Readership

Biochemists, chemists, professional researchers in laboratories in academic, government and corporate environments studying translational science, medicine and pharmacology, as well as, advanced undergraduate students, graduate students and medical students.

Table of Contents

Dedication

Preface

1. Introduction

2. DNA and RNA Quadruplex Structures

3. The Structures of Human Telomeric DNA Quadruplexes

4. Telomeric Quadruplex Ligands I

5. Telomeric Quadruplex Ligands II

6. The Biology and Pharmacology of Telomeric Quadruplex Ligands

7. Genomic Quadruplexes as Therapeutic Targets

8. RNA Quadruplexes

9. Design Principles for Quadruplex-binding Small Molecules

10. The Determination of Quadruplex Structures

Index

Details

No. of pages:
208
Language:
English
Copyright:
© 2012
Published:
Imprint:
Academic Press
Print ISBN:
9780123751386
Electronic ISBN:
9780123751393

About the author

Stephen Neidle

Stephen Neidle, DSc, PhD, ARCS, FRSC, Director of Cancer Research UK Biomolecular Structure Group, Director of the Centre for Cancer Medicines, Professor of Chemical Biology, The School of Pharmacy, University College London, UK

Affiliations and Expertise

The School of Pharmacy, University College London, UK