By using nanotechnological methods, we can now poke around protein molecules, genes, membranes, cells and more. Observation of such entities through optical and electron microscopes tempt us to touch and manipulate them. It is now possible to do so, and scientists around the world have started pulling, pushing and cutting small structures at the base of life processes to understand the effect of our hand work.The book describes the physical properties of such life supporting structures from the molecular level with a special emphasis on their designs based on the mechanical strength and flexibility, membrane and other biological nanostructures.
- Describes the basic mechanical features of proteins, DNA, cell membrane and other biological nanostructures - Explains the basic concepts and mathematics of elementary mechanics needed to understand and perform experimental work
This book is suitable for undergraduate and graduate students, and researchers in biochemistry, molecular biology, biophysics and cell biology who want to expand their knowledge from chemical description of life to a more physical one
Table of Contents
Preface Chapter 1. Force in Biology Chapter 2. Introduction to Basic Mechanics Chapter 3. Force and Force Measurement Apparatuses Chapter 4. Polymer Chain Mechanics Chapter 5. Interaction Forces Chapter 6. Single Molecule Interaction Forces Chapter 7. Single Molecule DNA and RNA Mechanics Chapter 8. Single Molecule Protein Mechanics Chapter 9. Motion in Nano-biology Chapter 10. Cell Mechanics Chapter 11. Manipulation at the Molecular Level Chapter 12. Finite Element Analysis of Microscopic Biological Structures Chapter 13. Appendices
Professor Atsushi Ikai graduated from the University of Tokyo with a BS in Biophysics and Biochemistry in 1965. He obtained his PhD in Physical Biochemistry from Duke University in 1971. He worked in protein denaturation and renaturation and then returned to the University of Tokyo to continue his work on protein science. He was appointed Professor of Biodynamics at Tokyo Institute of Technology in 1989. He has published 300 articles in international scientific journals.
Affiliations and Expertise
Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan