The Zebrafish in Biomedical Research - 1st Edition - ISBN: 9780128124314

The Zebrafish in Biomedical Research

1st Edition

Biology, Husbandry, Diseases, and Research Applications

Editors: Samual Cartner Judith Eisen Susan Farmer Karen Guillemin Michael Kent George Lawrence Sanders
Hardcover ISBN: 9780128124314
Imprint: Academic Press
Published Date: 1st August 2019
Page Count: 550
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Table of Contents

Introduction

1. History of Zebrafish Research

 

Biology Section

2. Taxonomy/Phylogeny

 

Appearance/Morphology/Anatomy & Development/Physiology (Morphophysiology)

General appearance/morphology

3. Head and Body

4. Integumentary System

5. Respiratory System

6. Skeletal System

7. Muscular System

 

Tissues and Organs Associated with Special Senses

8. Vision

9. Mechanosensory Lateral line System

10. Chemoreception

11. Hearing and Vestibular Function

 

Anatomy & Embryo Development

12. Head and Body

13. Digestive System

14. Cardiovascular System

15. Urinary System

16. Reproductive Systems

17. Endocrine Systems

18. Nervous Systems

19. Physiology, hematology, and clinical chemistry, gas exchange, hormonal regulation, regulatory osmolality

20. Immunology

21. Pigment/Chromophores

22. Sexual characteristics

23. Geographic Range/Natural Distribution

24. Natural History/Ecological Niche

25. Behavior of Wild Populations

26. Genetics

 

Husbandry Section

27. Introduction to Husbandry

28. Aquatics Facilities Design

29. Housing Types

30. Water Quality: definitions, effects on health, testing, normal values, equipment used, records

31. Filtration: definitions, testing methods, normal values, equipment used, records

32. Systems Maintenance and Troubleshooting: methods, equipment used, records

33. Cleaning and Disinfection of Life Systems: methods, equipment used, records

34. Feeding/Nutrition

35. Breeding/Colony Management

36. Larviculture

37. Importation and Quarantine

38. Exportation and Transport

39. Analgesia, Anesthesia, and Euthanasia

40. Regulatory Oversight, USA and internationally

41. Health Surveillance Programs

 

Diseases Section

42. Idiopathic and Water Quality Related Diseases

43. Parasitic Diseases: Including Microsporidia

44. Bacterial Diseases: Including Saprolegnia

45. Viral Diseases

46. Neoplasms (naturally occurring, associations with other diseases)

47. Special procedures (for disease diagnosis and treatment)

 

Research Section

48. Zebrafish as a Model to Understand Vertebrate Development

49. Zebrafish as a Model to Understand Neural Circuitry and Behavior

50. Zebrafish as a Model to Understand Human Genetic Diseases

51. Zebrafish as a Model to Understand Host-Microbe Interactions and Host-Pathogen Interactions

52. Zebrafish as a Platform for Technology Development

53. Zebrafish as a Platform for Genetic Screening

54. Zebrafish as a Platform for Toxicology and Drug Screening (or split into two)


Description

The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provide significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research.

Key Features

  • Presents a complete view of the zebrafish, covering their biology, husbandry, diseases and research applications
  • Includes the work of world-renowned editors
  • Provides the first authoritative and comprehensive treatment of zebrafish in biomedical research as part of the ACLAM series

Readership

Vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators/researchers using them to gain critical insights into human physiology and disease


Details

No. of pages:
550
Language:
English
Copyright:
© Academic Press 2019
Published:
Imprint:
Academic Press
Hardcover ISBN:
9780128124314

Ratings and Reviews


About the Editors

Samual Cartner Editor

Samuel Cartner, D.V. M., Ph.D., is the Assistant Vice President for Animal Research Services and Director of the Animal Resources Program (ARP) at the University of Alabama at Birmingham (UAB). He received his DVM from Auburn College of Veterinary Medicine and PhD from UAB. Dr. Cartner has served in multiple roles with organizations that promote premium laboratory animal care. Dr. Cartner is a faculty member in the Department of Genetics. His research interest includes genetic susceptibility to infectious disease, and the development of animal models of human and animal disease. Recently Dr. Cartner has focused on investigations that lead to improvements of laboratory animal care and use.

Affiliations and Expertise

Assistant Vice President, Animal Research Services and Director, Animal Resources Program (ARP), University of Alabama at Birmingham (UAB)

Judith Eisen Editor

Judith S. Eisen, Ph.D., earned her Doctorate at Brandeis University. She is a professor at the University of Oregon and a member of the Institute of Neuroscience at Oregon. The focus of Eisen’s research is to understand the mechanisms underlying development and function of the vertebrate nervous system. Eisen uses zebrafish in her research.

Affiliations and Expertise

Professor, Institute of Neuroscience, Department of Biology, University of Oregon, Eugene, OR, USA

Susan Farmer Editor

Susan C. Farmer, DVM, Ph.D., is the Senior Clinical Veterinarian and Co-Director of the Zebrafish Research Facility at the University of Alabama. Services offered by the facility are husbandry, larviculture, cryopreservation and research support. Dr. Farmer have her DVM degree from Mississippi State University and her Ph.D. in Pathology/Experimental Pathology from the University of Alabama at Birmingham.

Affiliations and Expertise

Co-Director, Zebrafish Research Facility and Assistant Director, Aquatics, Animal Resources Program, University of Alabama at Birmingham, Birmingham, AL, USA

Karen Guillemin Editor

Karen Guillemin, Ph.D., earned her Doctorate at Stanford University. She is a Professor at the University of Oregon and a member of the Institute of Molecular Biology at Oregon. Dr. Guillemin studies host-microbe interactions in development and disease, and uses zebrafish in her research.

Affiliations and Expertise

Professor, University of Oregon, Eugene, OR, USA

Michael Kent Editor

Michael Kent, Ph.D., is a Professor of Microbiology at Oregon State University in the College of Veterinary Medicine. Kent’s lab focuses on two major research areas: diseases of zebrafish in research facilities and impacts of pathogens on wild salmonid fishes. Dr. Kent is also a co-PI at the Zebrafish International Resource Center where he assists with health studies and their diagnostic service.

Affiliations and Expertise

Professor of Microbiology, College of Veterinary Medicine, Oregon State University, Eugene, OR, USA

George Lawrence Sanders Editor

George E. Sanders D.V.M., M.S. earned his Doctorate in Veterinary Medicine from Louisiana State University’s School of Veterinary Medicine. He received his Masters of Science in Comparative Medicine at the University of Washington. Dr Sanders is a Lecturer and is the Director of the Aquatic Animal Program, which provides multiple resources, training, instruction, and coordinates veterinary care for aquatic research animals at the University of Washington.

Affiliations and Expertise

Senior Lecturer and Director, Aquatic Animal Program, Comparative Medicine, University of Washington, Seattle, WA, USA