Description

This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights.

Key Features

This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights.

Readership

Researchers and students in cell, molecular and developmental biology

Table of Contents

Section I: Measuring and Modifying the UPR

  1. Methods for investigating the UPR in filamentous fungi
  2. Thomas Guillemette, Arthur F.J. Ram, Neuza D.S.P. Carvalho, Aymeric Joubert, Philippe Simoneau, David B. Archer

  3. Assays for detecting the unfolded protein response
  4. Karen Cawley, Shane Deegan, Afshin Samali, Sanjeev Gupta

  5. Analysis of the role of nerve growth factor in promoting cell survival during endoplasmic reticulum stress in PC12 cells
  6. Koji Shimoke , Harue Sasaya, and Toshihiko Ikeuchi

  7. Measuring ER stress and the unfolded protein response using mammalian tissue culture system
  8. Christine M. Oslowski and Fumihiko Urano

  9. Real-Time Monitoring of Er Stress in Living Cells And Animals Using Estrap Assay
  10. Masanori Kitamura and Nobuhiko Hiramatsu

  11. HIV protease inhibitors induce endoplasmic reticulum stress and disrupt barrier integrity in intestinal epithelial cells
  12. Huiping Zhou

  13. Dexamethasone induction of a heat-stress response
  14. José A. Guerrero, Vicente Vicente, Javier Corral

  15. Detecting and Quantitating Physiological Endoplasmic Reticulum Stress
  16. Ling Qi, Liu Yang and Hui Chen

    Section II: Molecular Components of the UPR

  17. PI 3-Kinase Regulatory Subunits as Regulators of the Unfolded Protein Response
  18. Jonathon N. Winnay and C. Ronald Kahn

  19. The Emerging Role of Histone Deacetylases (HDACs) in UPR regulation
  20. Soumen Kahali, Bhaswati Sarcar & Prakash Chinnaiyan

  21. Immunohistochemical detection of Activating Transcription Factor 3, a hub of the cellular adaptive-response network
  22. Tsonwin Hai, Swati Jalgaonkar, Christopher C. Wolford, and Xin Yin

  23. Experimental approaches for elucidation of stress-sensing

Details

No. of pages:
432
Language:
English
Copyright:
© 2011
Published:
Imprint:
Academic Press
Print ISBN:
9780123851147
Electronic ISBN:
9780123851154