Therapeutic Proteins and Peptides - 1st Edition - ISBN: 9780128143407, 9780128143414

Therapeutic Proteins and Peptides, Volume 112

1st Edition

Serial Editors: Rossen Donev
eBook ISBN: 9780128143414
Hardcover ISBN: 9780128143407
Imprint: Academic Press
Published Date: 20th April 2018
Page Count: 408
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Table of Contents

1. Rational Design of Liquid Formulations of Proteins

Mark C. Manning, Jun Liu, Tiansheng Li and Ryan E. Holcomb

2. Therapeutic Monoclonal Antibodies Delivery for the Glioblastoma Treatment

Flávia Sousa, Rui P. Moura, Elias Moreira, Cláudia Martins and Bruno Sarmento

3. Dynamical Behavior of Somatostatin-14 and Its Cyclic Analogues as Analyzed in Bulk and on Plasmonic Silver Nanoparticles

Belén Hernández, Yves-Marie Coïc, Eduardo López-Tobar, Santiago Sanchez-Cortes, Bruno Baron, Fernando Pflüger, Sergei G. Kruglik, Régis Cohen and Mahmoud Ghomi

4. Transglutaminase and Sialyltransferase Enzymatic Approaches for Polymer Conjugation to Proteins

Katia Maso, Antonella Grigoletto and Gianfranco Pasut

5. Chimeric Small Antibody Fragments as Strategy to Deliver Therapeutic Payloads

Sandra Aguiar, Joana Dias, Ana M. Manuel, Roberto Russo, Pedro M. P. Gois, Frederico A. da Silva and Joao Goncalves

6. Smart Cell-Penetrating Peptide-Based Techniques for Intracellular Delivery of Therapeutic Macromolecules

Yang He, Feng Li and Yongzhuo Huang

7. In Silico Tools and Databases for Designing Peptide-Based Vaccine and Drugs

Salman S. Usmani, Rajesh Kumar, Sherry Bhalla, Vinod Kumar and
Gajendra P.S. Raghava

8. Protein and Peptides for Elderly Health

Nan Shang, Chalamaiah Meram, Nandika Bandara and Jianping Wu

9. Peptide Derivates of Erythropoietin in the Treatment of Neuroinflammation and Neurodegeneration

Ilkcan Ercan, Kemal U. Tufekci, Ezgi Karaca, Sermin Genc and Kursad Genc

10. The Structure/Function Relationship in Antimicrobial Peptides: What Can we Obtain From Structural Data?

Marlon H. Cardoso, Karen G. N. Oshiro, Samilla B. Rezende, Elizabete S. Cândido and Octávio L. Franco

11. Linear Analogues of Lipopeptide Battacin With Potent In Vitro Activity Against S. aureus

Hugh D. Glossop, Esperanza Pearl, Gayan H. De Zoysa and Vijayalekshmi Sarojini


Therapeutic Proteins and Peptides, Volume 112 in an ongoing series promotes further research in the discovery of new therapeutic targets that can be affected by therapeutic proteins and peptides to cure or manage symptoms of human diseases, with this release focusing on the Rational Design of Stable Liquid Formulations of Biopharmaceuticals, Formulation strategies for peptides, proteins and antibodies using nanotechnology, the Solution structural dynamics of therapeutic peptides and their adsorption on plasmonic nanoparticles, Enzymatic approaches of protein-polymer conjugation, Chimeric small antibody fragments as a strategy to deliver therapeutic payloads, Smart cell-penetrating peptide-based techniques for cytoplasmic delivery of therapeutic macromolecules, and more.

Key Features

  • Describes advances in the discovery and application of therapeutic proteins/peptides which allow better targeting to the site of treatment and cause fewer adverse effects when compared to chemical compounds used for disease treatment
  • Targeted to a very wide audience of specialists, researchers and students
  • Written by well-renown authorities in their field
  • Includes a number of high quality illustrations, figures and tables


Pharmacologists, protein chemists, formulation specialists, medical doctors, cell biologists, immunologists, structural biologists, computational biochemists and other researchers working in this field. Articles published here would also be of a great benefit to medical, biology and pharmacology students specializing in this field


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Ratings and Reviews

About the Serial Editors

Rossen Donev Serial Editor

Rossen Donev received his PhD degree in 1999 from the Institute of Molecular Biology, Bulgarian Academy of Sciences. He did postdoctoral training at Imperial Cancer Research Fund, UK (renamed after the merger with Cancer Research Campaign to Cancer Research UK, London Research Institute) and Cardiff University. In 2010 Dr. Donev was appointed Senior Lecturer in Swansea University. Currently he is Head of Research at MicroPharm Ltd, UK and Director of Biomed Consult, UK. He has published more than 60 research papers, has chaired scientific meetings in Molecular Medicine and given plenary talks. Rossen Donev has consulted on projects related to development of treatments for neurodevelopmental disorders and cancer therapies. He serves as Editor-in-Chief of the Advances in Protein Chemistry and Structural Biology and on editorial board of several other journals. His research interests include signaling pathways involved in neuropsychiatric disorders and tumor escape from the immune system, and development of therapeutic strategies for their treatment. More recently he has focused on design of antibody-based oral treatment of pathological conditions of the colon and small intestines.

Affiliations and Expertise

Swansea University, UK