The Structure and Function of Skin

The Structure and Function of Skin

3rd Edition - April 28, 1974

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  • Author: William Montagna
  • eBook ISBN: 9780323138697

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The Structure and Function of Skin, Third Edition is devoted to all matters pertaining to the structure and function of the skin. Drawing upon the accumulated data derived from embryology, histology, anatomy, physiology, biochemistry, and pharmacology, this book presents an overview of skin, with emphasis on human skin. Topics range from the biological functions of the dermis to the histochemical and microchemical properties of the epidermis; the effects of protein deficiency on hair growth; cutaneous innervation; nail regeneration and growth; sebaceous glands; and eccrine sweat glands. This book is organized into 12 chapters and begins with an overview of the structure and function of skin, and then discusses the epidermis and its structural features. Special consideration is given to the life cycle of epidermal cells; the properties and function of stratum corneum; and other cells in the epidermis including melanocytes, the cells of Langerhans, and Merkel cells. The chapters that follow focus on age-related changes in the dermis, cutaneous blood flow, changes in skin circulation, and the dermal nerve network. The book also considers hair growth and differentiation; the effects of malnutrition on the morphology of hair roots; and the structure and development of the nails. A chapter describing the cytochemistry and pharmacology of eccrine sweat glands concludes the book. This book is written primarily for dermatologists, whether seasoned veterans or neophytes, and will also be useful to all biologists who are interested in biomedical disciplines.

Table of Contents

  • Preface


    Chapter 1. An Introduction to Skin



    Chapter 2. The Epidermis

    I. Structural Features

    II. Histochemical and Microchemical Properties

    III. Development

    IV. Life Cycle of Epidermal Cells (Keratinocytes)

    V. Properties and Function of Stratum Corneum


    Chapter 3. Other Cells in the Epidermis

    I. Melanocytes

    I. The Cells of Langerhans

    III. Merkel Cells

    Chapter 4. The Dermis

    I. General Considerations

    II. Dermal Components

    III. Cellular Components

    IV. Age Changes in the Dermis

    V. Biological Functions


    Chapter 5. Blood Supply

    I. Introduction

    II. The Vascular Patterns

    III. Arteriovenous Anastomoses (AVA) or Shunts

    IV. Cutaneous Blood Flow and Its Significance

    V. Changes in Skin Circulation

    VI. The Lymphatic System


    Chapter 6. Cutaneous Innervation

    I. Effector Cutaneous Nerves

    II. The Sensory or Afferent Nerves

    III. The Dermal Nerve Network

    IV. Intra epidermal Neuntes

    V. Mucocutaneous End Organs

    VI. Meissner Corpuscles

    VII. Vater-Pacini Corpuscles

    VIII. Comments


    Chapter 7. The Pilary Apparatus

    I. Introduction

    II. Development

    III. Hair Cycle

    IV. Hair Growth in Man

    V. Vascularity

    VI. Innervation

    VII. Pigmentation

    VIII. Keratinization

    IX. Factors That Influence Growth

    X. Alopecia


    Chapter 8. Effects of Malnutrition on the Morphology of Hair Roots

    I. Introduction

    II. Protein Synthesis in the Follicle

    III. Changes in the Hair Shaft

    IV. Changes in Hair Roots


    Chapter 9. Nails

    I. Introduction

    II. Structure

    III. Development

    IV. Formation of the Nail Plate

    V. Keratinization

    VI. Other Cell Types in the Nail

    VII. Regeneration and Growth


    Chapter 10. Sebaceous Glands

    I. Introduction

    II. Development

    III. The Structure

    IV. Growth and Proliferation

    V. Sebaceous Secretion

    VI. Hormonal Control

    VII. Receptor Proteins for Dihydrotestosterone in Sebaceous Glands

    VIII. Lipids

    IX. Enzyme Systems

    X. Innervation

    XI. Function of Sebum

    XII. The Problem of Acne Vulgaris


    Chapter 11. Apocrine Glands

    I. Introduction

    II. Development

    III. Structure of the Gland

    IV. The Secretory Coil

    V. Myoepithelial Cells

    VI. The Structure of the Duct

    VII. Lipids

    VIII. Iron

    IX. Miscellaneous Histochemical Properties

    X. Secretory Process

    XI Composition of Apocrine Secretion

    XII. Pharmacological Responses of Apocrine Sweat Glands

    XIII. The Phylogeny of Sweat Glands


    Chapter 12. Eccrine Sweat Glands

    I. Introduction

    II. Development

    III. Blood Supply

    IV. Structural Features

    V. Ultrastructure

    VI. The Duct

    VII. Cytochemistry

    VIII. Pharmacology

    IX. Factors That Influence the Responsiviness of the Sweat Gland to Cholinergic Drugs

    X. Repeated Injections of Cholinergic Drugs

    XI. Arterial Occlusion

    XII. Handedness

    XIII. Effects of Cholinergic Drugs in Vitro

    XIV. Secretory Activity Stimulated by Cholinergic Drugs

    XV. Adregenic Stimulation of Sweating

    XVI. Effects of Epinephrine in Vitro

    XVII. Possible Mechanisms of Adrenergic Sweating

    XVIII. Comments


    Author Index

    Subject Index

Product details

  • No. of pages: 448
  • Language: English
  • Copyright: © Academic Press 1974
  • Published: April 28, 1974
  • Imprint: Academic Press
  • eBook ISBN: 9780323138697

About the Author

William Montagna

Affiliations and Expertise

Oregon Regional Primate Research Center, Beaverton, U.S.A.

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