Therapeutic Drug Monitoring Data

Therapeutic Drug Monitoring Data

A Concise Guide

4th Edition - September 14, 2019

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  • Authors: Amitava Dasgupta, Matthew Krasowski
  • eBook ISBN: 9780128158500
  • Paperback ISBN: 9780128158494

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Therapeutic Drug Monitoring Data: A Concise Guide, Fourth Edition serves as a ready resource of information on commonly monitored drugs that will help readers make decisions relating to the monitoring and interpretation of results. It is an easy-to-read source of information on intended use, pharmacokinetics, therapeutic range, and toxic concentrations, as well as bioavailability, disposition, metabolism and the excretion of commonly monitored therapeutic drugs. This fully updated fourth edition includes sections on new anticonvulsants, anti-depressant and anti-HIV drugs, new drugs for advanced cancer treatment, and thoroughly updated chapters that address new pitfalls and problems in the lab.

Key Features

  • Serves as a ready resource of information for commonly monitored drugs
  • Presents a useful, quick guide for those making decisions related to monitoring and interpretation of results
  • Provides concise, easily digestible content for clinical laboratory scientists, toxicologists and clinicians


Pathologists, clinical chemists, and toxicologists; practicing clinicians, fellows and residents in pathology, internal medicine, emergency medicine and family practice

Table of Contents

  • 1. Pharmacokinetics and Therapeutic Drug Monitoring
    2. Before and After: The Preanalytical and Postanalytical Phases of Therapeutic Drug Monitoring
    3. Clinical Utility of Monitoring Free Drug Concentrations
    4. Effect of Bilirubin, Lipemia, Hemolysis, Paraproteins, and Heterophilic Antibodies on Immunoassays for Therapeutic Drug Monitoring
    5. Drug-Herb and Drug-Food Interactions and Effects on Therapeutic Drug Monitoring
    6. Monitoring Anticonvulsant Concentrations – General Considerations
    7. Therapeutic Drug Monitoring of Cardioactive Drugs
    8. Therapeutic Drug Monitoring of Antidepressants
    9. Introduction to Immunosuppressive Drug Monitoring
    10. Therapeutic Drug Monitoring of Antimicrobial and Antiviral Agents
    11. Therapeutic Drug Monitoring of Analgesics
    12. Therapeutic Drug Monitoring of Antineoplastic Drugs
    13. Caffeine, Lithium, and Theophylline

Product details

  • No. of pages: 382
  • Language: English
  • Copyright: © Academic Press 2019
  • Published: September 14, 2019
  • Imprint: Academic Press
  • eBook ISBN: 9780128158500
  • Paperback ISBN: 9780128158494

About the Authors

Amitava Dasgupta

Amitava Dasgupta
Dr. Amitava Dasgupta received his Ph.D degree in Chemistry from Stanford University and received his medical training in Toxicology and Clinical Chemistry from the Laboratory Medicine Department of the University of Washington School Of Medicine at Seattle. He is board certified in both Toxicology and Clinical Chemistry by the American Board of Clinical Chemistry. He is a tenured Full Professor of Pathology and Laboratory Medicine at the University of Texas Health Sciences Center located at the Texas Medical Center at Houston. He is also the Director of Clinical Chemistry and Toxicology Laboratory of Memorial-Hermann Laboratory Services, the major clinical teaching hospital of the University of Texas. In addition, he is also the Medical Director of Memorial-TIRR Hospital laboratory services. Dr. Dasgupta has published over 235 scientific papers and edited, co-edited, authored or co-authored 20 books including books published by Elsevier. He is on the Editorial Board of five major medical journals including American Journal of Clinical Pathology, Archives of Pathology and Laboratory Medicine, Therapeutic Drug Monitoring, Clinica Chimica Acta and Journal of Clinical Laboratory Analysis. He lectures both nationally and internationally on drug and alcohol testing and acts as an expert witness for the State of Texas for alcohol and drug related criminal prosecutions.

Affiliations and Expertise

Professor, Pathology and Laboratory Medicine, McGovern Medical School, The University of Texas, Houston, TX, USA

Matthew Krasowski

Matthew D. Krasowski, MD, PhD is a clinical pathologist and the Walter L. Bierring Professor of Clinical Education at the University of Iowa Carver College of Medicine. He currently serves as the Vice Chair of Clinical Pathology and Laboratory Services in the Department of Pathology at University of Iowa Hospitals and Clinics.

Affiliations and Expertise

Department of Pathology and Laboratory Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA

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