disorders
Summary
Clinics care points

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Jose Biller